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Acute Gastrointestinal radiation toxicities in pelvic radiation therapy; types, grade and frequency
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Background: quality of life of cancer survivors is adversely impacted by bowel toxicity; result from pelvic radiation therapy. In the UK, 12000 patients are treated with radiation therapy for pelvic cancer, mostly with curative intent; this carries a considerable risk for normal surrounding tissues side effects.
Objective: the aim of this study was to determine the frequency, types and grade of acute gastrointestinal toxicity in radical pelvic radiation therapy in our patients so that a comparison could be made with the Western countries.
Patients and Methods: a prospective analytic study was carried out in Radiotherapy department / Oncology teaching hospital / Medical city complex, from the 2nd of January to the 30th of April 2016. A total of 53 patients with histologically confirmed uterine, cervical, rectal, urinary bladder or prostatic cancer, treated by radical radiation therapy, were enrolled in the study. Patients were assessed for the frequency, types and grade of acute gastrointestinal toxicities according to grading criteria of CTC (Common Toxicities Criteria), at the start, during and at the end of the treatment. The data was analyzed by the Statistical Package for Social Sciences (SPSS 20).
Result: out of 53 patients, 60.37% (32) were female and 39.62% (21) were male. Endometrial cancers represent 30.18% of the cases, cervical cancers were 24.52%, and rectal cancers 11.32%, urinary bladder cancers 24.52% and prostatic cancers were 9.43% of the total cases. Diarrhea was present in 50.9% of the patients; nausea and vomiting were present in 22.6% for each. The majority had grade 1 toxicities and only 2 patients developed grade 3 diarrhea (4.7%).
Conclusion: The type and incidence of acute gastrointestinal toxicities in pelvic radiation therapy were mostly related to; Radiation dose, a combined used of chemotherapy with radiation therapy and surgery.

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Publication Date
Tue Mar 30 2021
Journal Name
Iraqi Journal Of Science
Assessment of Histopathological Changes in the Liver and Spleen of Mice Infected with Salmonella typhi Following Treatment with Ciprofloxacin
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This study evaluated the toxicity of ciprofloxacin to spleen and liver when used for the treatment of mice infected with S. typhi for seven days. The dose concentration used in these experiments was 100mg/kg. Mice were divided into two groups . The first group (negative control) was not given ciprofloxacin, but rather a sterile phosphate buffer solution (PBS) as an alternative. Ciprofloxacin was administered to the second group. After seven days , the animals were sacrificed and organs (liver and spleen) were collected . The histopathological examination showed normal hepatocytes in the liver  and normal structure of  spleen cells in animals of control group . However, the treated group showed dilated and congested blo

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Publication Date
Sun Jun 05 2016
Journal Name
Baghdad Science Journal
Development of an Eco-Friendly Method for Iron Extraction and Determination in Pharmaceuticals Using Ciprofloxacin Drug as Chelating agent
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A method is developed for the determination of iron (III) in pharmaceutical preparations by coupling cloud point extraction (CPE) and UV-Vis spectrophotometry. The method is based on the reaction of Fe(III) with excess drug ciprofloxacin (CIPRO) in dilute H2SO4, forming a hydrophobic Fe(III)- CIPRO complex which can be extracted into a non-ionic surfactant Triton X-114, and iron ions are determined spectrophotometrically at absorption maximum of 437 nm. Several variables which impact on the extraction and determination of Fe (III) are optimized in order to maximize the extraction efficiency and improve the sensitivity of the method. The interferences study is also considered to check the accuracy of the procedure. The results hav

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Publication Date
Mon Apr 03 2023
Journal Name
Journal Of Educational And Psychological Researches
Challenges Faced by Families of Children with Intellectual Disabilities and Its Effect on the Psychological Health in the Asir
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Abstract

This research aims to identify the challenges faced by families of children with intellectual disabilities and to identify the impact of the challenges facing them on the mental health of their children with intellectual disabilities. Based on the following questions: What is the nature of the challenges faced by families of children with disabilities and how do these challenges affect the mental health of their children with intellectual disabilities? The study was conducted on a sample of four families of six children with intellectual disabilities, depending on the degree and type of disability. To achieve the study's objectives, the qualitative approach was used, Because of the importance of accessin

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Publication Date
Mon Sep 25 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Bio Chemical Study of Antithyroid Peroxidase Auto Antibodies , Magnesium and Cobalt in Hyperthyroidism Patients From Different Regions of Iraq.
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Sixty hyperthyroidism patients aged (20-45) years from different parts of Iraq , (20) from the North , (20) from Baghdad , (20) from the South of Iraq , and (20)control were tested for the presence of antithyroid peroxidase antibody(Tpo-Ab)and for Mg and Co levels in their sera.

