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Effect of doxorubicin on the histological structure of the kidneys in male albino rats
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Background:  doxorubicin is one of the most active cytotoxic agents in current use, it has a very potent effect in the treatment of various malignancy either used alone or combined with other cytocidal agents, the antitumor activity of this drug associated with cytotoxic effect such as cardiotoxicity, hepatotoxicity,  nephrotoxicity, myelosuppression.

Objectives: - this study was designed to investigate the effect of the doxorubicin on the histological structure of the rats' kidney.


Results:
  -  Doxorubicin cause reduction in the body weight and changes in the histological structure of the kidney which are atrophy of some  glomeruli with widening of the urinary space between the glomerular tuft and the bowman's capsule , other glomeruli show expansion of glomerular tuft with obliteration of the urinary space, degenerative changes in the tubular epithelium, increase rate of apoptosis, necrosis, cystic changes of the tubules and vacuolation of the tubular epithelial cells cytoplasm, protein cast formation in the tubular lumen, infiltration of inflammatory cells in the interstitium, proliferation of collagen fibers(fibrosis) in the interstitium and glomerulosclerosis, the follow up animals show persistence and more extensive lesion than group B.

Patients and  Methods:- one of the most important cytotoxic effect of doxorubicin is nephrotoxicity. Therefor sixteen adult male Wister albino rats have been used in this study, Eight of them were given 1 ml of intraperitoneal injection of normal saline alone daily for six consecutive days and served as a control group (A), The other Eight rats were given intraperitoneal dose of (1mg/kg body weight) doxorubicin, daily for six consecutive days and served as treated group (B), tow animals from group B kept alive without treatment for another week (observation period) as follow up animals to see the reversibility of the renal injury that are caused by doxorubicin. the animals were sacrificed at the end of the experiment, The body weight of the animals were recorded before starting the injection and recorded again just before killing the animals to see the changes in the body weight and the kidney sections were prepared and stained with hematoxylin and eosin stain, Periodic acid Schiff ̓s reagent (PAS), Orcin VanGieson stain, and examined by light microscope.

Conclusion:  doxorubicin causes marked changes in the normal histological architecture of the rats' kidney, and these changes are irreversible after cessation  of  doxorubicin injection (observation period).

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Publication Date
Fri Dec 15 2023
Journal Name
Bionatura
Evaluation of the Drinking water in some Hospitals in Baghdad
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Due to the significance of hospital drinking water, a study was done to assess the water in three hospitals in Baghdad (Al-Yarmouk Teaching Hospital, Ibn Sina Hospital, and Ibn-Al-Nafis Hospital) for its nature and quality, compare it to other hospitals in terms of its physical, chemical, and bacterial specifications, and compare it to international standards. According to Iraqi standards from 2009 and WHO standards from 2011, Chemical factors were measured, which included pH, Total Dissolved Solids (TDS), and Calcium Ion (Ca+2). Reported readings are all within acceptable ranges for drinking water. In contrast, turbidity, total hardness (T.H.), chlorides (Cl-), magnesium (Mg+2), the number of aerobic plates (APC), total coliform (T

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Publication Date
Sun Sep 04 2016
Journal Name
Baghdad Science Journal
Survey of Keratinophilic Fungi in the Tigris River in Baghdad
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The present study includs the isolation and identification of Keratinophilic fungi in fresh water samples collected from Tigris river in Baghdad, Iraq. Samples were collected from different districts of Baghdad (Al-Rustumia, Madina Al-Teb, Al-Azamia, Al-Kadimia, Al-Dorha and Al-Kanah). The water samples were examined for keratinophilic fungi by the plating method culturing and Hair Baiting Technique. A total number of 18 genera are recorded, in which the Tigris water indicates an impressive diversity of fungi. A variety of fungal strains were isolated from river water, out of 814 fungal colonies, Aspergillus terrus (5.5%) was the most frequent species, followed by Asperg

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Publication Date
Mon Jul 31 2017
Journal Name
Journal Of Engineering
The Role of Patnership Approuch in Facilitating Housing in Iraq
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Publication Date
Thu Dec 28 2017
Journal Name
Al-khwarizmi Engineering Journal
Mathematical Modeling of Glucose Regulation System in Term of Perturbed Coefficients
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In this research a recent developed practical modeling technique is applied for the glucose regulation system identification. By using this technique a set of mathematical models is obtained instead of single one to compensate for the  loss of information caused by the optimization technique in curve fitting algorithms, the diversity of members inside the single set is interpreted in term of restricted range of its parameters, also a diagnosis criteria is developed for detecting any disorder in the glucose regulation system by investigating the influence of variation of the parameters on the response of the system, this technique is applied in this research practically  for 20 cases with association of  National Center for

