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iqjmc-502
Immunohistochemical Expression of Estrogen and Progesterone Receptors in Human colorectal Carcinoma (Clinicopathological study)
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Background: Colorectal adenocarcinoma is the most common type of gastrointestinal cancer, with about 150,000 cases each year in the United States and about 56,730 deaths from colorectal cancer risk. In Iraq and according to the Iraqi cancer registry (ICR) reports, the incidence of colorectal carcinoma was 4.55% of whole body malignancy, & it is the seventh cause of death from cancer (ICR 2005). In males, it’s the 7th common cancer while in females it’s the 4th most common cancer. The estrogen and progesterone receptors belong to a super- family of nuclear hormone receptors. These receptor proteins function as transcription factors when they are bound to their respective ligands, these receptors shares a common structural and functional organization

Objectives: to evaluate the immunohistochemical expression of estrogen (ER) and progesterone (PR) in colorectal adenocarcinoma and to correlate this expression with different clinical and pathological parameters.

Material and method: Twenty five cases of colorectal adenocarcinoma diagnosed in private laboratories in Baghdad/Iraq from November 2011 to march 2013, were respectively evaluated in term of age, gender, pathological diagnosis, including the tumor site, size, lymph nodes status, grade and stage of tumor. Using infiltrative ductal carcinoma of the breast as control for both estrogen and progesterone receptors expression were investigated immunohistochemically, nuclear and cytoplasmic staining of tumor cells were accepted positive.

Results: Fourteen (56%) of the cases were male, 11 (44%) case were female, with age distribution ranging from (24-84) years, with a mean age of 56.5 year. Tumor size ranges between 2.5-10 cm, mean of 6.25 cm. Seven cases (28%) cases were from the caecum, 5(20%) from each rectum, sigmoid and left colon respectively and 3(12%) cases were from more than one segment of the colon. Histologically the tumor grade ranges from moderately differentiated in 23(92%) cases and poorly differentiated in 2(8%) cases. Regarding pathological staging (TNM system), 5(20%) cases were stage T2, 17 (68%) cases were stage T3 and 3(12%) cases were T4, lymph node involvement found in 10(40%)  cases and distant metastasis were found in 2 (12%) cases. Estrogen receptors expression was positive in 2(8%) cases, while progesterone receptor was positive in 5(20%) cases; both ER positive cases were PR positive. Both ER positive cases were female; one of the PR positive cases was male. All of the ER and PR positive cases were moderately differentiated, one case of ER positive tumor showed nodal involvement while three cases of PR positive showed nodal involvement.      

Conclusion: - Estrogen and progesterone receptors in colorectal adenocarcinoma had same activity. The level of ER and PR expression in tumor tissue could not predict malignant biological behavior of the colorectal adenocarcinoma. No significant statistical correlation was observed between ER, PR expression and any of the studied clincopathological parameters.

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Publication Date
Thu Aug 30 2018
Journal Name
Iraqi Journal Of Science
Sedimentology and Basin Development of the Middle Miocene Succession in the Zurbatiya Area, Eastern Iraq
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The present study is focused upon the sedimentology and basin development of the Jeribe and Fatha Formations by using the field observations and microfacies analysis. The area of study situated in the Zurbatiyah area to the south of the Shur sharin valley about 21 km northeast of Badrah city to the southeast of Baghdad. This area lies within the Zagros foreland basin, and located between the Zagros mountains at the northeastern and the Arabian shield at the southeastern.

     The studied succession which including the Jeribe and Fatha Formations were deposited within four associated facies for the Jeribe Formation and three for the Fatha Formation, as shown below: -

Jeribe Formation

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Publication Date
Sun Jun 05 2016
Journal Name
Baghdad Science Journal
Flame Atomic Emission and Colorimetric Methods for the Determination of Cephalexin Monohydrate in Pharmaceutical Preparations
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We propose two simple, rapid, and convenient spectrophotometric methods which are described for the determination of cephalexin in bulk and its pharmaceutical preparations. They are based on the measurement of the flame atomic emission of potassium ion (in the first method) and colorimetric determination of the green colored solution at 610 nm formed after the reaction of cephalexin with potassium permanganate as an oxidant agent (in the second method) in basic medium. The working conditions of the methods are investigated and optimized. Beer's law plot shows a good correlation in the concentration range of 5-40?g ml-1. The detection limits are 2.573,2.814 ?g ml-1 for the flame emission photometric method and 1.844,2.016 ?g ml-1 for colo

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Publication Date
Wed Mar 10 2021
Journal Name
Baghdad Science Journal
Particle size effect on XRF measurements of Copper and Zinc particles suspended in hydrocarbon materials
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Copper and Zinc powders with different particle sizes were subjected to sieving of range (20-100?m) and He-Ne laser system to determine the particle size . 1wt% from each powders was blended carefully with 99wt% from Iraqi oil . Microscopic examination were carried for all samples to reveal the particle size distribution . XRF intensity measurements were conducted for all suspended samples , and the relation between XRF intensity and the particle size was found .