 

The results revealed a significant increase in (Tpo-Ab) in all patients group from the different parts of Iraq compared to control , also a  significant increase in (Tpo-Ab) for  the group from  North compared to other parts.

 

A significant decrease in Mg and Co levels in sera of patients from all parts of Iraq compared to control values , while no significant differences among patient groups were notice

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Publication Date
Thu Nov 01 2018
Journal Name
Iraqi National Journal Of Nursing Specialties
Assessment of Nurses Implementation of Universal Precautions in the AIDS Wards of Ibn-Zuheir and Ibn- Al- Kahteeb Hospitals
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A descriptive study was conducted at two Epidemic Hospitals in Baghdad from 1st of August( 2003) to 1st of October (2004) in order to identify the nursing staff working in AIDS word to implementation of universal precautions for patients with AIDS and relation to some variable. The sample is consisted of (50) nurses who are working in AIDS ward in Ibn- Zuheir and Ibn- Al- Kahteeb Hospitals. Instruments consist of (20) items related with demographic characteristics of nurses and universal precautions items . Validity of the instrument was established through a panel of( 4) experts in specific fields . Descrip

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Publication Date
Sun Dec 22 2019
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Assessment of Causality, Severity and Seriousness of Adverse Event Following Immunization in Iraq: A Retrospective Study Based on Iraqi
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Immunization is one of the most cost-effective and successful public health applications. The results of immunization are difficult to see as the incidence of disease occurrence is low while adverse effects following the immunization are noticeable, particularly if the vaccine was given to apparently healthy person. High safety expectations of population regarding the vaccines so they are more prone to hesitancy regarding presence of even small risk of adverse events which may lead to loss of pub

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Publication Date
Thu Dec 15 2022
Journal Name
Journal Of Baghdad College Of Dentistry
Assessment of serum levels of monocyte chemoattractant protein 1 (MCP 1) in patients with periodontitis and atherosclerotic cardiovascular disease
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Background: Monocyte chemotactic protein-1 (MCP-1) is a chemokine expressed by inflammatory and endothelial cells. It has a crucial role in initiating, regulating, and mobilizing monocytes to active sites of periodontal inflammation. Its expression is also elevated in response to pro-inflammatory stimuli and tissue injury, both of which are linked to atherosclerotic lesions. Aim of the study: To determine the serum level of MCP-1 in patients with periodontitis and atherosclerotic cardiovascular disease in comparison to healthy control and evaluate the biomarker's correlations with periodontal parameters. methods: This study enrolled 88 subjects, both males and females, ranging in age from 36-66 years old, and divided into four groups: 1<

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Publication Date
Sun Apr 09 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Preparation of One of Metformin Derivatives and Study Its Effect on Some Biochemical Parameters in Blood Sera of Rabbits
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   This study aimed to synthesize a novel amide prodrug of metformin with aspirin by amide bond. The structure was characterized by (FTIR, 1H-NMR, 13C-NMR and CHNO) ,Purification of the prepared compound was using column chromatography.          Using of 40 rabbit having the same weight and devided into 4 groups (4x10) the first group (G1): (the control healthy group) was given drink water and didn’t give any material, second group(G2):( the control infected group) was given hydrogen peroxide concentration  % 0.5 until infecting diabetes  mellitus,  third group(G3): was given hydrogen peroxide concentration as in (G2) and ( 250 mg/kg) of aspirin and (348.8 mg/kg

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Publication Date
Mon Jan 01 2024
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Assessment of Depression among IBD patients in Gastroenterology and Hepatology Specialized Hospital, Medical City, Iraq using the PHQ-9
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Background: The management of patients with inflammatory bowel disease (IBD) must take mental health into account because it might be difficult to find the best therapies and mental health resources. Anxiety and depression are the two psychological illnesses that IBD patients experience most frequently. The growing incidence of these mental illnesses encourages mental screening of every IBD patient at the initial session. There are easy-to-use, scientifically effective screening techniques for mental health issues. As important as or even more so than a therapy modality may be psychological techniques.

Objective: To assess the level of depression among IBD patients in the Gastroenterology and Hepa

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Publication Date
Thu Jun 08 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Theoretical Calculations of the Electron Transport Parameters in CH4-Ar and CH4-Ne Mixtures Gases Using Monte Carlo Method
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    The result of concentration varying of mixture methane with argon and neon gas are believed to study the change in electrons energy distribution function and then the change of the electrons transport parameters including the drift velocity, the mean energy, characteristics energy and diffusion coefficient. In the present work,a contemporary developed computer, simulation program known as Bolsig+ is being used for calculating the electron transport parameters.
 

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