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Publication Date
Mon Feb 01 2016
Journal Name
Al-academy
Unconventional materials in the contemporary sculptural composition: علاء محسن كَبيّش
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This study aimed to knowledge of the effects of the Traditional ore upon the structure of sculpture form, as well as to knowledge of new materials that was used for the contemporary sculpture. This study included four chapter: first chapter was specialized for methodical frame. such as problem of research. that it was abstracted by question about the reason that lead the sculptor to search from new raw to carry out his sculpture works? As well as the important of research and its limits was that define between year 1950 up to 2000. The second chapter included the theoretical field and previous studies, that formed from three researches, such as the fist about the materials, as it was considered master element at the sculpture formal. the

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Publication Date
Wed Sep 30 2015
Journal Name
College Of Islamic Sciences
Fundamentalist detective On matters of consensus   Of Khala book complete the teacher benefits of Muslim Judge Ayaz (May God have mercy on him): Comparative fundamentalist study
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Fundamentalist detective
On matters of consensus
  Of Khala book complete the teacher benefits of Muslim
Judge Ayaz
(May God have mercy on him)

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Publication Date
Thu Jun 15 2023
Journal Name
Journal Of Legal Sciences
The Historical Context of Migration in Morocco to Europe: from Forced Migration to Irregular Migration : Study in International Law
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Considering that migration is moving to live from one place to another, with an intention in the place that was intended for a long time, due to the frequent movement of individuals from one place to another, and due to the different purpose of migration, we find external migration classified into legalized and irregular migration, and the reasons The growth of illegal immigration is due to economic,  social, and psychological motives, and therefore we find that it has multiple effects, both on the country hosting immigrants in terms of economic, security, social and health terms, or on the level of organizing international relations between countries, so countries sought to mitigate this phenomenon and deal with immigrants As stipu

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Publication Date
Fri Jul 01 2022
Journal Name
Iraqi Journal Of Science
Determining the Level of Radioactivity and Hazard Index of the Soil of Babylon Batteries Second Plant in Waziriya
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Thisre search was used in the short term method has been employed to determine the radioactive contamination from elements of natural and artificial radioactive.So, the natural gamma ray spectrum analysis technique using NaI(Ti) have been used to measure the The specific activity of the radioactoctive isotopes as following, U-238,Th-232 series of (Pb214,Pb212) respectively as wall as K-40 and industrial radioactive isotope Cs-137 was determined in the studied samples ,which are consisted of 30 samples from different locations and depth(10-50)cmthe samples of the soil batteries plant in Waziriya in Baghdad, as wall as Hazard index its found it within the permissible internationally.

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Publication Date
Mon Mar 08 2021
Journal Name
Baghdad Science Journal
Impact germination in the content of the chemical components of Homs and sensory qualities of Biskt plant it,
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This study was conducted to identify the impact of germination in the ratio Almaah of Chemical Constituents of Homs and in the organoleptic properties of the Biskt plant it and compare the results with the treatment control (seeds Almnepth) Adhrt results for a significant increase in the percentage of crude protein with the progress of the process of germination, reaching 24.5% in percentage of crude protein with the progress of the germination process Krbu hydrate college during the germination period, reaching 59.2% in the fourth day

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Publication Date
Sun Jul 29 2018
Journal Name
Iraqi Journal Of Science
Investigation of the presence of some virulence factors of the Streptococcus pneumoniae isolates among patients in Basra Governora
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Extensive studies have been conducted on the microbial properties of Streptococcus pneumoniae  all over the world ,but there are few studies in Iraq on the most important factors of virulence possessed by S.pneumoniae isolates found in Iraq , 195 of sputum specimens were collected from patients with pneumonia acquired from the community who were clinically diagnosed by specialized doctors depending on symptoms and  Radiography of Chest . Eighteen isolates of  S.pneumoniae were  diagnosed  by  special traditional methods that used in the phenotypic identification . All isolates 18 (100%) have been  given  positive results for  the optochin test , bile solubility test

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