Preferred Language
Articles
/
iqjmc-772
Detection of Human papillomavirus in surface epithelial ovarian carcinoma using in situ hybridization technique
...Show More Authors

Background: The role of Human papillomaviruses (HPV) in the etiology of ovarian cancer remains unclear and the results are controversial. Several studies have verified the presence of HPV DNA in both malignant and benign ovarian tumors.
Objectives: Determine the percentage of detection of HPV high (16&18) and low risk types (6&11) in surface epithelial ovarian carcinoma compared to benign and control groups.
Materials And Methods: Molecular detection and genotyping of HPV DNA were performed in 76 ovarian tissue blocks by using in situ hybridization (ISH) technique for detecting and localization of high risk HPV (16 and 18) and low risk HPV (6&11) types.
Results: The presence of ISH signals for HPV DNA in benign group (71%) was higher than that found in malignant group (64%). HPV 16 was the most predominant type followed by HPV18, 6, and 11 respectively in both malignant and benign groups. High risk HPV were presented with low score and high intensity in both malignant and benign tumors. Low risk HPV types were detected in high score and intensity in benign tumors which significantly differed from that with malignant tumors, which revealed low score and low intensity. The percentage of co-infection of low risk HPV6&11 in benign group was higher (16.9%) than malignant group (7.1%). Only significant difference was found in combination of both high and low risk HPV types.
Conclusions: This finding reflects a possible role of HPV virus in the carcinogenesis of ovarian tumors. HPV infection may play a relative role in the pathogenesis of ovarian carcinomas or it could facilitate its progression.

Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Sun Jan 01 2023
Journal Name
Journal Of Advanced Pharmaceutical Technology & Research
Use of factorial design in formulation and evaluation of intrarectal in situ gel of sumatriptan
...Show More Authors

View Publication
Scopus (3)
Crossref (3)
Scopus Clarivate Crossref
Publication Date
Sun Apr 01 2012
Journal Name
Journal Of The Faculty Of Medicine Baghdad
The effect of inhibin B on ovarian response in subjects with polycystic ovary
...Show More Authors

Background: Inhibin B hormone is one of the indicative parameters in measuring ovarian reserve ,which is important to be evaluated, since it is one of the markers of the female reproductive potential especially in polycystic ovary patients (PCOS) which is a common cause of anovulatory infertility.
Patients and methods: Ninty four infertile polycystic ovaries women, attending the infertility clinic at Baghdad teaching hospital, during the period of October 2005 to December 2006, were compared to 62 control group women who have unexplained infertility. After exact history and examination, inhibin level measurement was done in cycle day 3, the patients are divided according to age into 2 groups (more than 35

... Show More
View Publication Preview PDF
Crossref
Publication Date
Sun Dec 22 2019
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Formulation and Evaluation of Sustained Release Sumatriptan Mucoadhesive Intranasal in-Situ Gel
...Show More Authors

    

Sumatriptan(ST) is a selective agonist at serotonin 5-HTI receptors, as well as 5-HT1B/1D subtypes. It is effective for acute migraine attacks, but has a short half  life (about 2 hours) and low oral bioavailability (15%). The purpose of this study was to develop and optimize nasal mucoadhesive in-situ gel(IG) of ST to enhance nasal residence time for migraine management. Cold method was used to prepare different formulas of  ST nasal IG, using thermosensitive polymers (poloxamer 407  alone or with poloxamer 188) with a mucoadhesive polymer hyaluronic acid (HA) which were examined for gelation temperature and gelation time, pH, drug content, gel strength, spreadability, muc

... Show More
View Publication Preview PDF
Scopus (13)
Crossref (3)
Scopus Crossref
Publication Date
Sun Jun 07 2015
Journal Name
Baghdad Science Journal
Serum Vascular Endothelial Growth Factor VEGF and Interlukin-8 As a Novel Biomarkers For Early Detection of Ovarian Tumors
...Show More Authors

Epithelial ovarian cancer is the leading cause of cancer deaths from gynecological malignancies. Angiogenesis is considered essential for tumor growth and the development of metastases. VEGF and IL?8 are potent angiostimulatory molecules and their expression has been demonstrated in many solid tumors, including ovarian cancer.VEGF and IL-8 concentrations were measured by ELISA test (HumanVEGF,IL-8). Bioassay ELISA/ US Biological / USA).The median VEGF and IL-8 levels were significantly higher in the sera of ovarian cancer patients than in those with benign tumors and in healthy controls.Pretreatment VEGF and IL-8 serum levels might be regarded as an additional tool in the differentiation of ovarian tumors.

