Preferred Language
Articles
/
iqjmc-778
Glycated haemoglobin as a dual biomarker Association between HbA1c and dyslipidemia in type 2 diabetic patients
...Show More Authors

Background: Diabetic patients with accompanied dyslipidemia are soft targets for cardiovascular diseases. An early intervention to normalize circulating lipids has been shown to reduce
cardiovascular complications and mortality. Glycated hemoglobin (HbA1c) is a routinely used marker for long-term glycemic control.
Objective: to investigate the role of HbA1c as a marker of circulating lipids in type 2 diabetic patients
Subjects and Methods: A total of 450 type 2 diabetic patients (214 males and 236 females), mean age was 55.5 ± 9.35. who attended the National Diabetic Center, Al-Mustansiria university during the period from December 2010 to May 2011 were included in this study Fasting venous blood samples were collected from all the subjects. .HbA1c was estimated by high performance liquid chromatography The Serum was used for analyzing Fasting Blood Glucose (FBG), Total cholesterol (TC),HDL-cholesterol(HDL-C), Triglycerides(TG). Dyslipidemia was defined as per the National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III guidelines. Diabetes was defined as per American diabetes association criteria. The statistical analysis was done by SPSS statistical package version 17.
Results: Statistically significant positive correlation was observed between HbA1C and Total Cholesterol (P=0.000), LDL-C (P=0.000), LDL-C/HDL-C ratio (P=0.001), Non-HDL-C (P=0.000)
and Risk ratio (P=0.000). The correlation of HbA1c with triglycerides (TG) was positive and statistically significant (P=0.033). Patients with HbA1c value > 7.0 had significantly higher value of
TC, TG, LDL-C, LDL-C/HDL-C ratio, non-HDL-C and risk ratio ( TC/HDL-C) as compared to the patients with HbA1c ≤ 7.0%. However, there was no significant difference in value of HDL-C
between the two groups.
Conclusion: HbA1c can be used as a potential biomarker for predicting dyslipidemia in type 2 diabetic patients in addition to glycemic control hence early diagnosis can be accomplished through relatively inexpensive blood testing.

Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Tue Oct 05 2021
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Association between HbA1c and dyslipidemia among sample of Iraqi Patients with Type2 DM
...Show More Authors

Background: Diabetic Mellitus is considered as a public health concern. More than 8 percent of the United States has diabetes. Diabetes is a serious risk factor for Atherosclerotic cardiovascular disease (ASCVD) and an important cause of mortality. ASCVD is the commonest cause of death in the Western world. Diabetes was defined as a high risk condition for ASCVD. In adults with diabetes with ASCVD or multiple ASCVD risk factors it is important to prescribe high intensity statin to reduce LDL at least to 50%.

Objective: To investigate association between dyslipidemia and HbA1c and to detect benefit of using some statins in decreases the risk of CVD.

Material and method: A

... Show More
View Publication Preview PDF
Crossref (4)
Crossref
Publication Date
Wed Dec 30 2015
Journal Name
Al-kindy College Medical Journal
Association between glycaemic control and serum lipid profile in type 2 diabetic patients: Glycatedhaemoglobin as a dual biomarker
...Show More Authors

Background: Patients with type 2 diabetes have an increased prevalence of lipid abnormalities, contributing to their high risk of cardiovascular diseases (CVD).Glycated hemoglobin (HbA1c) is a routinely used marker for long-term glycemic control. In accordance with its function as an indicator for the mean blood glucose level, HbA1c predicts the risk for the development of diabetic complications in diabetic patients[2].Apart from classical risk factors like dyslipidemia, HbA1c has now been regarded as an independent risk factor for (CVD) in subjects with or without diabetes.Objective The aim of this study was to find out association between glycaemic control (HbA1c as a marker) and serum lipid profile in type 2 diabetic patients.Methods

... Show More
View Publication Preview PDF
Publication Date
Mon Jan 16 2023
Journal Name
Iraqi National Journal Of Nursing Specialties
Type 2 Diabetic Patients’ Knowledge Regarding Preventive Measures of Diabetic Foot
...Show More Authors

Objective: Assess type 2 diabetic patients’ knowledge regarding preventive measures of diabetic foot. Find out the relationship between of type 2 diabetic patients’ knowledge regarding preventive measures of diabetic foot with certain sociodemographic characteristics

Methodology: A descriptive study was carried out from (2nd January 2022 to 26th March 2022).  A non –probability (purposive) sample of (60) adult patients who are diagnosed with type2 diabetes mellitus these patients have met the study criteria which was selected from Imam AL-Hussein Medical-City. The study instrument consist of two section: (Demographic Information Sheet, and Foot Care Outcome Expectation

... Show More
View Publication Preview PDF
Publication Date
Sun Apr 02 2017
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Neutrophil gelatinase associated lipocalin (NGAL) in early detection of nephropathy in type 2 diabetic Iraqi patients
...Show More Authors

Background: Diabetic nephropathy is a common complication of diabetes mellitus type2. The neutrophil gelatinase Associated lippocallin (NGAL) is an ubiquitous protein consist of 178 amino acid. NGAL can be identified in plasma and urine starting 2- 4 hours after a kidney injury resulting changes in glomerular filtration and tubular reabsorption and with increased secretion in tubular epithelial cells.
Objective: This study aimed to evaluate the role of serum Neutrophil Gelatinse Associated Lipocallin (NGAL) in early detection nephropathy.
Method : This study was conducted in Medical City, Baghdad Teaching Hospital during the period from December 2015to June 2016.The study included (90) subjects with age range between (30 – 56)yea

... Show More
View Publication Preview PDF
Crossref
Publication Date
Mon Apr 01 2013
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Serum level of adiponectin and leptin in type 2 diabetic Cigarette smokers.
...Show More Authors

Background: Cigarette smoking is the leading avoidable cause of morbidity and mortality in the general population; however its effects on people with diabetes are even more profound. The adipocytokines  leptin and  adiponectin  play an important role in regulating glycemia, lipidemia, endothelial dysfunction, and proinflammatory mechanisms .

