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A Comparison of Three Different Treatment Regimens of HCV Infection in295 Iraqi Patients
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Background:  Viral Hepatitis C infection is global public health problem throughout the world. Different
treatment regimens are used which produce different rates of response affected by many factors.
Objectives: To assess the efficacy of three different treatment regimens in 295 Iraqi patients infected with
chronic HCV.
Patients and methods: This is an observational cohort study; in which 295 (133 male and 162 female) patients with chronic HCV infection were enrolled during the period between August 2015 to January 2017
from Gastroenterology clinic of Baghdad Teaching Hospital and Gastroenterology and Hepatology Teaching
Hospital. Baseline HCV viral load measurements and genotyping were done for each patient. Patients were
followed up by viral load measurement at end of the treatment period and three months after the end of the
treatment.
Results: The majority of patients infected with chronic HCV achieved sustained virological response(SVR)
(defined as undetectable HCV RNA 12 to 24 weeks after the end of the treatment); were of the generic(  sofosbuvir/ledipasvir) treatment group (51out of 72 (70.8% ) followed by generic Sofosbuvir with (peg  interferon/ribavirin)treatment group (68 out of 111 (61.3%) followed by (peg interferon/ribavirin)  treatment
group (42 out of 86 ( 48.8%).
Conclusions: The best treatment efficacy was obtained with generic sofosbuvir/ledipasvir followed by
sofosbuvir with peg interferon and ribavirin then peg interferon and ribavirin. The most responder genotype
in Iraqi patients was genotype 4 and the least responder genotype was genotype 1b
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Publication Date
Sun Apr 05 2015
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Predictors of Response to (Etanercept) in the Treatment of Iraqi Patients with Active Rheumatoid Arthritis
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Background: Since the introduction of tumour necrosis factor-alpha (TNF-α) inhibitors including etanercept, their efficacy and safety in treatment of rheumatoid arthritis (RA) have been studied in many randomized controlled clinical trials. However, data regarding predictors of clinical response to anti-TNF therapy are still sparse.
Objective: To assess the predictors of response to etanercept in treatment of Iraqi patients with active RA.
Methods: An open label single group prospective study was conducted over 15 months on 190 Iraqi patients with RA. All the included patients were given etanercept at a dose of 50 mg by subcutaneous injection on
a weeklybases. Each patient was followed at regular intervals of bas

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Publication Date
Mon Feb 14 2022
Journal Name
Journal Of Educational And Psychological Researches
Comparison between Rush Model Parameters to Completed and Lost Data by Different Methods of Processing Missing Data
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The current study aims to compare between the assessments of the Rush model’s parameters to the missing and completed data in various ways of processing the missing data. To achieve the aim of the present study, the researcher followed the following steps: preparing Philip Carter test for the spatial capacity which consists of (20) items on a group of (250) sixth scientific stage students in the directorates of Baghdad Education at Al–Rusafa (1st, 2nd and 3rd) for the academic year (2018-2019). Then, the researcher relied on a single-parameter model to analyze the data. The researcher used Bilog-mg3 model to check the hypotheses, data and match them with the model. In addition

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Publication Date
Wed Mar 10 2021
Journal Name
Baghdad Science Journal
Serum Protein Profile Of Iraqi Hydatidosis Patients with Different Sites of Infection
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Blood samples of One hundred and twenty patients from different hospitals in Baghdad infected with hydatidosis in different sites of the body (Liver, Lung, multiorgans and kidney) were collected for this study. On the other hand, 30 healthy individuals were included as a control group. This study was conducted to evaluate the effect of this disease on the serum protein profile of the patients using electrophoresis. The results revealed four different protein banding patterns with difference in number of bands and their molecular weights in comparison to the control group, and these differences depended on the site of infection. However the data showed a presence of the same band in all patients with different site of infection.

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Publication Date
Sun Jul 03 2011
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Serum levels of cytokines (TNF-α, IFN-γ& IL-10) in Type-2 diabetic patients with HCV infection
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Back ground: Type 2 Diabetes mellitus (T2D) is a common complication of all liver diseases. However clinical and experimental data suggest a direct role of HCV in the perturbation of glucose metabolism. The aim of this study is to investigate the role of HCV infection as a risk factor to develop type 2 diabetes mellitus, and to study the immunopathogenicity of HCV in diabetes mellitus patients, through the assessment of IFN-γ, TNF- α and IL-10 serum levels.
Objectives: Is to investigate the role of HCV infection as a risk factor to develop type 2 diabetes mellitus, and to study the immunopathogenecity of HCV in diabetes mellitus patients, through the assessment of IFN-γ, TNF- α and IL-10 serum levels.

