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Captopril versus enalapril in the protection of the gastric mucosa against NSAID induced gastric mucosal injury in rats
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Background: Different mechanisms have been suggested for the development of nonsteroidal antiinflammatory drugs (NSAIDs) induced gastropathy. Angiotensin converting enzyme inhibitors have been suggested to have gastroprotective effects. This study investigates the gastroprotective effects of Angiotensin converting enzyme inhibitors, captopril and enalapril on indomethacin induced gastric mucosal damage in rats .
Materials and methods: The study was conducted on 50 adult male albino rats, divided into 5 groups, the first served as a control received the vehicle , the second received indomethacin orally of 60mg/kg. The third and fourth groups were pretreated orally 30 minute prior indomethacin with either captopril or enalapril. In order to study the possible role of nitric oxide (NO) in the gastroprotective effect of captopril; intraperitoneal NG-L-Arginine Methyl Ester (L-NAME) a nitric oxide synthase inhibitor was given 30 minutes prior to captopril administration followed by indomethacin and this served as fifth group. The rats were then sacrificed after 4 hours and their stomachs were isolated and submitted to macroscopical assessment and for the measurement of the gastric prostaglandinE2 (PGE2), and myeloperoxidase (MPO).
Results: Captopril in a dose of 15 mg/kg produced a significant reduction (p <0.05) in the gastric damage score .These protective effects were associated with a significant increase (p <0.05) in gastric PGE2 levels and marked decrease (p <0.05) in MPO activity, L-NAME pretreatment didn't abrogate the effects of captopril. Enalapril pretreatment failed to show the gastroprotective effects of captopril.
Conclusions: The prophylactic use of captopril in this study prevented indomethacin induced gastropathy .This protective effect was associated with PGE2 upregulation and decreased oxyradical generation reflected by a decrease in MPO activity .Enalapril failed to produce the gastroprotective effects of captopril. 

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Publication Date
Mon Jan 29 2018
Journal Name
Iraqi Journal Of Science
The Antibacterial activity of crud Bacteriocin- like substance against food borne bacterial pathogens: no
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Lactobacillus is one of Lactic Acid Bacteria group, they are known to exhibit antagonistic activity against pathogenic organisms. This study evaluates the protective effect of Lactobacillus acidophilus Crud Bacteriocin like substance against growth of some food borne pathogenic bacteria. Antimicrobial effect of crud bacteriocin like substance was tested against the growth of S. typhi and S. aureus that isolated from food samples by agar well diffusion assay.
The results showed that the crud extract of bacteriocin like substance had antibacterial activity against the two tested bacteria, and the effect against S. typhi was greater than that of S. aureus , the zone of inhibition was (15)mm against S.&n

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Publication Date
Wed Jan 01 2020
Journal Name
Research Journal Of Pharmacy And Technology
The Genoprotective Activity of Aqueous Green Tea extract against Metronidazole and Tinidazole Genotoxic Effect
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Aim: The study designed to evaluate the Geno-protective effect of green tea extract against genotoxicity induced by metronidazole and tinidazole. Methods: Thirty-six mice were used, For each experiment, The animals divided into 6 groups: Group I- Negative control administered distilled water; Group II-Healthy mice treated with metronidazole alone, Group III- Healthy mice treated with tinidazole alone; Group IV- Healthy mice administered green tea extract alone Group V- Healthy mice treated with metronidazole, followed by green tea extract administration, Group VI- Healthy mice treated with tinidazole, followed by administration of green tea extract. Results: treatment with Tinidazole significantly increase total chromosomal aberration (0.18

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Scopus
Publication Date
Mon Jul 01 2019
Journal Name
Iop Conference Series: Materials Science And Engineering
Corrosion protection of pure titanium implant by electrochemical deposition of hydroxyapatite post-anodizing
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In this study, a Hydroxyapatite (HA) coating was prepared on a titanium implant by an electrochemical deposition process. The titanium pre-treatment by anodizing in 1.65 mol/L sulfuric acid with (10V) at room temperature. The deposition was all conducted at a constant voltage of 6.0 V, for 1 h at room temperature. The coatings thus prepared were characterized with Fourier transform infrared spectroscopy (FTIR) and thickness of the coated layer.The electrochemical deposition of HA occurred on the titanium as a cathode. Coated titanium by HA after anodizing revealed a good corrosion protection efficiency even at a temperature ranged (293-323) K in artificial saliva. Activation energy and pre-exponential factor (kinetic parameters) were calcul

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Scopus (12)
Scopus
Publication Date
Tue May 16 2023
Journal Name
Journal Of Engineering
Application of Wavelet Packet and S Transforms for Differential Protection of Power Transformer
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The differential protection of power transformers appears to be more difficult than any type of protection for any other part or element in a power system. Such difficulties arise from the existence of the magnetizing inrush phenomenon. Therefore, it is necessary to recognize between inrush current and the current arise from internal faults. In this paper, two approaches based on wavelet packet transform (WPT) and S-transform (ST) are applied to recognize different types of currents following in the transformer. In WPT approach, the selection of optimal mother wavelet and the optimal number of resolution is carried out using minimum description length (MDL) criteria before taking the decision for the extraction features from the WPT tree

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Publication Date
Sat Dec 30 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
The Insecticidal Effects of Nogos and Sumicidin Against Eggs and Larvae of The Mosquito Culex pipiens L.(Diptera: Culicidae)
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The  two  i nsecticides  Nogos and  Sumicidin  were  tested  for  their activity  against larvae  and  eggs  of  Culex  pipiens under  laboratory conditi on.

