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Descriptive study of incidence of side effects of Pegylated interferon alpha therapy and their relation to age, gender, duration of treatment and type of hepatitis in 50 Iraqi patients.
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Background: Hepatitis C and B is common disease all over the world and their chronicity is a social and medical problem so medical treatment by alpha interferon can change the mortality and morbidity.
Object: Identify the incidence of the side effects of pegylated interferon alpha in a sample of Iraqi patients with chronic hepatitis B&C and their relation to age, gender, duration of treatment and type of hepatitis comparing them with the literatures from other countries.
Patients and methods:A descriptive case series study was conducted on 50 patients, 24 male and 26 female, with established diagnosis of hepatitis B(20 patients)and C(30 patients) who attend Baghdad Teaching hospital and Gastroenterology and Hepatology centre in Baghdad between the period of January 2009 and October 2010 with follow up over at least 3 months.
A direct interview with detailed history and thorough clinical examination with some simple laboratory investigation were done to determine any of the documented side effects of alpha interferon therapy or discover new side effects not elicited in the studies done on other populations.
Results: Flu-like illness is the most common side effect (84%), followed by fatigue, anorexia, local reaction and neuropsychiatric side effects while Neutropenia, lymphopenia and thyroiditis are rare.
There is no significant difference in the incidence of side effects between age groups with the exception of constipation which occurs more in younger age group. Arthralgia, palpitation, eczema, itching and rash increase in incidence with prolonged duration of treatment.
There is no significant difference in incidence of side effects between both genders apart from hypertension (more in female) and dizziness (more in male).
There is no significant difference in incidence of side effects between patients with hepatitis B&C but anemia occurs more in patients with hepatitis C and tremor reported more in patients with hepatitis B.
Conclusion: Almost all patients on treatment with interferon-based regimen will experience adverse events that can threaten good adherence. Flu-like illness is the most common side effect (84%), followed by fatigue, anorexia, local reaction and neuropsychiatric side effects (depression, nervousness, insomnia).
The higher incidence of anemia in patients with hepatitis C is mostly due to concomitant ribavirin therapy.
Age, gender, type of hepatitis and duration of treatment can affect the incidence of interferon therapy.

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Publication Date
Sun May 02 2021
Journal Name
Journal Of Accounting And Financial Studies ( Jafs )
Evaluating the level of performance according to the tax diagnosis TADAT: applied research in the General Tax Authority
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The aim of the research is to indicate the degree of arrangement of the tax branches discussed and the level of efficiency of their performance according to the dimensions approved in the tax diagnostic tool (TADAT). The checklist has been approved as a main tool in collecting data and information from the tax branches of the General Authority for Taxes and the number (8) branches represented by (Karrada , Karakh Center, Al-Rusafa, New Baghdad, Al-Dora, Karakh Al-Tafim, Al-Kadhimiya, Al-Bayaa),  The statistical program (spss) was used to calculate the weighted arithmetic media, and we reached the research to a number of conclusions, the most important of which were: - Each of the subsections (Karkh Al-Ahram and Karrada) achieved an

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Publication Date
Wed Oct 01 2014
Journal Name
Journal Of Economics And Administrative Sciences
The role of paid the offices of the Inspectors General on mutation fraud Crimes
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       Fraud crimes, which is a form of crimes against the funds in public office, is one of the crimes of traditional and cutting-edge in the same time, but it took a distinct character from other traditional crimes because of what is based upon, behavioral fundamentals and foundations and expressive image of personal qualities, concentrated in the mental work, the inventive sophistication, and skillful abilities of the perpetrators of these crimes, in addition to what is owned by crooks today a behavioral ability represented in underestimating laws and instructions. Fraud is considered one of the organized crime methods It is the most important method of its methods, all crimes practiced by the cro

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Publication Date
Sat Jan 11 2025
Journal Name
Journal Mustansiriyah Of Sports Science
بناء وتقنين مقياس انماط الثقافة التنظيمية ألعضاء االتحاد العراقي المركزي بالكرة الطائرة من وجهة نظر المعنيين باللعبة
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تعد الثقافة التنظيمية في المجال االداري وكذلك الرياضي من المفاهيم الحديثة لذا وجب التعرف عليها من عدة اتجاهات لمعرفة تكوينها واب عادها والنظريات التي تناولتها لتكوين رؤية تختلف عن االخرين لما لها من دور مهم ونافع في مختلف المؤسسات ومنها االتحادات الرياضية، ولعل لعلوم الرياضة واالختبار والقياس على وجه الخصوص الدور الرئيس في المساعدة بإيجاد وسيلة علمية وتطبيقها على االعضاء لمعرفة انماط الثقافة لديهم ومن

