Background: The association of celiac disease and type 1 diabetes mellitus is known worldwide due to shared auto immunological background, since celiac disease could present in diabetic patients with non specific symptoms or asymptomatically, periodic serological screening is necessary for early diagnosis.
Objectives: To estimate the prevalence of celiac disease in children with type 1 diabetes.
Patients and methods: A total of 152 children with type 1 diabetes attending the Children Welfare Teaching Hospital; 67 boys, 85 girls with mean age of 10.3 year± 3.7 and mean duration of diabetes 3.5years ±2.5, from May 2010 -May 2011 were screened for celiac disease using immunoglobulin A and G tissue transglutaminase (tTG) antibodies, immunoglobulin A endomysium antibody (EmA), and antiglutamic acid decarboxlase(Anti GAD) antibodies estimation.
Results: Anti tissue transglutaminase antibody was positive in 25 patients, more in girls (68%), duodenal biopsy was done for 15 patients, 13 had histological changes of celiac disease, making the prevalence of celiac disease 8.6%. The classical presentation of the disease was lacking in most patients, but they presented with short stature which was below the third percentile in 79% of patient with celiac disease. In most cases Celiac disease was diagnosed within the first year of the diagnosis of diabetes.
Conclusion: Annual autoantibody screening is recommended, for early diagnosis and management of patients with diabetes type 1.
Backgrounds: Despite advances in management of diabetes mellitus, it remains one of the major causes of morbidity and mortality, yet diabetic nephropathy is one of the main complications of diabetes mellitus. .Microalbuminuria is the beginning to the renal complications of diabetes mellitus; it is a significant index of early detection as well as monitoring the progression of diabetic nephropathy.
... Show MoreBackground: Type 1 diabetes mellitus is one of the most common chronic endocrine disorders of childhood, growth impairment is one of its long−term consequences
Objective: To study the anthropometric indices among children with type 1diabetes.
Results: A total of 253 children with type 1diabetes were studied, 51.8% were females, 47.9% developed the disease at 5-9 years of age, and 52.6% presented with classical signs and symptoms. Stunting /sever stunting was 15% with male predominance, higher among older age group (10-20 y), wasting/ sever wasting was 19.4% with male predominance, higher among older age group (10-20 y), over weight/ obese was 3.6% with females predominant an
pancreatic islets in which a process of programmed cell death (apoptosis) is elicited in the β-cells by interaction of activated T-cells and proinflammatory cytokines in the immune infiltrate. Interleukin-6 (IL-6) is a pleiotropic cytokine with a key impact on both immunoregulation and nonimmune events in many cell types .
Objective: to assess the level of serum IL-6 as an inflammatory marker in type 1 diabetic children, with correlation to FBG and HbA1c.
Subjects and methods: 45 type 1 diabetic child (20 males and 25 females), mean age 10.9± 3.4 years who attended the National Diabetic Center, Al-Mustansiria university were included in this study. 45 apparently healthy controls matched for age and sex were participated in this s
Background: type 1diabetes (T1DM) is a form of diabetes mellitus that results from autoimmune destruction of insulin-producing beta cells of the pancreas, leading to permanent insulin deficiency ,categorized as either being positive or negative for various auto antibodies related to pancreatic function .An anti glutamic acid decarboxylase autoantibody(Anti-GAD) is recognized as one of the major serological markers for type 1 diabetes mellitus.
Objectives: to determine the prevalence of the immunological marker (Anti-GAD) among a sample of type1diabetus mellitus patients and to identify some factors that might be associated with its seroposivity.
Method:
... Show MoreBackground: Type 1 diabetes mellitus (T1DM) is a common disease in childhood. A linear relation between glycemic control (HbA1c < 7) and onset or progression of complication was detected. Only few individuals achieve glycemic control.
Objective: To estimate the glycemic control among diabetic children attending tertiary center.
Methods: All diabetic children registered in the diabetic consultancy clinic in Children Welfare Teaching hospital (298) were included in the study. Case records were reviewed and information on demography, weight and height, age at diagnosis and HbA1c was requested.
Results: Out of the total, 23.8% diabetic children had glycemic control. Glycemic control was decreasing with age (p=0.001), significantl
Back ground: Celiac disease (CD) is an immune–mediated enteropathy induced by gluten with broad spectrum of presentation, many patients with atypical symptoms or clinically silent remain undiagnosed, and are at risk of long-term complications.
Objective: The aim of the present study is to determine the of prevalence celiac disease in children with short stature.
Patient and Methods: In this prospective study, 307 children 181(58.9%)males and 126(41.1%) females ,with ages ranging from 3 to 17.5years ( mean 12.2 ±3.4) with short statures (height below 3rd percentile adjusted for age and sex) attending the consultation room of endocrinology/ Welfare Teaching Hospital/medical city- Baghdad , were enrolled in this study from the firs
Background: Retinoblastoma is the most common intraocular tumor affecting young children.
Patients and Methods: A review of 32 children with retinoblastoma, diagnosed and treated at the Oncology Unit, Children Welfare Teaching Hospital, Medical City, Baghdad from 1999 to 2006.
Objectives: To review the clinical presentation and treatment outcome of retinoblastoma in children treated at the Children Welfare Teaching Hospital, Baghdad.
Results: Among 32 patients, 56.25% were males and 43.75% were females with a median age of 34.5 months. Unilateral disease was observed in 19 patients. Leukocoria was the most common presenting feature. Advanced s
... Show MoreBackground: Vitamin D and Leptin appears to play a range of roles in beta cell growth and insulin secretion and most importantly interaction with other hormonal mediators and regulators of energy and metabolism. Objective: The aim of this study was to measure serum leptin and vitamin D levels and to investigate their relationships with vitamin D and other clinical laboratory parameters in patients with type II diabetes. Subjects and Methods: Blood samples were taken from 80 patients with type II diabetes mellitus encountered during their attending the Internal Medicine clinic consultancy in Ramadi Teaching Hospital and the National Diabetes Center for Treatment and Research at Al-Mustansiriya University and 60 healthy subject. From Decem
... Show MoreBackground: Diabetic foot problems are one of the most important complications of diabetes mellitus
which causing a worldwide high cost morbidity which could be due to poor self-practices.
Objectives: To assess the preventive food care practices among diabetic patients and to find out any
significant association of these practices with selected socio-demographical and diabetic related
characteristics.
Patients and Methods: A descriptive cross-sectional study was conducted in Baquba city from the
period of 20th Septembers, 2016 up to 20th March, 2017, by selecting a sample of (120) patients by
using a structured questionnaire, the questionnaire composed of three parts, the first part contains
information related to