Background: Lymphoblastic lymphomas (LBL) are neoplasms of precursor T cells and B cells, or lymphoblasts. The term lymphoblastic lymphoma has been used to describe predominantly lymph node– based disease; however, clinical distinction between LBL and acute lymphoblastic leukemia (ALL) has been arbitrary and has varied among different studies and institutions
Objectives: To determine the frequency of LBL among all Non-Hodgkin’s lymphoma (NHL) patients in children and to study the clinical and pathological features of LBL and assess the treatment outcome.
Methods: A retrospective study included 28 children with newly diagnosed LBL (based on morphology) below the age of 14 years over 8 years period from January 1st, 2000 to December 31st, 2007 All the patients except one were treated by modified Medical Research Council UK National Randomized Trial For Children and young Adult with Acute Lymphoblastic Leukemia (MRC UKALL) regimen, one patient was misdiagnosed as B-cell NHL and treated with United Kingdom Children’s Cancer Study Group (UKCCSG) Non-Hodgkin’s Lymphoma protocol.
Results: LBL forms 28/376 (7.1%) among NHL diagnosed in Children Welfare Teaching Hospital (CWTH) in the same period. The median age was 8.95 years (range 2 to 13.25 years) with male to female ratio of 3.7:1. Lymphadenopathy was present in 22 (78 .6%) of patients. The median duration of onset of symptoms was 7.25 months (range 1 week to 18 months). In response to treatment, 20 (71.4%) patients achieved complete remission (CR), 1 (3.6%) died during induction and 7 (25%) patients were non-responder (4 died and 3 abandoned). Of the 20 patients who achieved complete remission (CR); thirteen (46.4%) remained in continuous complete remission with a median follow up of 32.3 months, 3 (10.7%) patients died while in
CR in an average of 16.6 weeks, 2 (7.1%) patients abandoned treatment and 2 (7.1%) patients relapsed.
Conclusion: The study showed a low frequency of LBL in comparison with other studies which might be due to inadequate diagnostic facilities which differentiate LBL from other types of NHL, low survival rate might be due to advanced stages at presentation in addition to abandonment of treatment in some patients
Background: Transient tachypnea (TTN) is a common disorder of the newborn. It is characterized by the
early onset of tachypnea sometimes with retractions or expiratory grunting and occasionally cyanosis that is
relieved by minimal oxygen supplementation (<40%).
Objectives: To identify the risk factors and describe the clinical characteristics, treatment and outcome of
infants with TTN.
Patients and methods: This study was carried out on 100 newborn babies with birth weight of 2500 to 4000 &nbs
Fac Med Baghdad 2014; Vol.56, No.2 Received: April. 2014 Accepted May. 2014
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Background: Gastroenteritis is a common illness in pediatric age group; the causes could be bacterial, fungal or viral infection. Rotavirus is the most common cause of infectious diarrhea in children. Children between 3 months to 2 years old have the most severe symptoms. Rotavirus is extremely easy to catch and is transmitted mainly by the oral- fecal route. For diagnosis; the specimen of choice is the stool which has been collected during the first 3 to 5 days of illness. If collected 8 or more days after onset of symptoms the specimen will rarely contain the virus.
Objective: The objective of
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Background: Respiratory distress remains a major problem post adaptation and one of the most common reasons for admission of neonates to Intensive Care.
Objectives: To study the causes and short term outcomes of respiratory distress in full term neonates and its correlation to mode of delivery.
Patients and Methods: A cross sectional study was carried out on 100 full termoutborn neonates with respiratory distress admitted to Neonatal care unit of Children Welfare Teaching Hospital, Medical City, Baghdad from 1st of April to 31st of August 2011.
Results: Hundred full term neonateswerestudied, 66% were boys and 81% born by cesarean section (elective cesarean sectionin 62%). In both sexes, Transient TachypneaofNewbornan
Backgroun1d: Polycythemia is defined as a central Hematocrit of at least 65%. Its` incidence is increased in babies who have intrauterine growth restriction (IUGR), are small for gestational age (SGA), and are born post term. Many infants with polycythemia are asymptomatic. However, it may be associated with feeding problems and lethargy.
Objectives: This work aimed to study the polycythemic neonates admitted to neonatal care unit in children welfare teaching hospital, medical city complex, Baghdad, including demographic features, risk factors, management and early outcome.
Patients and Methods: A descriptive study was carried out over
... Show MoreBackground: Guillain-Barre syndrome (GBS) is the most common cause of acute motor paralysis in children where most of electrophysiological findings reveal demyelinating neuropathy. However, an axonal form of Guillain-Barre syndrome had been reported too.
Objectives: Assess the role of neurophysiological study (EMG and NCS) in the diagnosis of Guillain-Barre syndrome subtypes in children and estimate the frequency of subtypes whether demyelinating or axonal form of Guillain-Barre syndrome.
Subjects and methods: Two study groups of either sex was involved, thirty (30) Guillain-Barre patients with different ages and thirty(30) normal healthy subjects matched for age and gender served as control group. Each subject submitted to sensory
Background: The prevalence of congenital anomalies at birth is underestimated in developing countries due to the unavailability of perinatal diagnostic tests or accurate medical records. The prevalence of congenital defects may help to establish a baseline, track changes over time, and uncover etiological clues.
Objectives: This study aims to evaluate the prevalence and types of major congenital anomalies in one of the main referral tertiary centers in Baghdad, highlighting the parent and neonatal characteristics and assessing the mortality rate in this group of patients.
Patients and Methods: A prospective cohort study was conducted in Baghdad Teaching Hospital dur
... Show MoreBackground: The optimal timing of surgery for Wilms' tumor has been debated for many years. It appears dubious whether surgical ease or per operative complications consistently improved after preoperative chemotherapy.
Materials and Methods: This is a cross section study ,the sample collected from January 2009 to November 2012 .Thirty four patients were selected after informed consent . Patients aged between 10 months and 5 years who were newly diagnosed with Wilms' tumors. including (17) patients with unilateral wilms tumors received immediate nephrectomy without preoperative chemotherapy according to the National Wilms' Tumor Study Group protocol and (1
... Show MoreBackground: Subjects with Autism Spectrum Disorder (ASD) have a higher prevalence of seizures than the general population, according to a significant body of research. Also, seizure-free patients with ASD have been found to have a higher prevalence of epileptiform discharge abnormalities compared to healthy controls across investigations. Changes in the electroencephalogram (EEG) can manifest as sharp waves or spikes, sharp and slow waves, generally distributed or general area, or focused, and can manifest in various brain regions. There is a necessity to search for a distinctive EEG characteristic in ASD patients.
Objectives: This study used electroencephalography to investigate the relationshi
... Show MoreBackground: Congenital adrenal hyperplasia is a family of autosomal recessive disorders of cortisol biosynthesis. Depending on the enzymatic step that is deficient, there may be signs, symptoms, and laboratory findings of mineralocorticoid deficiency or excess; incomplete virilization or premature puberty in affected males; and virilization or sexual infantilism in affected females. The most frequent is 21-hydroxylase enzyme deficiency, accounting for more than 90% of cases.
Objectives: to review cases of congenital adrenal hyperplasia registered in children welfare teaching hospital- medical city- Baghdad.
Patients and method: This study included all patients who were presented and registered in the e