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Publication Date
Thu Aug 30 2018
Journal Name
Iraqi Journal Of Science
Calculation of Pollution Indicators and Health Hazards of Heavy Elements in Surface Soils in Samarra City
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The current study focuses on the assessment of pollution indicators and health risks of heavy elements in the surface soil of Samarra City. Twelve soil sample collected from different sites in Samarra City, analysis of soil sample to find the heavy metals concentrations  which As, Br, Co, Cr, Cu, Mn, Mo, Ni, Pb, Sn, V, Zn, Zr, U, B, Cd, Hg, Th, Ce, La, Th, B, Ba .The results are compared with limit of world standard (12). The higher values which refer to pollution in heavy metal are  Cr, Cu, Ni, Zn, Zr, Cd due to industry activity and Hg higher concentration because of Pharmaceutical Industries and Medical Waste . The high concentration in V, Br, Mo, Se, As  because of agriculture activity. The enrichment factor calculated

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Publication Date
Sat Feb 18 2023
Journal Name
Iraqi Journal Of Pharmaceutical Sciences
Preparation and In-Vitro Evaluation of Floating Oral In- Situ Gel of Montelukast Sodium (Conference Paper) #
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Publication Date
Thu Jan 13 2022
Journal Name
Iraqi Journal Of Science
Detection of Cadmium and Chromium in some Facial Cosmetics
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This study was done to compare among 120 new and used cosmetic brands to determine the heavy metals concentrations (Cadmium, Chromium) in (face foundation, powder and blushers). Sixty new cosmetic products were bought from local markets in Baghdad city (twenty different brands foe each cosmetic products), while sixty used cosmetic products were collected from Iraqi women and they had been stored for a long time. This study proved that not all analyzed cosmetic products containing heavy metals concentrations and all concentrations are under Iraqi acceptable limits except one new blusher product which contained chromium with (28 ppm), but all used cosmetic products have shown better results in concentrations of heavy metals than new produc

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Publication Date
Tue Feb 13 2018
Journal Name
Revista Publicando
Cognitive bases of phono-grammar in russian and arabic
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Publication Date
Fri Nov 11 2022
Journal Name
Al-nisour Journal For Medical Sciences
Spectrophotometric determination of sulfamethoxazole in pure and pharmaceutical formulations
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New, easy, simple, and fast spectral method for estimation of sulfamethoxazole (SMZ) in pure and pharmaceutical forms. The proposed method is based on the azotization of the drug compound by sodium nitrite in an acidic medium and then coupling with 2,3dimethyl phenol reagent (DMP) in a basic medium to yield an orange-coloured dye which shows λmax at 402 nm. Different affection of the optimization reaction has been completed, following the classical univariate sequence. The concentration of sulfamethoxazole about (1-15) μg. mL-1 with molar absorptivity of (14943.461) L.mol1 .cm-1 that obeyed Beer’s law. The detection and quantification limits were (0.852, 2.583) μg. mL-1 respectively, while the value of Sandell’s sensitivity (

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Publication Date
Sat Jan 11 2025
Journal Name
Journal Of Baghdad College Of Dentistry
Salivary level of RANKL and OPG in chronic periodontitis
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Background: Periodontal diseases are initiated by microbial plaque, which accumulates in the sulcular region and induces an inflammatory response. The Receptor activator of nuclear factor-kappa B ligand / osteoprotegerin (RANKL/OPG) axis is involved in the regulation of bone metabolism in periodontitis, in which an increase in receptor activator of nuclear factor-kappa B ligand or a decrease in osteoprotegerin can tip the balance in favor of osteoclastogenesis and the resorption of alveolar bone that is the hallmark of periodontitis. This study was performed to investigate the role of salivary levels of RANKL and OPG in pathogenesis of chronic periodontitis. Subjects and Methods: Fifty five subjects with chronic periodontitis with ages rang

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Publication Date
Tue Jun 15 2021
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Nanosuspensions of Selexipag: Formulation, Characterization, and in vitro Evaluation
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Selexipag is an orally selective long-acting prostacyclin receptor agonist, which indicated for the treatment of pulmonary arterial hypertension. It is practically insoluble in water ( class II, according to BCS). This work aims to prepare and optimized Selexipag nanosuspensions to achieve an enhancement in the in vitro dissolution rate. The solvent antisolvent precipitation method was used for the production of nanosuspension, and the effect of formulation parameters (stabilizer type, drug: stabilizer ratio, and use of co-stabilizer) and process parameter (stirring speed) on the particle size and polydispersity index were studied. SLPNS prepared with Soluplus® as amain stabilizer (F15) showed the smallest particle size 47nm wi

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