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Resistance of anti-tuberculosis drugs among pulmonary tuberculosis patients in Yemen
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Background: Tuberculosis (TB) is still a major global public health problem worldwide. The global prevalence of Mycobacterium (M tuberculosis) infection has been estimated in 32% of the world population with more than 8 million new cases diagnosed each year.

Materials and Methods: A total of 192 M tuberculosis complex isolates were collected from patients with positive sputum smear who had been treated previously with the four main anti- tuberculosis drugs for more than two months. The isolates were identified by their colonial morphology, pigmentation, shapes on Ziehl-Neelsen smears, growth on Löwenstein-Jenson medium and biochemical tests as niacin and nitrate tests. A proportional method was used for the in vitro drug susceptibility testing.Objective: To estimate drug resistance among previously treated tuberculosis patients, focusing on multi-drug resistant strains at two time intervals (2002 and 2009) in Yemen.

Results: Of the 192 M tuberculosis complex tested isolates, 55 (28.7%) were resistant to one or more drug; 20 (10.4%) were resistant to one drug, 13 (6.8%) to two drugs, 13 (6.8%) to three drugs and 9 (4.7%) to four drugs. Regarding the resistance to an individual drug, out of 192 tested isolates, 36 (18.7%) were resistant to rifampicin, 34 (17.7%) to isoniazid, 33 (17.2%) to ethambutol and 18 (9.4%) to streptomycin and these results were without a statistical significance. The incidence of multidrug resistance against rifampicin and isoniazid with or without other drugs was 13.5% among the tested M tuberculosis complex strains and this result was also without a statistical significance.

Conclusion: The results of this study revealed nearly similar drug resistance patterns for the tested isolates in comparison with previous findings of 2002 and the emergence of more multi-drug resistance M tuberculosis complex strains after a time interval in Yemen.

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Publication Date
Sat Feb 01 2020
Journal Name
Meta Gene
Interleukin-2 serum level, genetic polymorphism (rs2069763), anti-rubella antibody and risk of multiple sclerosis among Iraqi patients
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Background: Multiple sclerosis (MS) is a chronic neurodegenerative autoimmune disease mediated by autoreactive T cells against myelin-basic proteins. Cytokines are suggested to play a role in the etiopathogenesis of the disease. Among these cytokines is interleukin-2 (IL-2). Aim of the study: To investigate the association between IL2+166 G/T single nucleotide polymorphism (SNP: rs2069763) and MS in Iraqi patients. Serum level of IL-2 was also detected. Anti-rubella IgG antibody was further determined in the sera of patients. Patients and methods: Eighty MS patients (28 males and 52 females; age mean ± SD: 39.2 ± 16.1 years) and 80 healthy control matched patients for age (32.15 ± 16.13 years) and gender (28 males and 52 females) were en

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Publication Date
Tue Oct 05 2021
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Association between HbA1c and dyslipidemia among sample of Iraqi Patients with Type2 DM
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Background: Diabetic Mellitus is considered as a public health concern. More than 8 percent of the United States has diabetes. Diabetes is a serious risk factor for Atherosclerotic cardiovascular disease (ASCVD) and an important cause of mortality. ASCVD is the commonest cause of death in the Western world. Diabetes was defined as a high risk condition for ASCVD. In adults with diabetes with ASCVD or multiple ASCVD risk factors it is important to prescribe high intensity statin to reduce LDL at least to 50%.

Objective: To investigate association between dyslipidemia and HbA1c and to detect benefit of using some statins in decreases the risk of CVD.

Material and method: A

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Publication Date
Wed Apr 15 2020
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Antimicrobial resistance patterns of Acinetobacter baumannii colonization patients skin
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Background: Acinetobacter baumannii is a significant opportunistic pathogen and it is generally associated with benign colonization of hospitalized patients.

Objective: To investigate skin colonizationwith Acinetobacter baumannii in hospitalized patients and healthy volunteers.Antimicrobial resistance patterns of Acinetobacter baumanniiwas assessed by determining the minimum inhibitory concentrations (MICs) of thirteen different antimicrobial agents.

Patients and Methods: The study performed on hospitalized patients at Rizgary and Hawler teaching hospitals and healthy volunteers who attended to supermarkets in Erbil, Iraq. A single sample was ob

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Publication Date
Sat Sep 23 2023
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Effect of pharmacist interventions on pulmonary function parameters of Iraqi asthmatic patients: A comparative study: Effect of pharmacist interventions on pulmonary functions tests
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Background: Despite the fact that asthma is a long-term disease that may be treated, many people are unable to control their symptoms due to a lack of knowledge about their condition. The study's purpose was to find out if a pharmacist intervention improved asthma management because of this.

Objective: this study designed to assess the effect of pharmaceutical care on pulmonary functions test.

