Background: Polycystic ovary syndrome (PCOS) is one of the common female endocrine disorders of uncertain etiology, which causes menstrual disorders as well as infertility. Interleukin–33(IL-33) is considered as a strong risk marker of inflammation and may have possible role in pathogenesis of PCOS.
Objectives: The present study is designed to investigate the possible role of IL-33 in pathogenesis of PCOS and its relation with glycated hemoglobin (HbA1C),insulin resistance(IR) and oxidative stress in prediabetic PCOS patients.
Subjects and Methods: The study involved 30 healthy women as control group and sixty six infertile Iraqi women with PCOS which were divided into two groups according to glycated heamoglobin(HbA1c) value and homeostasis model assessment for insulin resistance (HOMA-IR). The first group (G1) consist of 30 women with HbA1c ≤ 6.5% and HOMA –IR<3.8 as PCOS without diabetes and without insulin resistance. The second group(G2) consist of 36 patients with HbA1c ≥ 6.5 % and HOMA-IR ≥ 3.8 as PCOS with pre diabetes type 2 and insulin resistance. Ten milliliters of blood were collected from all subjects by vein puncture during 2nd – 4th day of the menstrual cycle. Two ml of blood were collected in EDTA tube for HbA1c analysis. The serum which obtained from the remained blood were used for determination of (insulin, fasting blood glucose(FBG), Malondialdehyde(MDA) , Total antioxidant capacity(TAC) , uric acid, glutathione(GSH), albumin, and IL-33) .
Results: Results revealed a significant elevation in HbA1c, insulin, HOMA-IR, MDA, TAC, uric acid and IL-33 in the patients group when compared with healthy women. On the other hand, a significant decreased in GSH and albumin were found in patients group when compared with control group. Also there are significant differences in the results between patients in group 1 and group 2. A significant positive correlation between IL-33 and HbA1c levels was noticed in G1 and G2 .A significant positive correlation between IL-33 and HOMA-IR was noticed in group 1 while a negative significant correlation was found in group 2. No correlation founded between IL-33 levels and TAC concentration in group 1, but a positive correlation noticed with group 2. A significant negative correlation was observed between IL-33 and MDA/TAS ratio in G1, while a significant positive correlation in G2 was found.
Conclusion: high levels of IL-33 in patient groups may be considered as a novel cytokine involved in the pathogenesis of PCOS. Also the elevation in oxidative stress in PCOS patients could be a reason for disturbed follicular development and ultimately infertility.
Characteristic of money laundering phenomenon is a compound and complex nature like the style of regular crimes . These operations are planned and excuted with those who have high quality experiences to hide the evidences of their deeds so They ask the help of financials ,economicals and legists to plan for money laundering. Banks are important and suitable places for illegal circulation of money because of the different types of accounts , rapidity and overlap which emphasis of its main duty to dislocate illegal money which comes from illegal sources without adding legal characteristic to it . Here we should explain the important role of banks in striving the phenomenon –Bank should try to show and analyze inward proced
... Show More The present study describes a protocol for rapid in vitro micropropagation of Albizia lebbeck during the period of October 2007 to October 2009 through nodal segments containing axillary buds. The buds induced to produce a large number of multiple shoots by culturing on MS medium supplemented with different concentrations of BA (benzyladenine) and NAA (α-naphthalene acetic acid). The maximum number of shoots per explants was obtained on MS medium supplemented with 1.0 mg/L BA and 0.1 mg/L NAA was (4.8) after 4 weeks of culture. Excised shoots were rooted on half strength MS medium fortified with 0.5 mg/L either IBA (indolbutyric acid) or NAA alone. The complete plantlets thus obtained were successfully transferred to soil.
Background: - Carcinoma of the lung has became the most common type of cancer since 1985 & the most common cause of cancer death in both males & females.
Aim of study: - To assess the diagnostic accuracy of bronchial wash cytology & application of immunocytochemical methods, using two tumor markers (low molecular weight cytokeratin & epithelial membrane antigen) for more accurate & precise diagnosis of lung tumors.
Patients, materials and methods: - Fifty fifes suspected lung cancer cases according to their clinicoradiological examinations were included in this study.
