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Comparison between dexmedetomidine and propofol as sedatives for critically ill patients in intensive care units
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Background: Regarding using of sedation in the intensive care unit (ICU) should allow the patient to be more comfortable, calm, cooperative, and at the same time easily arousable without delay niether weaning nor prolonged mechanical ventilation.
Objective: The aim of my study is to compare the effect of dexmeditomidine Versus propofol for sedation and hemodynamic stability in a critically ill patient.
Patient and method: A randomized study of 44 patients admitted to ICU; 22 of them received dexmedetomidine and the other 22 patients received propofol for sedation. The level of consciousness, blood pressure, heart rate, respiratory rate and requirement for adjuvants to reach the target level of sedation were monitored for the first 12 hours.
Result: By applying Null hypothesis it was found that dexmedetomidine was significantly effective when compared with propofol for sedation with a p-value less than 0.001, while it was not significantly effective when compared with propofol plus adjuvant with p-value> 0.05.
Conclusion: Dexmedetomidine is effective as a sole sedative agent with haemodynamic stability without the need to add any adjuvant to it, while propofol cause hypotension and bradycardia if used alone to reach our target level of sedation, but can be used with adjuvant to reach our target of sedation and haemodynamic stability.
Keywords: Dexmedetomidine, Propofol, Sedation, ICU.

 

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Publication Date
Tue Nov 01 2016
Journal Name
Journal Of Engineering
Ultrafiltration and Reverse Osmosis Membranes for Treating Wastewater Effluent from Gas Turbine Power Plants using the Statistical Method of Taguchi
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A study on the treatment and reuse of oily wastewater generated from the process of fuel oil treatment of gas turbine power plant was performed. The feasibility of using hollow fiber ultrafiltration (UF) membrane and reverse osmosis (RO) membrane type polyamide thin-film composite in a pilot plant was investigated. Three different variables: pressure (0.5, 1, 1.5 and 2 bars), oil content (10, 20, 30 and 40 ppm), and temperature (15, 20, 30 and 40 ᵒC) were employed in the UF process while TDS was kept constant at 150 ppm. Four different variables: pressure (5, 6, 7 and 8 bar), oil content (2.5, 5, 7.5 and 10 ppm), total dissolved solids (TDS) (100, 200,300 and 400 ppm), and temperature (15, 20, 30 and 40 ᵒC) were mani

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Publication Date
Fri Jun 24 2022
Journal Name
Iraqi Journal Of Science
Study of the Effect of Raphanus Sativus, Urtica dioica and Curcuma longa Plant Extracts for Pollution Treatment by Fish's Provender
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This study was conducted to estimate the activity of crude extracts of the horseradish and nettles, turmeric plant and a combination of these combined plants extracts for the treatment of heavy metal pollution like zinc and cobalt that accumulate in fish by adding them to fish provender. This experiment was carried out during the September, October, November months, by using 40 gold fish that distributed in five basins, the heavy metals ratio (zinc and cobalt) were determined in the bodies of fish before the pollution in each basin. It has been added salts of zinc and cobalt to the basins in order to getting the concentration ratio 10 mg/L for each of the metals in the basins water, after 14 days have been re-determining of the concentra

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Publication Date
Tue Dec 13 2011
Journal Name
Iraqi Journal Of Laser
Intra Cellular Fluorescence for Monitoring The Physiological Changes and Biostimulation of Yeast Irradiated with Low Power 532nm CW Nd:YAG Laser
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The purpose of this study is to investigate the biostimulation effect of 532 nm CW laser on the metabolism of Saccharomyces cerevisiae yeast. Cells were irradiated by 532 nm Nd:YAG laser using 0.153 W/cm2 power density at 30, 45, 60,180 and 300 seconds exposure times in their respective orders. Intrafluorescence parameters were measured by detection the autofluorescence intensity, proliferation rate and Imaging the fluorescent mitochondria using confocal laser scanning microscope. The results showed that the 30 and 45 second exposure times seem to have stimulated changes in the cells that led to increase proliferation, viability and mitochondrial activity. Autofluorescence of cells increased after 45 and 60 seconds exposure time. After 3

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Publication Date
Sun Dec 04 2011
Journal Name
Baghdad Science Journal
Effect of Magnetic Treatment of water for irrigation and seed Qualities of the Plant vegetative growth corundum oriandrum sativum of
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Cultured fruits of theCorundum Coriandrum sativum were sown On 11/11 / 2008 in basins containing 15 kg of soil (Silty Loam) .Fruits were divided into two parts the first was soaked in normanl water and the second was magnetized for a period of 24 hours Irrigation was up to (75% of capacity field.Two types of water (normal water and magnetized water)with three repetitions were used the access to magnetic water was supplied from a special electric device. Recorded measurements were plant height the number of stems / plant, weight of plant, number of flowers, 1000 seed weight) during the cultivation period, which ended on 11/5/2009. Results indicated the absence of any effect of magnetic water on plant growth of Fenugreek while seeds tre

