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Assessment of endothelial dysfunction by flow mediated dilatation in patients with Coronary Artery Disease
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Background: Endothelial dysfunction is thought to be a key event in the development of atherosclerosis. It is a systemic process that simultaneously affects different vascular territories including coronary arteries. It is recommended that noninvasive approaches assessing endothelial function in peripheral vessels like flow mediated dilatation are indirectly representative of coronary vascular function.
Objectives: This study is aimed to assess endothelial dysfunction by using flow mediated dilatation in patients with coronary artery disease
Patients and methods: 82 patients of either sex with an age range of 40-65years are involved in this study. Each patient was subjected to two tests; first test was the flow mediated dilatation percentage (FMD%) measurement to assess endothelial functional integrity and second one was coronary computerized tomography angiography for measuring the percentage of coronary artery stenosis.
Results: the results of this study revealed that FMD% is inversely correlated with the percentage of coronary artery stenosis (p value <0.01). FMD% in patients having a single coronary vessel atheromatous stenosis (9.9±3.5) % was significantly lower than that of control subjects (15.3±7) %, p<0.0001.
Conclusion: this study concludes that FMD% of brachial artery could be used as a marker for systemic endothelial functional integrity including that of coronary arteries.

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Publication Date
Mon Jan 02 2012
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Effect of fibromyalgia syndrome (FMS) on disease activity (DAS28) score in patients with rheumatoid athritis(RA)
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Background: rheumatoid arthritis (RA) is a systematic autoinmume disease with prevalence of 1% world wild, it is characterized by chronic inflammation of synovial joints, which commonly leads to progressive joints destruction and consequent disability with reduction in quality of life of life.

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Publication Date
Sun Jan 03 2016
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Complication Following percutaneous coronary intervention via the femoral artery Experience in lraqi center for the Heart Disease and lbn Al-Bitar Hospital for cardiac surgery.
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Background: Vascular complications have been recognized as an important factor in morbidity after diagnostic and percutaneous coronary interventions.
Objectives: This study sought to evaluate vascular complications after diagnostic coronary angiography and percutaneous coronary intervention (PCI) from the common femoral artery.
Patients and methods: This prospective cohort study was carried out over a year period, from February 2008 till January 2009, at the Iraqi Center for the Heart Disease and Ibn Al-Bitar Hospital for Cardiac Surgery. A total number of 2400 patients underwent 3600 procedures, diagnostic coronary angiography (2196) and PCI(1404) via their common femoral arteries were included in this study.
Result: A total 40

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Publication Date
Tue Feb 01 2022
Journal Name
Baghdad Science Journal
Flow Injection Analysis with Turbidity Detection for the Quantitative Determination of Mebeverine Hydrochloride in Pharmaceutical Formulations
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The main objective of this paper is to develop and validate flow injection method, a precise, accurate, simple, economic, low cost and specific turbidimetric method for the quantitative determination of mebeverine hydrochloride (MbH) in pharmaceutical preparations.  A homemade NAG Dual & Solo (0-180º) analyser which contains two identical detections units (cell 1 and 2) was applied for turbidity measurements. The developed method was optimized for different chemical and physical parameters such as perception reagent concentrations, aqueous salts solutions, flow rate, the intensity of the sources light, sample volume, mixing coil and purge time. The correlation coefficients (r) of the developed method were 0.9980 and 0.9986 for cell

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Publication Date
Tue Apr 01 2014
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Comparative Study of Allopurinol and Uralyt-4 in patients with Hyperuricemia in Diyala Governorate.
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Background: Hyperuricemia represents a major public health problem; approximately most population has hyperuricemia, serum uric acid ≥6.5 mg/dL in women and ≥7.0 mg/dL in men.
Allopurinol has been approved for the treatment of hyperuricemia patients. Epidemiological and experimental studies suggest a linkage between hyperuricemia and type of treatment.
Objective: To assess the effect of allopurinol and uralyt- 4 and mixture of two drugs (allopurinol and uralyt-4) in hyperuricemia patients
Methods: A total of 60 serum patients with history of hyperuricemia, obtained from Baladrus Hospital in Diyala governorate, were included in this study. In addition, ten normal uric acid level persons used as contro

