Background: Peripheral blood lymphocytes (PBL)of Rheumatoid arthritis (RA)patients have a property of phenotypic and functional activation. Glutathione S- transferase pi (GSTπ) has been implicated in playing an important role in the initiation and progression of cellular activation.
Objectives: To determine the percentage of cellular expression of GSTπ in the lymphocytes of RA patients in comparison with controls and to explore the relation between its cellular expression and disease activity pattern.
Patients and Methods: This prospective study included46 RA patients and 17 healthy controls. Blood samples were taken and from all subjects PBL were isolated and then smeared on slides. The cellular reactivity for GSTπ was determined by immunocytochemistry technique.
Results: This study found lower expression of GSTπ in the RA patients with a statistical significant difference with control group, while no statistical difference was found in RA with high and minimum disease activity groups. No correlation was observed between GSTπ with Disease Activity Score (DAS).
Conclusion: Although the decrease in the expression of GSTπ in PBLs was pronounced in RA patients, however it doesn’t correlate with disease activity state.
تضمّنت الاسطوغرافيا العثمانية التركية حول ثيمة محمية الج ا زئر في -
الفترة العثمانية مؤلفات صُبغت بعضيا بطابع الموالاة والتحيّز
تعدُّ حقوق الإنسان من الأمور التي حثّ الدين الإسلامي على احترامها ومن الأمور غير مسموح المساس بها ، وإنّ إغفالها أو إهمالها أو تضييعها يؤدي الى نتائج خطرة
The research aims to achieve a manuscript of Imam Al-Ghazali, may God have mercy on him, verify the attribution of this manuscript to the author, copy the text and serve it in a manner that suits the principles of scientific research in the investigation of manuscripts
The weakness of the central rule at the reign of Shah Sultan Hussain who is regarded as the last Shah who governed the Safawi state near to its falling at the hold of Afghan in 1722 which is the main and the real factor for the economic collapse. The tribes of trade have faced stealing and robbery actions which have been compressed to a very big extent. This action was not the responsibility of Shah alone,
المُستلخص:
يتناول هذا البحث موضوعاً يتركز في جانب تحديد مفهوم ومحتوى الإستراتيجية. وقد أشارت الأدبيات إلى عدد من المحاولات التي هدفت إلى تلمس مفهوم ومحتوى الإستراتيجية في منظمات الأعمال، غير أن تلك المحاولات- على الرغم من ندرتها- كانت تتسم بغلبة الأطر النظرية والتعبير عن المفهوم، بالإستناد إلى حوارات فكرية وإرهاصات ذات علاقة بمفهوم ومحتوى الإستراتيجية.
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... Show MoreThis study aims to studying of Person and organization’s environment fit in a sample of Private bank’s reflection in its basic dimensions (Person-organization fit ,Person-Job fit, Person-group fit and Person- Person-fit )in the Work Outcomes (job satisfaction, the intention to leave the job, Job Engagement, and organizational citizenship behavior ).
The questionnair’e has been used as a basic instrument to gather data , As well as personal interviews with some of the staff of the research sample of private banks which were represented by (5) and included banks (Bank of Assyria for investment, the North Bank for Finance and Investment , Bank of the Tigris
... Show Moreترك السلطان عبدالحميد الثاني بصماتهُ على أخاديد الزمان وعلى خارطة المشرق العربي الخاضع للسيطرة العثمانية أنذاك ، لكونهُ أهم شخصية أسلامية غير عربية واجهت الخطر الصهيوني ومحاولاتهم الإستيطانية في مشرق الوطن العربي ، على الرغم من صعوبة الظروف التي كانت تمر بها الدولة العثمانية داخليا ً وخارجيا ً، بما فيها من أطماع اقتسامها بين الاوربين ولذا سموها بالرجل المريض .