Preferred Language
Articles
/
iqjmc-67
Correlation between the histopathological grade and size of breast cancer with axillary lymph node involvement
...Show More Authors

Background: Breast cancer account for 29% of all newly diagnosed cancer in female and is responsible for 14% of cancer related deaths in women. Breast cancer is basically detected either during a screening tests, before symptoms have appeared, or after a woman notices a mass. Overall risk doubles each decade until the menopause, when the increase slows down or remains stable.
Objective: to find the correlation between the tumor size and grade and involvement of axillary lymph node.
Patients and methods: a continuous prospective study of 50 patients from 1st January 2016 to 1st January 2017 in Baghdad teaching hospital at 1st surgical floor, where almost all patients with breast cancer operated on by modified radical mastectomy and axillary clearance included in the study.
Results: the commonest age group was 5th decade with 32% of patients followed by 6th decade with 28% of patients. The most common histological type was IDC with 78% and 22% of patients were ILC. The most common stage at presentation was stage II A with 32% of patients followed by stage III A with 28% of patients. Tumor size between (2-5)cm (T2) was the most common with 68% of patients. Grade II was the commonest histological grade in this study with 68% of patients. Axillary lymph nodes (ALN) involvement increase as tumor size increase, it was 50% in T1, 55.8% in T2, 88.8% in T3 and 100% in T4. Grade I associate with 25% +ve ALN, grade II 55.8% and 100% in grade III.
Conclusion: The majority of patients in this study were in fifth and sixth decades. There is delay in presentation of patients as evidenced by the most common tumor size being T2 and the most common stage being stage II A& stage III A.IDC was the most common histological type. The most common grade was grade II. The larger the tumor the more incidence of ALN involvement, also the higher grade of the tumor associate with more ALN involvement.

خلفية البحث: سرطان الثدي يمثل ۲۹% من مجموع حالات السرطان المشخصة حديثا في الاناث وهو مسؤول عن۱٤% من الوفيات الناجمة عن السرطان في النساء. وعادة ما يتم الكشف عن سرطان الثدي أما اثناء الفحص, قبل ظهور الأعراض , او بعد ان تلاحظ المرأة وجود تورمز الخطر الكلي للأصابة يتضاعف كل عشر سنوات حتى سن اليأس , عندها تتباطأ الزيادة او تبقى مستقرة.

الهدف من الدراسة: للعثور على العلاقة بين حجم الورم والدرجة النسيجية وتورط العقد اللمفاوية الأبطية.

المرضى وطريقة العمل: دراسة استطلاعية متواصلة من1 كانون الثاني 2016 الى 1 كانون الثاني 2017 في مستشفى بغداد التعليمي , الطابق الجراحي الأول , حيث تم شمول تقريبا كل المرضى الذين يعانون من سرطان الثدي الذين أجري لهم أستئصال الثدي مع تنظيف الأبط .

النتائج: كانت الفئة العمرية الأكثر شيوعا هي العقد الخامس بنسبة 32% من المرضى تليها العقد السادس بنسبة 28% من المرضى. كان النوع النسيجي القنوي الأكثر شيوعا بنسبة 78% وكانت نسبة 22% من المرضى من النوع الغدي. وكانت المرحلة الأكثر شيوعا هي المرحلة 2 بنسبة 32% من المرضى تليها المرحلة 3 بنسبة 28% من المرضى. وكان حجم الورم بين (5-2)سم الأكثر شيوعا بنسبة 68% من المرضى. كانت الدرجة النسيجية 2 هي الأكثر شيوعا بنسبة 68%. تورط العقد اللمفاوية يزداد بأزدياد حجم الورم والدرجة النسيجية فهو 50% في T1 و 55.8% في T2 و 88.8% في T3 و 100% في T4. وكانت نسبة تورط العقد اللمفاوية 25% في الدرجة النسيجية 1 و 55.8% في الدرجة النسيجية 2 و 100% في الدرجة النسيجية 3.

الاستنتاج: الاغلبية في هذه الدراسة تتراوح اعمارهم بين العقد الخامس والسادس. هناك تاخير واضح للمرضى في الحضور لغرض الكشف عن المرض حيث ان اغلبية حجم المرض هو  تي 2   والمرحلة الشائعة للمرض هي الثانية اي  واغلبية الفحص النسيجي هي سرطان داخل القناة الخبيث واغلبية رتبة الورم النسيجية هي الرتبة الثانية وكلما زاد حجم الورم زادت معه قابلية اصابة الغدد اللمفاوية الابطية وكذلك كلما زادت رتبة الورم النسيجية زادت معه قابلية اضابة الغدد اللمفاوية الابطية بشكل اكبر.   

Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Sun Apr 01 2007
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Correlation between the conventional, routine histological grading of transitional cell carcinoma of the urinary bladder and morphometric analysis
...Show More Authors

Background: Transitional cell carcinoma of the urinary bladder is one of the important malignancies in both sex groups .It is considered as a heterogenous neoplasm with different
biological behavior, in which the majority are early non invasive with tendency for recurrence and some may progress to invasive tumor. An important clinicopathological features are ,the tumor stage and histological grade which are used as prognostic parameters of the tumor and play an important role in therapy. Due to the subjectivity of the histological grading , the reproducibility was low . Many studies showed the value of quantitative analysis of the tumor as an important method in determining the recurrence of the tumor and

... Show More
View Publication Preview PDF
Crossref
Publication Date
Wed Jan 06 2021
Journal Name
Pierm
ULTRA-WIDEBAND FEATURING ENHANCED DELAY AND SUM ALGORITHM AND ORIENTED FOR DETECTING EARLY STAGE BREAST CANCER
...Show More Authors

Abstract—In this study, we present the experimental results of ultra-wideband (UWB) imaging oriented for detecting small malignant breast tumors at an early stage. The technique is based on radar sensing, whereby tissues are differentiated based on the dielectric contrast between the disease and its surrounding healthy tissues. The image reconstruction algorithm referred to herein as the enhanced version of delay and sum (EDAS) algorithm is used to identify the malignant tissue in a cluttered environment and noisy data. The methods and procedures are tested using MRI-derived breast phantoms, and the results are compared with images obtained from classical DAS variant. Incorporating a new filtering technique and multiplication procedure, t

... Show More
Publication Date
Fri Feb 08 2019
Journal Name
Journal Of The College Of Education For Women
Minimum Spanning Tree Algorithm for Skin Cancer Image Object Detection
...Show More Authors

This paper proposes a new method Object Detection in Skin Cancer Image, the minimum
spanning tree Detection descriptor (MST). This ObjectDetection descriptor builds on the
structure of the minimum spanning tree constructed on the targettraining set of Skin Cancer
Images only. The Skin Cancer Image Detection of test objects relies on their distances to the
closest edge of thattree. Our experimentsshow that the Minimum Spanning Tree (MST) performs
especially well in case of Fogginessimage problems and in highNoisespaces for Skin Cancer
Image.
The proposed method of Object Detection Skin Cancer Image wasimplemented and tested on
different Skin Cancer Images. We obtained very good results . The experiment showed that

... Show More
View Publication Preview PDF
Publication Date
Sun Jul 30 2023
Journal Name
Iraqi Journal Of Science
Cytotoxic Activity of Ephedra alata Extracts on Human Lymphocytes and Breast Cancer Cell Line in Vitro
...Show More Authors

     This study was conducted to use the local Ephedra alata plant as a model for extracting and detecting alkaloids in the stem of plant (alkaloids-rich extract and crude extract). Different extraction procedures were adopted for qualitative as well as the quantitative examination of the alkaloid extracts, as well as plant crude extract, the best methods for the extraction of the plant materials were applied. Simple, fast and accurate methods like TLC (thin layer chromatography) and HPLC (High-performance liquid chromatography), were used for the identification of the alkaloids (ephedrine) in different extracts of stems E. alata stems. Ephedrine alkaloid was detected in each alkaloids-rich and crude extrac

... Show More
View Publication Preview PDF
Scopus Crossref
Publication Date
Sun May 30 2021
Journal Name
Iraqi Journal Of Science
A correlation study between hyperthyroidism and some apoptosis markers among Iraqi patients
...Show More Authors

This study was carried out in the Center of Endocrinology and Diabetes in Baghdad during the period between October 2019 to February 2020. The aim was to measure the level of some apoptosis markers and some autoimmune antibodies related to the thyroid gland in Iraqi patients with hyperthyroidism and evaluate the correlation between all the measured parameters. The study included 88 patients who were divided into three groups; group 1 included 30 newly diagnosed hyperthyroidism patients (24 females, 6 males); group 2 included  30 patients of hyperthyroidism who were under treatment (28, 2 males); group 3 included 28 healthy individuals as control group (22 females, 6 males).