Third  instar  larvae  were  exposed  for  24, 48 and  72.  hrs  to five concentrations  each insecticide  test: 0.0005, 0.005, 0.05, 0.5 and  1.0 ppm. The same concentrations were used to test the eggs hatching.

The  results showed   that Nogos  was more effective  than  Sumicidin. This insecticide (Nogos)  demonstrated  larval  mortal ities (94%) after

24  brs and (9

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Publication Date
Thu Jun 30 2016
Journal Name
Al-kindy College Medical Journal
Adenoidectomy with Myringotomy and Tympanostomy Tube Versus Adenoidectomy with Myringotomy in Treatment of Otitis Media with Effusion in 5-7 Years Old Children
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Background: Adenoiditis is a common cause of otitis media with effusion (OME) in children & perhaps OME is one of the most common diseases leads to hearing impairment in children with subsequent impairment of speech development & learning difficulties , however, treatment remains controversial. Objectives: To evaluate if there is a significant advantage of tympanostomy tube insertion in association with adenoidectomy over adenoidectomy in association with myringotomy alone in treatment of children with OMEType of the study: This is a prospective study. Patients & methods: The study consisted from 63 children diagnosed as cases of bilateral OME & variable degrees of adenoid hypertrophy. The patients were divided randomly i

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Publication Date
Thu Jan 02 2014
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Single-layer seromuscular Continuous Versus Two-Layers Intestinal Anastomosis Of Small bowel in Baghdad Teaching Hospital (A prospective Study)
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Background: Anastomosis may be done with the help of stapling devices, by using double layered suturing technique or by a single layer technique.
Patients and methods:
A prospective study conducted in Baghdad Teaching Hospital, Iraq.  A total of sixty- four patients were included in this study. They were divided into two groups; group A, 28 patients, single layer seromuscular continuous anastomosis was done and group B, 36 patients underwent conventional double layered anastomosis.Objective: The aim of the study is to prove that a single layer continuous technique can be constructed in a significantly less time with similar rate of complications compared with two layers technique

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Publication Date
Wed Jan 19 2022
Journal Name
Iraqi Journal Of Science
In Vitro Assessment of Miltefosine Activity Against Promastigotes and Axenic Amastigotes of Leishmania tropica
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Leishmaniasis is a worldwide disease still treated with expensive compounds that present severe side effects, and are frequently ineffective emphasizing the importance to search effective compounds against this disease. Miltefosine drug (HePC) that used as antitumor agent has been used against Leishmania tropica in two forms promastigote and axenic amastigote in vitro conditions. Different concentrations (5, 10, 15, 20, 25 and 30 μM) of HePC were performed and exposed to both parasite forms in comparison to sodium stibogluconate (Sb) drug. Parasites viability then was determined using MTT assay after 12, 24, and 48hr of exposure. DNA was extracted from treated and untreated parasites after 48hr of exposure and qualitative analysis of th

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Publication Date
Mon Oct 30 2023
Journal Name
Iraqi Journal Of Science
Investigation The Effect of Pfizer , AstraZeneca , and Sinopharm Vaccines Against SARS-CoV-2 in Iraq Using Cluster of Differentiation 4 (CD4 ) and Vitamin D3
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     The research aimed to study the vaccination efficiency against the emerging virus SARS-CoV-2, which includes Pfizer, AstraZeneca and Sinopharm vaccines that  are  used exclusively in Iraq, by measuring the level of immune cells CD4+ as well as vitamin D3 using ELISA technology. Taking  serums  were taken from vaccinated individuals: 20 uninfected before individuals who got a vaccination and 20 people with prior infections who had the vaccine (for each type of the three vaccines). Samples were collected 21 days following the second dose as well as 3 to 6 months thereafter. The results showed that the most effective vaccine was AstraZeneca  and  the results of T-cells were the highest compared to Pfizer and Sinop

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Publication Date
Sun Sep 05 2010
Journal Name
Baghdad Science Journal
The Composition operator on hardy space H2 Induced by ?(z)=sz+t where , and
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We study in this paper the composition operator of induced by the function ?(z)=sz+t where , and We characterize the normal composition operator C? on Hardy space H2 and other related classes of operators. In addition to that we study the essential normality of C? and give some other partial results which are new to the best of our knowledge.

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