Background: “According to the current knowledge, changes in lipid profile in pregnancy is a major contributor in the pathogenesis of preeclampsia. The present study was designed to compare the changes in lipid profile in normal pregnancy and in patients with history of recurrent pre-eclampsia (PE).”
Objective: Assessment the relationship between lipid profiles changes in women with history of recurrent preeclampsia in comparison to normal pregnancy in early pregnancy.
Patients and Methods: Measurement of lipid profile changes in women with history of recurrent preeclampsia (more than two preeclampsia in previous pregnancies) at 12 to 16 weeks of pregnancy and compared to normal pregnancy as a control group who does not have his

Background: Osteoporosis (OP) is a chronic and a progressive disease characterized by low bone mass and micro-architectural deterioration of bone tissue, resulting in an increased risk of fracture. Osteocalcin is a non-collagenous protein synthesized and secreted by osteoblasts. Its main physiological functions are calcium ion homeostasis, maintain the normal bone mineralization rate, inhibit the abnormal formation of hydroxyapatite crystal, and to be involved in bone remodeling through a negative feedback mechanism.
Objective: This study was planned to evaluate serum level of bone formation marker osteocalcin (OC) in postmenopausal women with and without primary osteoporosis; and study the correlation between serum osteocalcin level

Chitinase-3-like 1 protein (YKL-40) is a glycoprotein primarily produced in the arthritic joint and plays a crucial role in inflammatory processes. The aim of the study is to establish the role of YKL-40 as a biomarker for rheumatoid arthritis (RA) compared to proinflammatory biomarkers and disease activity. The study included 58 patients and 18 control. Diseases activity score (DAS-28) and clinical disease activity index (CDAI) were measured. Serum level of YKL-40, tumor necrosis factor-α (TNF-α), interleukin-1B (IL-1β), erythrocyte sedimentation (ESR), rheumatoid factor (RF), C-reactive protein (CRP), and anti-citrullinated protein antibody (ACPA) were assessed. The results showed that the median serum YKL-40 level which was 5.42 

Background: preeclampsia is characterized by endothelial dysfunction with vasoconstriction due to cell adhesion molecules or mediators released by defective placentation. Soluble platelet selectin, one of the cell adhesion molecules, is elevated in many inflammatory conditions including preeclampsia.
Objective: To investigate if soluble platelet-selectin levels can be used as a marker for adverse outcomes in pregnancy complicated with sever preeclampsia
Patients and methods:This study involved 115 pregnant women in their third trimester of pregnancy; divided into Group A: involves 25 pregnant women with preeclampsia complicated by intrauterine growth restriction.Group B: involves 35 pregnant women with preeclampsia without intraute

Background:

Objectives : This prospective   study aimed to  estimate interleukins 1 and 10  levels in acute  hepatitis (G) in Iraqi patients with leukemiaHepatitis G virus and GB virus C (GBV-C)  RNA viruses that were independently identified in 1995, and were subsequently found to be two isolates of the same virus. Blood transfusion is the main risk factor for HGV transmission Immune-mediated mechanisms are believed to play an important pathogenic role in  hepatitis G virus infection. Interleukin-1 (IL-1) plays an important role in the inflammatory process. implying that IL-1 may play a role in viral clearance and  suggesting that IL-1 has direct antiviral

Rheumatoid arthritis (RA), is an autoimmune, and inflammatory disease that is closely related to the destruction of cartilage and bone. DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. Recent evidence has demonstrated that DC-SIGN is involved in the pathophysiological of chronic inflammation, so DC-SIGN has been linked to several autoimmune and may play an essential indicator in the pathogenesis and progression of RA. Therefore, the purpose of this study is to determine the serum level of DC-SIGN in RA patients, as well as the level of DC

Background: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is caused coronavirus disease
2019 (COVID-19) affecting people worldwide. The angiotensin converting enzyme2 (ACE2) represents a
receptor of SARS-CoV-2 on the infected host cell. Apelin or its receptor agonists suppress the production of
angiotensin-converting enzyme (ACE) and angiotensin II (Ang-II) and is characterized by a protective effect
against SARS-CoV-2.
Objective: The study aims to assess the serum level of Elabela biomarker as an early detector for Acute
Kidney Injury (AKI) in patients with COVID-19.
Cases and Methods: This is a case-control study which included 45 hospitalized adult patients in multiple
centers (pu

Background:Gastrointestinal cancers (GITc) is a worldwide problem. In Iraq , Gastric cancer is the 9th commonest of the top cancers while colorectal cancers it is considered as the 7th commonest ten cancers.IL-10 appears to be more of a pro-tumor than anti-tumor properties in both colorectal and gastric cancers.
Objective:is to estimate the serum level of IL-10 in the Iraqi colorectal and gastric cancer Patientsand its relation to the progress of disease.
Patients and Methods:In ourstudy ,54 serum samples werecollected starting from the 1st of January to mid of March 2011, to investigate the IL-10 serum level by using ELISA kit. 38colorectal and gastric cancer patients (H.Pylori +ve) and 16 of healthy control group.
Results: The

Background: Polycystic ovary syndrome (PCOS) women's most prevalent endocrinology condition is a mixture of environmentally and genetically adduced causing PCOS. The relationship between monosaccharide and PCOS is largely unknown.

Objective: This research was designed to investigate the relationship between blood levels of fructose, insulin resistance, and androgen hormone in women with PCOS, and the effect of obesity on the obtained result, as well as to study the efficacy of serum fructose as a biomarker in the diagnosis of PCOS.

Cases and methods: This case-control research study was conducted at the Gynecology Clinic and Infertility Center, in Baghdad Teaching Hospital

Background: Neural tube defects (NTD) are group of heterogeneous and complex congenital anomalies of the CNS. Commonly included in this group anencephaly, spina bifida and
encephaloceles. Anencephaly is the most severe defect; it is always lethal and results in stillbirth or early neonatal demise, is characterized by absence of the brain and cranium above the base of the skull and orbits
Objective: The objective of this study is to assess the relationship between maternal serum zinc level and anencephaly occurrence in women with second -trimester induced abortion due to anencephalic fetus.
Study design and setting: This study is a case- control study, carried out in Baghdad teaching hospital through