Background: we know that TNF-a which is consider an important inflammatory cytokine mediate the inflammatory reactions which occur in the tissues against the infections agents and other causes of inflammation therefore, here we try to study the role of TNF-a in chronic Rheumatic heart disease and the relationship of TNF-a with extent of histopathological.
Back ground: The study was conducted on fifty patients (27 males and 20 females) with chronic renal failure (CRF) undergoing maintenance hemodialysis (HD), at
artificial Kidney unit, Al- Hakeem Hospital / Najaf, during the perioed from April to June 2008.
Patients & methods: Plasma osmolarity ( Posm), plasma creatinine (P cr ) plasma urea (P urea)>plasma sodium (P Na)and plasma potassium ( P k )were measured for
all patients before and after dialysis.
Results: The paired t -test was used to compare the pre-dialysis values with the post dialysis values and simple linear correlation to study the relation between (P
Na), and ( Posm), p values less than 0.05 considered not significant. The result of&
In this paper, an eco-epidemiological model with media coverage effect is proposed and studied. A prey-predator model with modified Leslie-Gower and functional response is studied. An -type of disease in prey is considered. The existence, uniqueness and boundedness of the solution of the model are discussed. The local and global stability of this system are carried out. The conditions for the persistence of all species are established. The local bifurcation in the model is studied. Finally, numerical simulations are conducted to illustrate the analytical results.
plaque forming assay was used enumerate the number of plaque forming cells of anti-HBc in eight patintes with chronic hepatitis and eight health
Thyroid disease is a common disease affecting millions worldwide. Early diagnosis and treatment of thyroid disease can help prevent more serious complications and improve long-term health outcomes. However, thyroid disease diagnosis can be challenging due to its variable symptoms and limited diagnostic tests. By processing enormous amounts of data and seeing trends that may not be immediately evident to human doctors, Machine Learning (ML) algorithms may be capable of increasing the accuracy with which thyroid disease is diagnosed. This study seeks to discover the most recent ML-based and data-driven developments and strategies for diagnosing thyroid disease while considering the challenges associated with imbalanced data in thyroid dise
... Show MoreBackground: Arterial functional changes reflected by vascular stiffness might occur at early stages of cardiovascular disease before the morphological alterations reflected by increasing the intima media thickness and it is widely used as a very sensitive indicator of functional vascular damage.
Objectives: This study is aimed to correlate ultrasound detected vascular functional changes with the severity and extent of coronary artery disease.
Patients and methods: Sonographic scans were performed on 100 Patients (61males, 39 females) with an age range of (40-65years) for measuring carotid and brachial arteries end diastolic and end systolic diameters to calculate vascular stiffness index . Coronary CT angio
Background: Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease that is characterized by severe synovial inflammation, cartilage erosion, bone loss, and generalized vasculopathy. Although the immunologic mechanism of RA is still unclear, it is now thought to be a primarily Th17-driven disease. Along with other factors, IL-23 stimulates the expansion of Th17 cells from naive CD4+ T cells.
Objective: The objective of this study is to assess the circulating levels of interleukin (IL)-23 in rheumatoid arthritis (RA) and determine the correlation between plasma/serum IL-23 levels and disease activity. So, we performed a systematic review with meta-analysis comparing
... Show MoreThe present study aimed to investigate the histological changes of heart, lung, liver and kidney which caused by different concentrations (10, 20 and 40 mg/kg) of Ivabradine. Results of the study revealed some histological changes represented by aggregation of the lymphocytes around respiratory bronchioles of the lung. In the liver, the drug caused hepatocyte necrosis and infiltration of the lymphocytes. In Kidney, there are no histopathological modifications in the tissue after the animals treated with 10 mg\kg of Ivabradine. When the animals treated with Ivabradine drug at 20mg/kg of bw, dose showed vascular congestion between myocardial fibers of heart. Emphysematous c
... Show MoreBackground: Coronary artery spasm occurs spontaneously leading to the syndrome of variant angina. It occurs in about 15 % of patients undergoing coronary angiography.
Objectives: This study sought to estimate the rate of coronary artery spasm that occurs during coronary angiography and percutaneous coronary intervention with their risk factors in patients admitted to the Iraqi center for heart disease.
Methods: This is a cross sectional observational study, We prospectively collected the data of patients over six months period (from August 2014 till February 2015 ) who developed coronary artery spasm during cardiac catheterization (diagnostic and therapeutic).
Results: Out of 1274 patients, 106 patients developed coronary artery
Back ground: Celiac disease (CD) is an immune–mediated enteropathy induced by gluten with broad spectrum of presentation, many patients with atypical symptoms or clinically silent remain undiagnosed, and are at risk of long-term complications.
Objective: The aim of the present study is to determine the of prevalence celiac disease in children with short stature.
Patient and Methods: In this prospective study, 307 children 181(58.9%)males and 126(41.1%) females ,with ages ranging from 3 to 17.5years ( mean 12.2 ±3.4) with short statures (height below 3rd percentile adjusted for age and sex) attending the consultation room of endocrinology/ Welfare Teaching Hospital/medical city- Baghdad , were enrolled in this study from the firs
Background: several factors render chronic lymphocytic leukemia an interesting subject for study by researchers. These include marked progress in understanding the molecular biology of normal and neoplastic lymphoid cells and recent advances in molecular genetics techniques. Among molecular markers, p-53 cancer suppressor gene has been widely studied.
Objectives: is to correlate p-53 protein expression in chronic lymphocytic leukemia, as examined by immunohistochemical method, with some pathological and clinical parameters.
Patients and methods: this is a retrospective study; whereby archival paraffin-embedded bone marrow tissue blocks along with the clinical and hematological records of fifty patients (35 males and 15 females), wi