     Most of the patient's ages

... Show More
View Publication Preview PDF
Scopus (4)
Crossref (1)
Scopus Crossref
Publication Date
Mon Mar 23 2020
Journal Name
International Journal Of Nanoscience
Gold Nanoparticles Synthesis Using Environmentally Friendly Approach for Inhibition Human Breast Cancer
...Show More Authors

In this study, gold nanoparticles were synthesized in a single step biosynthetic method using aqueous leaves extract of thymus vulgaris L. It acts as a reducing and capping agent. The characterizations of nanoparticles were carried out using UV-Visible spectra, X-ray diffraction (XRD) and FTIR. The surface plasmon resonance of the as-prepared gold nanoparticles (GNPs) showed the surface plasmon resonance centered at 550[Formula: see text]nm. The XRD pattern showed that the strong four intense peaks indicated the crystalline nature and the face centered cubic structure of the gold nanoparticles. The average crystallite size of the AuNPs was 14.93[Formula: see text]nm. Field emission scanning electron microscope (FESEM) was used to s

... Show More
View Publication
Scopus (4)
Crossref (3)
Scopus Clarivate Crossref
Publication Date
Sun Apr 24 2022
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Prevalence of Lung Cancer in Al Najaf Governorate Registered in Middle Euphrates Oncology Center during 2019 and 2020
...Show More Authors

Background: Lung cancer is a disease in which cells in the lung grow out of control and may spread to lymph nodes or other organs in the body such as the brain. Cancer from other organs also may spread to the lungs. The chance that a man will develop lung cancer in his lifetime is about 1 in 15; for a woman, the risk is about 1 in 17. These numbers include both people who smoke and those who don't smoke. Worldwide; prevalence of the lung cancer was decreased in the last decade.

Objectives: To determine the prevalence of lung cancer in Al Nagaf Governorate during 2019 and 2020

Patients and Methods:

A Registry-based cross sectional study was conduct

... Show More
View Publication Preview PDF
Crossref
Publication Date
Sun Jul 31 2022
Journal Name
Iraqi Journal Of Science
Deep Learning and Machine Learning via a Genetic Algorithm to Classify Breast Cancer DNA Data
...Show More Authors

       This paper uses Artificial Intelligence (AI) based algorithm analysis to classify breast cancer Deoxyribonucleic (DNA). Main idea is to focus on application of machine and deep learning techniques. Furthermore, a genetic algorithm is used to diagnose gene expression to reduce the number of misclassified cancers. After patients' genetic data are entered, processing operations that require filling the missing values using different techniques are used. The best data for the classification process are chosen by combining each technique using the genetic algorithm and comparing them  in terms of accuracy.

View Publication Preview PDF
Scopus (8)
Crossref (3)
Scopus Crossref
Publication Date
Mon Jan 30 2023
Journal Name
Iraqi Journal Of Science
Cytotoxic Effect of the Alcoholic Extract of Conocarpus erectus Leaves on MDA-MB 231 and MCF7 Breast Cancer Cell Lines
...Show More Authors

    Currently, there is a growing interest in medicinal plants extracts as some plants have shown antitumor potential. The goal of this study was to test the anticancer activity of methanol extract of Conocarpous erectus leaves in breast cancer cells.  Cytotoxicity was tested in vitro on breast cancer cell lines, MCF7 [Estrogen receptor + (ER+)] and MDA-MB231 [Estrogen receptor - (ER-)], in addition to normal fibroblast cells (REF). MTT assay was utilized to measure the growth inhibitory effects after 48 hours exposure to extracts.  Viability results indicated  that MDA-MB231 were sensitive (GI50 = 56.1µg/ml).However, no sensitivity was seen in both MCF7 and REF cells (GI50>100 µg/ml). I

... Show More
View Publication Preview PDF
Scopus (1)
Scopus Crossref
Publication Date
Sun Apr 03 2016
Journal Name
Journal Of Educational And Psychological Researches
The effect of the differences in the correlation pattern of the micro blogging in the educational attainment of computer science curriculum for 12th grade students
...Show More Authors

The object of this research is to determine the effect in the differences of the correlation pattern of the micro blogging on the educational attainment of computer science curriculum for 12th grade students. I will try to test the best suited correlation and I might use the demo curriculum as well to achieve its objectives , The research method that will be used in this research is the quantitative method where we will use a sample of 60 students divided into two groups ( correlate the micro blogging - adopted the sequence pattern of relating the micro blogging) As a result, we found out that there are quantitative differences among the two groups' median , The differences goes back to the main effect of the correlation pattern of the m

... Show More
View Publication Preview PDF