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Publication Date
Tue Jun 01 2021
Journal Name
Journal Of Engineering
A Comparative Study of a Moving Bed Biofilm Reactor and Bio-shaft Technology for a Wastewater Treatment Process: A review
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In addition to the primary treatment, biological treatment is used to reduce inorganic and organic components in the wastewater. The separation of biomass from treated wastewater is usually important to meet the effluent disposal requirements, so the MBBR system has been one of the most important modern technologies that use plastic tankers to transport biomass with wastewater, which works in pure biofilm, at low concentrations of suspended solids. However, biological treatment has been developed using the active sludge mixing process with MBBR. Turbo4bio was established as a sustainable and cost-effective solution for wastewater treatment plants in the early 1990s and ran on minimal sludge, and is easy to maintain. This

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Publication Date
Thu Mar 30 2023
Journal Name
Iraqi Journal Of Science
Electrochemical Study for the Effect of Simvastatin and Atorvastatin on Coenzyme Q10 by Differential Pulse Polarography Using Mercury Drop Electrode
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Statin drugs act by inhibiting the enzyme HMG-CoA reductase which is responsible for manufacture of cholesterol and the biosynthesis essential energy production Co-factor (Coenzyme Q10). The aim from this research includes study the effect of statin drugs (Simvastatin and Atorvastatin) on the Coenzyme Q10 using differential pulse polarographic technique at a dropping mercury electrode (DME) and in a mixture of [4:1] methanol-phosphate buffer of pH7.0 as supporting an electrolyte. Prior to this, the behaviors of Simvastatin, Atorvastatin and Coenzyme Q10 were studied separately in their solvents. The half-wave potential (E1/2) of Co Q10 were -0.31volt and -1.37Volt, -1.33 Volt for simvastatin and atorvastatin respectively. A mixture of Co

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Publication Date
Sun Jan 20 2019
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Synthesis, Antibacterial and Antifungal Activities for Novel Derivatives of 2,2'-(((1-benzylbenzoimidazol-2-yl)methyl)azanediyl)bis(ethan-1-ol)
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The compound 2,2'-(((1H-benzo(d)imidazol-2-yl)methyl)azanediyl)bis(ethan-1-ol) was reacted with benzyl bromide to afford compound (1) which used as row material to prepare a series of compounds through condensation reaction, the starting compound were reacted with tosyl chloride to protect the OH group  to afford compound 2, then reacted benzyl bromide to produce compound (2), then the compound (2) treated with three compounds ( 2-mercaptobenzthiazole, 2-mercaptobenimidazol and 2-chloromethyl benzimidazole) to form compounds 3a,b, 4a,b and 5a,b respectively. In the another step the click reaction of compound 2,2'-(((1H-benzo(d)imidazol-2-yl)methyl)azanediyl)bis(ethan-1-ol) with Propargyl bromide produce compound  6  which

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Publication Date
Wed Oct 04 2023
Journal Name
History Of Medicine
Theoretical Biological Activities and Docking studies of new amino-acids Derivatives of Oseltamivir for The Treatment of Coronavirus Disease 2019
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Antiviral medications may be the best choices for COVID-19 treatment until particular therapeutic treatments become available. Tamiflu (oseltamivir) is a neuraminidase inhibitor licensed for the management and defense against influenza types A and B. Oseltamivir-based medication combinations are currently being used to treat COVID-19 patients who also have the new coronavirus 1 SARS-CoV-2. 1 Oseltamivir administration was related with a less time spent in the hospital, quicker recovery 1 and discharge, and a decreased mortality rate. Docking is a modern computational method for identifying a hit molecule by assessing the binding ability of molecular medicines within the binding target pocket. In this work, we chose 21 ligand compounds that

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Publication Date
Tue Nov 01 2022
Journal Name
Journal Of Photochemistry And Photobiology B: Biology
High efficiency of Ag0 decorated Cu2MoO4 nanoparticles for heterogeneous photocatalytic activation, bactericidal system, and detection of glucose from blood sample
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Publication Date
Mon May 01 2017
Journal Name
Journal Of Nuclear Medicine
Capability of a novel small field of view hybrid gamma camera (HGC) for sentinel lymph node and small organ imaging
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Objectives: Small field of view gamma detection and imaging technologies for monitoring in vivo tracer uptake are rapidly expanding and being introduced for bed-side imaging and image guided surgical procedures. The Hybrid Gamma Camera (HGC) has been developed to enhance the localization of targeted radiopharmaceuticals during surgical procedures; for example in sentinel lymph node (SLN) biopsies and for bed-side imaging in procedures such as lacrimal drainage imaging and thyroid scanning. In this study, a prototype anthropomorphic head and neck phantom has been designed, constructed, and evaluated using representative modelled medical scenarios to study the capability of the HGC to detect SLNs and image small organs. Methods: An anthropom

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