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Publication Date
Wed Dec 01 2021
Journal Name
Baghdad Science Journal
Association of Circulating MicroRNA-142-3p with Graves Disease
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This study aims to investigate the possible role of circulating microRNA-142-3p (miR-142-3p) in the
development of graves disease (GD) and its association with the antibody directed against thyroid
stimulating hormone receptor (TSHR-Ab) production in patients with GD. Forty patients with positive
TSHR-Ab enrolled in this study were divided ,based on treatment, into (22 untreated (newly diagnosed) and
18 treated patients) and based on family history (30 with positive family history and 10 with negative family
history). In addition to forty healthy subjects with sex and age matching as a control group. The expression
level of circulating miR-142-3p was determined by two steps reverse transcription polymerase c

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Publication Date
Sun Jan 04 2015
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Laparoscopic splenectomy using bipolar vessel sealing system
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Background: Newly developed vessels sealing device built upon bipolar diathermy technology had a great
impact on facilitating advances laparoscopic surgery. Laparoscopic splenectomy is well established procedure
but in this study the procedure is totally based on bipolar vessel sealing system in devascularization of the
spleen.
Objective: To evaluate the safety of laparoscopic splenectomy with vessels sealing device and its
outcome.
Patient and method: Prospective study conducted in Baghdad Teaching Hospital and Dijlah private hospital
from October 2009 to October 2013. Thirty patients with idiopathic thrombocytopenic purpura(ITP) were
included and had laparoscopic splenectomy . The adapted procedure was stapleles

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Publication Date
Sun Jan 03 2016
Journal Name
Journal Of The Faculty Of Medicine Baghdad
The Clinico-epidemiologic Characteristics of Iraqi Patients with Neuroendocrine Tumors and Their Response to Long Acting Octreotide
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Background: The lack of studies regarding the neuroendocrine tumors (NET) is related to the rarity of these tumors .Long acting Octreotide is an established treatment for NETs by both providing symptomatic relief & inhibiting tumor growth. However, studies regarding incidence of NETs & their response to long acting Octreotide are still insufficient.
Objectives: To study the clinico-pathologic characteristics of Iraqi patients with NET & their response to long acting Octreotide.
Patients & methods: This is a cross-sectional observational study that was conducted in Oncology teaching hospital using patients’ follow-up records. Data recruitment included all NET patients diagnosed after October 2013.
Results: Durin

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Publication Date
Sat Aug 25 2018
Journal Name
Oriental Journal Of Chemistry
Estimation of preptin in serum of Thyroid Dysfunction Patients and its Relationship with other Parameters
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The research includes a clinical study of Preptin with other parameters. The normal value of preptin in hypothyroidism (2638.4±280.0) in female while (2960.4±256.6) in male, in hyperthyroidism (589.0±90.1) in male, while in female (993.2±103.9), diabetes (2465.6±282.4) in female, in male (2085.5±282.8), in diabetes & hypothyroidism (3314.3±177.3) in male,(3179.4±265.7) in female, but control group in female (427.8±60.4), in male (384.7±62.4) at age (20-45) years they were divided into five groups: group one (G1) consisted of 30 hypothyroidism. The two group (G2) consisted of 30 patients with hyperthyroidism. And three group (G3) consisted of 30 healthy group, four group (G4) consisted of 30 patient with diabetes, and five group (G

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Publication Date
Sat Feb 02 2019
Journal Name
Journal Of The College Of Education For Women
Linguistic Analysis as Mean of Soliciting Patients concerns
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Publication Date
Sun Oct 02 2011
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Influence of Diabetes Mellitus on myocardial repolarization by measurement of QT variability Index
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Background: Various abnormalities in myocardial repolarization assessed by QT variability index (QTVI) in diabetics are associated with high risk to ventricular arrhythmia. The increase in cardiovascular morbidity and mortality appears to relate to the synergism of hyperglycemia with dyslipidemia, hypertension and obesity in addition to disturbed myocardial repolarization.
Objectives: The aim of the present study was to estimate and evaluate an index of myocardial repolarization instability (QTVI) in patients with DM on insulin or oral hypoglycemic drugs in comparison with healthy individuals.
Patients and Methods: The study was conducted on fifty six (56), middle-aged patients with DM of either sex in addition to age-matched healt

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