Fibroblast growth factors-23 (FGF-23) are a class of cell signaling proteins produced by macrophages. They have a range of roles, but they play a particularly important role in the development of animal cells, where they are essential for appropriate growth. Phosphate, which is found in the body as both organic and mineral phosphate, plays crucial roles in cell structure, communication, and metabolism. Most phosphate in the body resides in bone, teeth, and inside cells, with less than 1% circulating in serum. The aim of the study is to evaluate the levels of the Fibroblast Growth Factors-23 and phosphate and receiver operating characteristic (ROC) in acromegaly patients against healthy control. A case control study Fibroblast Growth Fact

The expression of the Proprotein Convertase Subtilisin/Kexin Type 9 gene (PCSK9) is inextricably related to lipid levels and a risk of atherosclerotic coronary artery disease (ASCAD). The present study aims to measure the quantity of PCSK9 gene expression and the effect of methylation on its expression level taking part in the pathogenesis of acute coronary artery disorder.

A current study included 150 subjects from the Iraqi population, 100 ASCAD patients and 50 healthy controls. The concentration of PCSK9 in each serum sample was determined by the ELISA technique, the expression levels of the PCSK9 gene in whole blood were estimated by RT-qPCR – Quantitative Reverse Transcription PCR method, and DNA

Background: Fibromyalgia syndrome (FMS) is a very common cause of multiple regional musculoskeletal (MSK) pain and disability; it is characterized by chronic widespread for at least
three months and tender points identified by the American Collage of Rheumatology (ACR).The cause of FMS is currently unknown. However, several hypotheses have been developed including genetic predisposition. This study aims to evaluate the contribution of serum lipid profile to the pathophysiology of FMS.
Patients & Methods: The study has included 160 patients with FMS with age range (18-72) years and 60 control individuals who were age and sex matching with FMS patients: 29 patients with chronic musculoskeletal compla

Background: Fibromyalgia syndrome (FMS) is characterized by widespread musculoskeletal pain with associated symptoms including stiffness, fatigue, sleep disturbance and functional impairment. FMS is depicted by chronic pain for at least three months and tender points identified by the American Collage of Rheumatology (ACR). Although several hypotheses have been developed; the cause of FMS is currently unknown.
This study aims to evaluate the contribution of serum apolipoprotein (a) [Apo (a)], leptin, and serum lipid profile to the pathophysiology of FMS.
Subjects & Methods: The study has included 160 patients with FMS with age range (18-72) years and 60 control individuals who were age and sex matc

Background: Toxic-shock syndrome (TSS) is an acute onset; multiorgan disease caused mainly by Toxic-shock syndrome toxin-1 (TSST-1) producing Staphylococcus aureus strains.Testing for TSST-1 or anti-TSST-1 antibodies in the clinical setting may help to predict and prevent the appearance of TSS caused by nosocomial S. aureus infection.
Objectives: Detection of TSST-1 in the sera of children patients arranged to undergo surgical operations, and its relevance with certain demographic factors.
Patients and methods: This cross-sectional study was conducted in the Baquba General Teaching Hospital- Diyala province for the period from August 2015 to April 2016. Eighty eight patients from those undergoing surgical operations were enrolled.

This study designed to examine association between-174G/C polymorphism of interleukin-6 gene and phosphate, calcium, vitamin D₃, and parathyroid hormone levels in Iraqi patient with chronic kidney disease on maintenance hemodialysis. Seventy chronic renal failure patients (patients group) and 20 healthy subjects (control group) were genotyped for interleukin-6 polymorphism and genotyping was performed by conventional polymerase chain reaction-restriction fragment length polymorphism. No significant differences in phosphate levels were observed in patients and control with different interleukin-6 genotypes. Control had non-significant differences in calcium levels, while patients with GG and CG genotypes displayed significant e

Background: Osteoarthritis OA is the most common joint disorder in the world. Injection of high molecular weight hyaluronic acid intra-articular with steroid is a one of the used therapeutic option for patients with (OA)knee.

Objectives: Objective of this study was the evaluation the efficacy, safety, pluse duration of action of viscosupplementation of the  HMWHA( high molecular weight hyluranic acid ).

Type of the study: Cross-sectional study.

Methods: From 81 patients with sever knee pain due to OA (grades 3–4) were recruited from Al-Yarmouk teaching hospital  & a private clinic during the period from January 2014 till July 2016.

Background: Fibromyalgia syndrome is a common rheumatological syndrome with multiple systemic manifestations & associated with many diseases. The aim of the study is to assess the
possible association between fibromyalgia syndrome (FMS) & chronic obstructive pulmonary disease (COPD), and to correlate this association with patient's age, age group, sex, marital status, duration of the disease, & its severity.
Patients and Methods: Fifty patients with COPD & 50 healthy controls were included in this study. Full history was taken & complete physical examination was done for all patients in both groups. Disease characteristics [age, age group, sex, marital status, duration of the disease, &a

Back ground: The epidemic of obesity is a major health problem in the developed world with a great influence on morbidity and mortality.
The aim of study: to evaluate serum ghrelin levels achieved through LSG and on insulin resistance and the serial changes of insulin concentration in obese patients following gastric sleeve.
Patients and methods: twenty four patients underwent LSG with 25 controls were selected. Body mass index (BMI), waist circumference (WC), lipid profile, fasting blood sugar (FBS), glycated hemoglobin (HbA1c), fasting insulin, QUICKI and ghrelin hormone concentrations were measured for controls and patients prior LSG, then one month and three months post-surgery.
Results: A significant decline was noticed in

Background: Fibromyalgia syndrome (FMS) is a chronic musculoskeletal disorder characterized by wide spread body pain, chronic fatigue,