Background: Chronic leg ischemia commonly affects the arteries supplying the leg and mostly caused by atherosclerosis. Triplex ultrasound scanning is useful for delineating the anatomic site of disease in the lower limb in addition to the grading of the stenosis and evaluation of post-stenotic flow.

Objectives: To determine the extent of vasculopathy in patients with chronic leg ischemia by using triplex ultrasound scanning and match the sonographic findings with the clinical signs and symptoms.

Patients and methods: A cross sectional study from October 2009 to September 2010 was performed on 56 patients with clinical suspicion of chronic leg ischemia referring to ultraso

The study aimed to establish the association of miR-153-3p expression with treatment response to IM in CML patients. Sixty CML patients were included and divided into two groups consistent with their response to treatment whether sensitive or resistant to IM. Ten healthy normal participants were enrolled as control group. RNA was extracted from serum to work out miR-153-3p expression utilizing real-time quantitative reverse transcription polymerase chain reaction. The primers were supplied by Macrogen Inc. Twenty seven patients were sensitive to imatinib and 33 were resistant to imatinib. The ratio of male to female was 1.14:1. The bulk (58%) of patients were within the age range of 41-60 years. Weight and gender did not significantly diffe

Chronic myelogenous leukemia (CML) is a myeloproliferative neoplasm arises from Bcr-Abl gene translocation (called Ph chromosome) in hematopoietic stem cells (HSCs). This genetic abnormality results in constitutive activation of tyrosine kinase and subsequent uncontrol growth and multiplication of granulocytes. The cornerstone in treatment of CML are tyrosine kinase inhibitors, of which imatinib is the most effectively used. JAK2V617F mutation is an acquired single nucleotide polymorphism (SNP) occurs in JAK2 gene and is associated with many hematological malignancy other than CML. It was thought that the two genetic abnormalities (Bcr-Abl and JAK2V617F) occur mutually; however, growing body of evidences suggested the reverse. This study a

Background: Myringoplasty is a procedure used to seal(reconstruct) a perforated tympanic membrane using a graft material by underlay or overlay techniques . Temporalis fascia is the commonly used graft material.
Aim of study: to evaluate the difference in outcome of myringoplasty in cases of active and inactive chronic otitis media without cholesteatoma.
Patients and Methods: a prospective study of 54 cases of myringoplasty in adult age group whom age ranges from (20-40 years) and the duration of the disease ranges from (6-24 months). All patients were complaining of chronic otitis media without cholesteatoma assessed clinically, audiologically and radiologically, all cases operated under general anest

Background: High serum molybdenum level may contribute to dialysis related bone disease in patients requiring long term hemodialysis in fact massive molybdenum accumulation causes joint deformity and arthritis
Objective: To asses the level of molybdenum in uremic patients requiring long term hemodialysis and impact of hemodialysis on the serum level of molybdenum before and after hemodialysis
Patients and methods: Eighty patients complain from chronic renal failure on long term hemodialysis aged (16 to 65) years, serum molybdenum was measured before and after hemodialysis
Result: The mean serum molybdenum level in 80 patients requiring long term hemodialysis was elevated before dialysis (0.29 + 0.17 nmol/mL) and even after dialy

Chronic myelogenous leukemia (CML) is a myeloproliferative neoplasm arises from Bcr-Abl gene translocation(called Ph chromosome) in hematopoietic stem cells (HSCs).JAK2V617F mutation is an acquired singlenucleotide polymorphism (SNP) occurs in JAK2 gene and is associated with many hematological malignancyother than CML. This study aimed to investigate the prevalence of JAK2V617F mutation and serum levels ofalkaline phophatase (ALP) and lactate dehydrogenase (LDH) in Ph+ CML Iraqi patients treated with imatinib.Blood samples were collected from 42 Ph+ CML patients who have been received at least six month therapywith imatinib. DNA was extracted, and real time polymerase chain reaction (qPCR) was used for JAK2V617Fdetection. Serum levels of A

Background: Chronic Tonsillitis outcomes from frequent attacks of acute Tonsillitis usually for six attacks or more per year for two successive years. Poor dental hygiene had been associated with oro- pharyngeal problems and causes both dental caries and Tonsillitis alike.
Objective: To evaluate the relation between chronic Tonsillitis and severity of dental caries among 4-5 years old children.
Patients and Methods: Random sample of children was selected in Hospital of Baghdad medical city Otolaryngologic department city. Fifty-four children aged 4- 5 years old were participated in this study divided into two group: 29 children with Chronic Tonsillitis (study group) and 25 children with intact tonsils (control group). The determina

Background: Chronic obstructive pulmonary disease (COPD) is a preventable disease with some significant extra pulmonary effects that may contribute to the severity in individual patients.. The systemic manifestations  of  COPD  include  a number of endocrine disorders , such  as  those  involving the pituitary, the thyroid , the gonads, the adrenals  and  the pancreas.  The  mechanisms  by which COPD  alters  endocrine function are incompletely understood  but likely involve  hypoxemia , hypercapnia , systemic inflammation and  glucocorticoid  administration.

Objective:  To evaluate the relationship bet

Panax ginseng (PG), one of the most widely used herbal medicines, has demonstrated various beneficial effects such as anti-inflammatory, antioxidant, and anticancer impacts. Naturally occurring ginsenosides in the ginseng plant inhibit cell proliferation and significantly reduce liver damage induced by certain chemicals. Aflatoxin B1 (AFB1) is a primary mycotoxin due to its hepatotoxic, immunotoxic, and oncogenic effects in animal models and humans. In this study, we examined the effects of assorted doses of PG aqueous crude extract on the expression of matrix metalloproteinase 1 and 7 (MMP-1 and MMP-7) in the kidney, spleen, and liver of experimental AFB1-exposed mice, using immunohistochemistry (IHC). Mice were orally administered

Background: Heart failure is a complex clinical syndrome caused by any functional or structural cardiac disease that reduces the ventricle's ability to fill or pump blood. Anemia is frequent in patient with heart failure and is associated with deterioration through the activation of neuro-hormonal pathways. Dapagliflozin is a selective and reversible inhibitor of Sodium-glucose co-transporter-2 (SGLT2). Dapagliflozin increases hemoglobin level through different mechanisms such increasing plasma concentration by diuresis or increasing Erythropoietin synthesis.

Objective: To evaluate the effect of additional dapagliflozin into conventional therapy on hemoglobin in heart failure patients with chronic