Objective: We aimed to investigate the profile of  adiponectin and leptin in type 2 diabetic smokers and non- smokers.

Patient and Methods: Ninety overweight males attending the Teaching Laboratories, Medical City were enrolled in this study, they were arranged as 30 diabetics non smoker, 30 diabetics smokers and 3

... Show More
View Publication Preview PDF
Crossref (1)
Crossref
Publication Date
Sun Oct 01 2023
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Atherogenic Indices in Type 2 Diabetic Iraqi Patients and Its Association with Cardiovascular Disease Risk
...Show More Authors

Background: Diabetes is a serious risk factor for atherosclerotic cardiovascular disease and an important cause of mortality. Dyslipidemia is commonly related to type 2 diabetes, and the atherogenic index of plasma is a strong marker to predict the risk of atherosclerosis and coronary heart disease.

Objective: To study the association of atherogenic indices lipids in type 2 diabetic Iraqi patients with cardiovascular disease.

Patients and Methods: This clinical study was conducted at Baghdad Teaching Hospital/ Medical City-Baghdad from October 2022 to February 2023. Sixty type 2 diabetic patients were recruited for this study: 30 patients with cardiovascular disease and 30

... Show More
View Publication Preview PDF
Crossref
Publication Date
Fri Jan 13 2023
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Effects of liraglutide on weight control and blood pressure in type 2 diabetes mellitus Iraqi patients
...Show More Authors

Abstract

 Background: Diabetes mellitus is the most common endocrine illness, affecting an increasing number of people all over the world. It is caused by a lack, or inadequate synthesis of insulin by the pancreas leading to an increase in blood glucose concentrations. Type 2 diabetes mellitus is the most strongly linked disease to obesity of all disorders. The number of obesity-related diabetes is predicted to reach 300 million by 2025. The term 'diabesity' was coined as a result of this strong link, therefore, weight loss is seen as a key therapeutic goal in the prevention and management of type 2 diabetes mellitus. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agon

... Show More
View Publication
Publication Date
Fri Apr 01 2022
Journal Name
Baghdad Science Journal
The Cut-off Values of Triglycerides - Glucose Index for Metabolic Syndrome Associated with Type 2 Diabetes Mellitus
...Show More Authors

       The co-occurrence of metabolic syndrome with type 2 diabetes mellitus (T2DM) will potentiate the morbidity and mortality that may be associated with each case. Fasting triglycerides-glucose index (TyG index) has been recommended as a useful marker to predict metabolic syndrome. Our study aimed to introduce gender-specific cut-off values of triglycerides- glucose index   for diagnosing metabolic syndrome associated with type 2 diabetes mellitus. The data were collected from Baghdad hospitals between May - December 2019. The number of eligible participants was 424. National cholesterol education program, Adult Treatment Panel III criteria were used to define metabolic syndrome. Measurement of fasting blood glucose, lipid pro

... Show More
View Publication Preview PDF
Scopus (5)
Crossref (1)
Scopus Clarivate Crossref
Publication Date
Mon Jul 01 2013
Journal Name
Journal Of The Faculty Of Medicine Baghdad
The Relationship between Family History and C-peptide Level in Type2 Diabetic Patients
...Show More Authors

Background: Family history of type 2 diabetes is a major risk factor for type 2 diabetes. Type 2 diabetes is characterized by progressive β-cell dysfunction; many investigators have used C peptide levels as a biomarker of β-cell function.

Objective: the current study was design to investigate the impact of family history on biochemical characteristics (c-peptide, HbA1c, lipid profile, insulin secretion, insulin sensitivity and insulin resistance.

J Fac Med Baghdad

2013; Vol.55, No .3

Received Feb .2013

Accepted July.2013

Subjects and me

... Show More
View Publication Preview PDF
Crossref
Publication Date
Mon Jul 01 2013
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Homestasis Model Assessment–Adiponectin ratio and Adiponectin –Resistin index as markers of insulin resistance in type 2diabetes mellitus
...Show More Authors

Background: Insulin resistance (IR) is an important clinical and biochemical determinant of diabetes and many other clinical states. The gold standard method for IR estimation is the hyperinsulinemic euglycaemic glucose clamp. Adiponectin and resistin are adipocytes derived hormones that play important role in the regulation of glucose, fat metabolism and insulin resistance.
Objective: this study aimed to assess the validity of Homestasis Model Assessment–Adiponectin ratio and Adiponectin –Resistin index as markers of insulin resistance in type 2 diabetic mellitus (T2DM) patients.
Design: Ninety (T2DM) overweight male subjects were enrolled in this cross sectional study, detailed history, physical examination and anthropometric

... Show More
View Publication Preview PDF
Crossref (1)
Crossref