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Publication Date
Tue Mar 14 2023
Journal Name
Iraqi Journal Of Science
On the Dynamics of Prey-Predator Model Involving Treatment and Infections Disease in Prey Population
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In this paper, a mathematical model consisting of the prey- predator model with treatment and disease infection in prey population is proposed and analyzed. The existence, uniqueness and boundedness of the solution are discussed. The stability analyses of all possible equilibrium points are studied. Numerical simulation is carried out to investigate the global dynamical behavior of the system.

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Publication Date
Sat Dec 11 2021
Journal Name
Engineering, Technology & Applied Science Research
Evaluation of Rutting in Conventional and Rubberized Asphalt Mixes Using Numerical Modeling Under Repeated Loads
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This research aimed to predict the permanent deformation (rutting) in conventional and rubberized asphalt mixes under repeated load conditions using the Finite Element Method (FEM). A three-dimensional (3D) model was developed to simulate the Wheel Track Testing (WTT) loading. The study was conducted using the Abaqus/Standard finite element software. The pavement slab was simulated using a nonlinear creep (time-hardening) model at 40°C. The responses of the viscoplastic model under the influence of the trapezoidal amplitude of moving wheel loadings were determined for different speeds and numbers of cycles. The results indicated that a wheel speed increase from 0.5Km/h to 1.0Km/h decreased the rut depth by about 22% and 24% in conv

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Publication Date
Wed Jun 08 2022
Journal Name
Applied Sciences
Effect of Adjuvant, Concentration and Water Type on the Droplet Size Characteristics in Agricultural Nozzles
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One of the goals of adding adjuvants to agricultural spray solutions is to enhance the droplet size characteristics of this spray. Droplet size, in turn, has an influence in the deposited spray quality, in addition to the drift and losses of spray to off-target places. The aim of this research was to evaluate the effect of adding adjuvants to two types of water from different sources on the droplet size characteristics. Two types of adjuvants were employed in the tests: the active substance content of the first adjuvant was a 50% aqueous solution of sodium salt of alkylbenzenesulfonic acid—10% (HY), whereas the second was from rapeseed oil (natural origin)—85% (OL). Both adjuvants were tested in two concentrations: the first was

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Publication Date
Fri Sep 27 2019
Journal Name
Journal Of Baghdad College Of Dentistry
Antimicrobial efficacy of silver, zinc oxide, and titanium dioxide nanoparticles incorporated in orthodontic bonding agent
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Background: One of the most important complications of fixed orthodontic treatment is formation of white spots, which are initial carious lesions. Addition of antimicrobial agents into orthodontic adhesive material might be wise solution for prevention of white spots formation. The aim of this study was to evaluate the antibacterial properties of orthodontic adhesive primer against S. Mutans after adding the three different types of nanoparticles (Ag, ZnO, or TiO2). Materials and methods: Discs were prepared using empty insulin syringe approximately 2 mm×2 mm rounded in shape specimens (40 discs) were divided into four groups (ten discs for each group): The first group was the control (made from primer only), the second group (10 dis

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Publication Date
Wed May 10 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Density and Viscosity of Amino Acid Serine in Aqueous Dimethyl Sulfoxide Solution at Different Temperatures
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Densities
 and viscosity
 of serine in 20, 40, and 60% (w/w) dimethyl sulfoxide (DMSO)-water mixtures were measured at 298.15, 303.15 and 308.15k. From these experimental data, apparent molal volume v  , limiting apparent molal volume v  o , the slop v S , transfer volume  v  o(tr), Jones-Dole coefficients A and B were calculated. The results are
v  odiscussed the solute-solvent and solute-solute interaction, and showed that serine behaves as structure-breaker in aqueous DMSO solvent

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Publication Date
Thu Jan 31 2019
Journal Name
Journal Of Engineering
Heat Transfer Analysis of Conventional Round Tube and Microchannel Condensers in Automotive Air Conditioning System
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In this paper, an experimental analysis of conventional air-cooled and microchannel condensers in automotive vapor compression refrigeration cycle concerning heat transfer coefficient and energy using R134a as a refrigerant was presented. The performance of two condensers and cycles tested regarding ambient temperature which it was varied from 40oC to 65oC, while the indoor temperature and load have been set to be 23oC and 2200 W respectively. Results showed that the microchannel condenser has 224 % and 77 % higher refrigerant side and air side heat transfer coefficient respectively than the coefficients of the conventional condenser. Thus, the COP, in case of using the microchannel

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Publication Date
Wed Feb 22 2023
Journal Name
Iraqi Journal Of Science
Facies, Depositional Environment and Cyclicity of the Fatha Formation in East Baghdad Oil Field, Iraq.
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This study deals with establishing the depositional environment of the Fatha Formation through facies analysis. It also deals with dividing the formation into units based on the rhythmic nature. Data from selected shallow wells near Hit area and deep wells at East Baghdad Oil field are used. Five major lithofacies are recognized in this study, namely, greenish grey marl, limestone, gypsum (and/or anhydrite), halite and reddish brown mudstone (with occasional sandstone).The limestone lithofacies is divided into three microfacies: Gastropods bioclastic wackestone microfacies, Gastropods peloidal bioclastic packstone, and Foraminiferal packstone microfacies.The lithofacies of the Fatha are nested in a rhythmic pattern or what is known as sh

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