Method: The study was completed in three months. The patients who were enrolled were divided into two groups: Group 1 consists of 23 asthma patients who were randomly assigned to receive conventional therapy for chronic bronchial asthma based on disease stage and se

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Publication Date
Sun Oct 02 2011
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Electrophysiologic Study of Cognitive Functions in Epileptic Patients
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Background: Cognitive dysfunctions in epileptic patients may develop due to the neurophysiologic changes related to seizures or antiepileptic drugs.
Objectives: The aim of this longitudinal study was to evaluate the cognitive dysfunction in epileptic patients under antiepileptic drug therapy by the aid of event related potentials.
Patients & Method: P300 latencies were obtained from Fz, Cz and Pz electrodes positions from both epileptic patients (n = 224) and age and sex matched control group (n = 91). Epileptic patients were classified either having partial epilepsy, generalized epilepsy or both partial and generalized epilepsy (combined epilepsy). EEG and p300 test repeated for each patient every three months for one year. Th

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Publication Date
Tue Apr 01 2014
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Hepatitis G virus infection among Iraqi patients on maintenance hemodialysis
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Background: Patients on maintenance hemodialysis are at increased risk of infection with parentally transmitted viral agents. In recent years a high prevalence of hepatitis G virus infection among end stage renal diseases and chronic hemodialysis patients has been well documented.
Objectives: To assess the percentage and risk factors of HGV in hemodialysis patients, and to evaluate the clinical consequences of HGV in this population.
Patients and methods: Fifty (50) patients with chronic renal failure who underwent maintenance hemodialysis. Patients were currently attending hemodialysis department of Baghdad teaching hospital during the period of October 2011 to January 2012, compared to forty one (41) healthy blood donors who unde

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Publication Date
Sun Jul 01 2018
Journal Name
Current Research In Microbiology And Biotechnology
Detection of anti-Helicobacter pylori in patients with Multiple Sclerosis
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To determine the relationship between Helicobacter pylori infection and Multiple Sclerosis (MS) disorder, 20 patients with MS aged (25-60) years have been investigated from the period of 2016/12/1 to 2017/3/1 and compared to 15 apparently healthy individuals. All study groups were carried out to measure anti H.pylori IgA and H.pylori IgG antibodies by enzyme linked immunosorbent assay (ELISA) technique. There was a significant elevation (p<0.05) in the concentration of anti H.pylori IgG and IgA antibodies (Abs) compared to control group, and there was no significant difference (p>0.05) in the concentration of IgA and IgG (Abs) of H.pylori according to gender, and there was no significant difference (p>0.05) in the concentration of IgA and I

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Publication Date
Sun Oct 01 2017
Journal Name
Journal Of Educational And Psychological Researches
Existential frustration and its relation with recrimination among university students
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The study aims to identify the level of existential frustration and the level of recrimination among the students of universities, identify the statistical differences between the existential frustration and recrimination based on gender, and finally, identify the correlation between the existential frustration and recrimination. To do this, the researcher adopted the existential frustration scale of ( al-saaedi, 2009) that consisted of (43) item, he also adopted the recrimination scale of ( al-zugeibi,2008) which composed of (31) item. The total sample was (120) male and female student were chosen randomly from four colleges within the university of Baghdad for the academic year ( 2015-2016). The results revealed that the targeted sampl

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Publication Date
Fri Feb 08 2019
Journal Name
Iraqi Journal Of Laser
Effect of Laser Surface Modification on the Corrosion Resistance of Dental Alloys in Artificial Saliva Containing Alcoholic Beverages
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The objective of this study is to demonstrate the corrosion behavior of dental alloys Co-Cr-Mo, Ni-Cr-Mo and Ti-Al-V in artificial saliva at pH=4 and 37oC enriched with ethyl alcohol at 8% percentage. The linear and cyclic polarizations were investigated by electrochemical measurements. Laser surface modification was achieved for the three dental alloys to improve corrosion resistance. The results show that corrosion resistance of Co-Cr-Mo and Ni-Cr-Mo alloys only were increased after laser treatment due to the fact that laser radiation has caused a smoother surface, in addition to the decrement in corrosion current densities (icorr) for Co-Cr-Mo and Ni-Cr-Mo alloys and the reverse scan in cyclic polarization became in the wider range of

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Publication Date
Sun Jan 03 2016
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Evaluation of Serum Apelin in Acute Coronary Syndrome Patients
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Background: Acute coronary syndrome refers to any group of clinical symptoms compatible with acute myocardial ischemia including unstable angina (UA), Non-ST-segment elevation myocardial infarction (NSTEMI) & ST-segment elevation myocardial infarction (STEMI).
Apelin is a novel endogenous peptide with inotropic and vasodilatory properties, it was recently reported that serum measurements of apelin were similar to its immunohistochemical data in vessels and heart tissues.
Objectives: This study aims to evaluate serum levels of apelin in patients with Acute Coronary Syndrome related to severity of presentation.
Patients and Methods: The present study was conducted during the period from September 2014 until March 2015. Fifty-n

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