Bronchial wash cytology was performed for all the 55 patients. Smears were stained by conventional cytological stain i
The corrosion behavior of Zn in 0.1 M HCl solution containing various concentration of Ampicillin range (2 x 10-4 – 1x10-3) M was investigated. The corrosion rates were measured by using weight loss measurement and polarization curve, The results of polarization method obtained showed that the rate of corrosion of zinc increased with increasing the temperature from 293K to 323K and the values of inhibition efficiency of ampicillin increased with increasing the temperature and AMP concentrations, the results showed that AMP caused to protection efficiency reached to 88.8% when (1x10-3) M AMP concentration was used in 323K. The coverage (θ) of metal surface by AMP could be obtained from the rate of corrosion in the presence and absence
... Show MoreThe aim of this research is to analyze Chaucer’s use of idealism in the “General Prologue” to The Canterbury Tales. Idealism is defined as a belief that ideals are the only true reality. Therefore, it stresses the mental or spiritual over the material objects.Idealism is widely used during the Middle Ages, especially by Geoffrey Chaucer, who is England’s most famous poet. The Canterbury Tales is his masterpiece. This Research analyzes ideals in the “General Prologue” toThe Canterbury Tales.
The conclusion of the present research shows that Chaucer uses idealism to criticize the follies and weaknesses of his age.Besides, he finds that adherence to ideal values is a means to cultivate morality leading to perfectio
... Show MoreThe budget in general is a plan of action prepared by the government and works to submit it to the legislative authority for the purpose of approval, and translates its economic and social policy into annual digital targets. In order to know the effectiveness of the public budget, it must be linked to other financial planning tools such as foreign exchange policy and credit policy and measured by the economic and social results and not only financial results.
And to avoid the shortcomings that accompanied the budget because of the use of the traditional method of balancing items and finding remedies to get out of the financial crises experienced by countries in general and Iraq in particular in the
... Show MoreIn this research, attempt to overcome and quantities the problem of the large number of frequency of dust storms and the areas that generated and then identifying these areas in order to be held by the agricultural areas, as has been the adoption of many of the techniques and methods of processing image in remote sensing and geographic information systems and linking them together to identify those areas in Iraq or the neighbors, especially the northern and north-west wind of the fact that Iraq is in the northern and north - western most days of the year. Research has included the use of images from the satellite (MODIS) with quality (Aqua) and (Terra) with the assembly of the amount of dust, these storms, it was determining the values o
... Show MoreThe objective of this study was to assess the nutritional status of childs of nurseries in Baghdad city so that an early detection of malnutrition cases could be carried out. The results revealed that the daily consumption of food calories, protein, fat and carbohydrate were 1180.5 calories, 27.2gm, 38gm and 180gm, respectively, which were less than the RDA values and the percentages of these nutrients supplied by the food intake were 90.8, 83.7, 87.3 and 90.3%, respectively. It was also demonstrated that the highest percentages of stunting, underweight and wasting, which amounted to 32, 22.7 and 1.5%, respectively, were among those childs who obtained inadequate calories, while the percentages of the forementioned malnutrition cases amon
... Show MoreThis research deals with a unique and innovative topic, that is the study of complaint in the Quranic text. Despite its importance, it has never been studied before, because most of the complaint 's meanings in the Quranic text is: the in explicit complaint. The mentioned complaint's expressions in different contexts overlap with other purposes, in particular call method and its peripherals like mourn , ask for help , exclamation and others.
Moreover, expressions that reveal complaint are related to the complainant's emotional and psychological status, and the complaint's context.
This research deals with the topic into two sections: The first deals with the important expression of complaint such as: iff, ouah, mooing, crying. The
Anti-Neutrophil Cytoplasmic Antibodies (ANCA) are a heterogeneous group of autoantibodies with a broad spectrum of clinically associated diseases. The diagnostic value is established for Proteinase 3 (PR3)-ANCA as well as Myeloperoxidase (MPO)-ANCA. To estimate the frequency of anti-neutrophile cytoplasmic antibodies (ANCA) in sera from a group of Iraqi patients with some autoimmune diseases compared with a healthy control group. Serum samples were collected from one hundred patient, 47 males and 53 females; with age range of 16-70 years; 20 specimens from patients with systemic lupus erythematosus (SLE), 30 from patients with ulcerative colitis (UC), and 50 from patients with rheumatoid arthritis (RA). A group of 40 apparently healthy b
... Show More