View Publication Preview PDF
Crossref
Publication Date
Mon Dec 01 2014
Journal Name
Iraqi Journal Of Science,
Detection of human leukocyte antigen and celiac disease auto antibodies in serum of patients with multiple sclerosis
...Show More Authors

To determine the important pathogenic role of celiac disease in triggering several autoimmune disease, thirty patients with Multiple Sclerosis of ages (22-55) years have been investigated and compared with 25 healthy individuals. All the studied groups were carried out to measure anti-tissue transglutaminase antibodies IgA IgG by ELISA test, anti-reticulin antibodies IgA and IgG, and anti-endomysial antibodies IgA and IgG by IFAT. There was a significant elevation in the concentration of anti-tissue transglutaminase antibodies IgA and IgG compared to control groups (P≤0.05), there was 4(13.33%) positive results for anti-reticulin antibodies IgA and IgG , 3(10%) positive results for anti-endomysial antibodies IgA and IgG . There were 4 pos

... Show More
Publication Date
Sun Oct 22 2023
Journal Name
Iraqi Journal Of Science
Detection of Human Leukocyte Antigen and Celiac Disease Auto Antibodies in serum of Patients with Multiple Sclerosis
...Show More Authors

To determine the important pathogenic role of celiac disease in triggering several
autoimmune disease, thirty patients with Multiple Sclerosis of ages (22-55) years
have been investigated and compared with 25 healthy individuals. All the studied
groups were carried out to measure anti-tissue transglutaminase antibodies IgA IgG
by ELISA test, anti-reticulin antibodies IgA and IgG, and anti-endomysial
antibodies IgA and IgG by IFAT. There was a significant elevation in the
concentration of anti-tissue transglutaminase antibodies IgA and IgG compared to
control groups (P≤0.05), there was 4(13.33%) positive results for anti-reticulin
antibodies IgA and IgG , 3(10%) positive results for anti-endomysial antibodies

... Show More
View Publication Preview PDF
Publication Date
Thu Jun 30 2022
Journal Name
Iraqi Journal Of Science
Clinical and Histopathological Features of Ovarian Cancer in Iraq, Baghdad Between 2014-2020
...Show More Authors

     Ovarian cancer is a heterogeneous disease with disparities in clinical performance and consequences. It is a cluster of numerous subtypes with diverse biological topographies that cause alterations in response to treatments, relapse rates, and endurance. This task was designed to investigate the epidemiology of the diagnosed cases of ovarian cancer from 2014 to 2020 in Baghdad. A total of 51 cases of different ovarian cancer samples were collected from Al-Elwea Maternity Hospital and Medical City Teaching Hospital, Baghdad. Clinical information including patients' age, tumor size and location, pathological grade and stage were also collected. Results revealed high incidence of OC in patients at age of ˂55 years for the rate 59%

... Show More
View Publication Preview PDF
Scopus (11)
Crossref (1)
Scopus Crossref
Publication Date
Tue Jun 01 2021
Journal Name
Food Chemistry
Development of cellulose Nanofiber-based substrates for rapid detection of ferbam in kale by Surface-enhanced Raman spectroscopy
...Show More Authors

View Publication
Scopus (22)
Crossref (21)
Scopus Clarivate Crossref
Publication Date
Thu Dec 01 2022
Journal Name
Iraqi Journal Of Physics
Detection of Physical and Chemical Parameters Using Water Indices (NDWI, MNDWI, NDMI, WRI, and AWEI) for Al-Abbasia River in Al-Najaf Al-Ashraf Governorate Using Remote Sensing and Geographic Information System (GIS) Techniques
...Show More Authors

The purpose of this study was to find out the connection between the water parameters that were examined in the laboratory and the water index acquired from the examination of the satellite image of the study area. This was accomplished by analysing the Landsat-8 satellite picture results as well as the geographic information system (GIS). The primary goal of this study is to develop a model for the chemical and physical characteristics of the Al-Abbasia River in Al-Najaf Al-Ashraf Governorate. The water parameters employed in this investigation are as follows: (PH, EC, TDS, TSS, Na, Mg, K, SO4, Cl, and NO3). To collect the samples, ten sampling locations were identified, and the satellite image was obtained on the

... Show More
View Publication Preview PDF
Crossref (1)
Crossref
Publication Date
Thu Jan 24 2019
Journal Name
Al-kindy College Medical Journal
Role of MRI diffusion weighted imaging in differentiation between benign and malignant ovarian masses
...Show More Authors

Background: Characterization of the ovarian masses preoperatively is important to inform the surgeon about the possible management strategies. MRI may be of great help in identifying malignant lesion before surgery. Diffusion Weighted Imaging (DWI) is a sensitive method for changes in proton of water mobility caused by pathological alteration of tissue cellularity, cellular membrane integrity, extracellular space perfusion, and fluid viscosity.

Objective: to study the diagnostic accuracy of DWI in differentiation between benign and malignant ovarian masses.

Type of the study:Cross-sectional study.

Methods: this study included  53with complex

... Show More
View Publication Preview PDF
Crossref