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Publication Date
Wed Jul 01 2015
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Experimental Study the role of LasA Protease of Pseudomonas aeruginosa in the Treatment of Bacterial Keratitis Caused by Staphylococcus aureaus
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Background: LasA protease play a major role in the colonization of the bacteria to the cornea during bacterial keratitis by preventing other bacteria from colonization to the cornea, for example in the mixed infection with S. aureus the enzyme eradicate the bacteria by their lysis it and finally eliminate the competitive for P. aeruginosa bacteria.
Objective: To study the role of LasA protease of Pseudomonas aeruginosa in the treatment of experimental keratitis caused by S. aureus.
Patients and methods: One hundred - twenty clinical samples (corneal scraping) were collected from patients suspected with bacterial keratitis presenting to Ibn Al-Haitham Teaching Hospital from May 2013 until November 2013. The bacterial isolate of P. a

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Publication Date
Mon Oct 01 2012
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Validity and reliability of CDAI in comparison to DAS28 in Iraqi patients with active rheumatoid arthritis
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Background: Rheumatoid arthritis (RA) disease activity plays a central role in causing disability both directly and via indirect effects mediated through joint damage. Evaluation of RA disease activity is therefore important to predict the outcome and effectiveness of therapeutic interventions during follow-up. Clinical disease activity index (CDAI) is new simple tool for measurement of disease activity.
Objectives: To assess validity and reliability of CDAI in comparison to disease activity score-28 joints (DAS28) in Iraqi patients with active RA.
Patients and Methods: Sixty nine Iraqi RA patients were included in this study. All patients were fulfilling the ACR classification criteria and active. Full history was taken and comple

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Publication Date
Wed Jun 30 2021
Journal Name
Journal Of Economics And Administrative Sciences
A Comparison between robust methods in canonical correlation by using empirical influence function
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       Canonical correlation analysis is one of the common methods for analyzing data and know the relationship between two sets of variables under study, as it depends on the process of analyzing the variance matrix or the correlation matrix. Researchers resort to the use of many methods to estimate canonical correlation (CC); some are biased for outliers, and others are resistant to those values; in addition, there are standards that check the efficiency of estimation methods.

In our research, we dealt with robust estimation methods that depend on the correlation matrix in the analysis process to obtain a robust canonical correlation coefficient, which is the method of Biwe

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Publication Date
Wed Aug 30 2023
Journal Name
Baghdad Science Journal
Hepatocellular Carcinoma Prediction and early Diagnosis of Hepatitis B and C viral infection using miR-122 and miR-223 in a sample of Iraqi patients.
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Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death. Therefore, it is critical for researchers to understand molecular biology in greater depth.  In several diseases including cancer, abnormal miRNA expression has been linked to apoptosis, proliferation, differentiation, and metastasis. Many miRNAs have been studied in relation to cancer, including miR-122, miR-223, and others. Hepatitis B and C viruses are the most important global risk factors for HCC. This study is intended to test whether serum miRNAs serve as a potential biomarker for both HCC and viral infections HBV and C. The expression of miRNA in 64 serum samples was analyzed by RT-qPCR. Compared to healthy volunteers, HCC patients' sera expre

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Publication Date
Sun Apr 24 2022
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Cephalosporins are the not the cause of death in a pregnant with urinary tract infection; A case Report: Cephalosporins and treatment of urinary tract infection during pregnancy
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Background: Urinary tract infection is a highly prevalent disease all over the world and affects females more than males. In the former, it may complicate pregnancy to potentially lethal septicaemia. Therefore, the aim of current case report was to show how misinterpretation of symptoms of septicaemia can lead to inadequate, and probably inappropriate, management with subsequent medico-legal consequences. Methods: A case study of a young pregnant female who developed urinary tract infection and treated with parenteral cephalosporins. The infection developed into septicaemia with subsequent miscarriage and death of the patient. Discussion: Misinterpretation of the symptoms of septicaemia

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Publication Date
Fri Oct 12 2018
Journal Name
International Journal Of Medical Research & Health Sciences
A Comparison of Fear Levels of Endodontic Treatment in Iraqi Population
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Introduction: Dental fear is defined as the patient’s specific reaction towards stress related to dental treatment in which the stimulus is unkn..

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