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Acute Gastrointestinal radiation toxicities in pelvic radiation therapy; types, grade and frequency
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Background: quality of life of cancer survivors is adversely impacted by bowel toxicity; result from pelvic radiation therapy. In the UK, 12000 patients are treated with radiation therapy for pelvic cancer, mostly with curative intent; this carries a considerable risk for normal surrounding tissues side effects.
Objective: the aim of this study was to determine the frequency, types and grade of acute gastrointestinal toxicity in radical pelvic radiation therapy in our patients so that a comparison could be made with the Western countries.
Patients and Methods: a prospective analytic study was carried out in Radiotherapy department / Oncology teaching hospital / Medical city complex, from the 2nd of January to the 30th of April 2016. A total of 53 patients with histologically confirmed uterine, cervical, rectal, urinary bladder or prostatic cancer, treated by radical radiation therapy, were enrolled in the study. Patients were assessed for the frequency, types and grade of acute gastrointestinal toxicities according to grading criteria of CTC (Common Toxicities Criteria), at the start, during and at the end of the treatment. The data was analyzed by the Statistical Package for Social Sciences (SPSS 20).
Result: out of 53 patients, 60.37% (32) were female and 39.62% (21) were male. Endometrial cancers represent 30.18% of the cases, cervical cancers were 24.52%, and rectal cancers 11.32%, urinary bladder cancers 24.52% and prostatic cancers were 9.43% of the total cases. Diarrhea was present in 50.9% of the patients; nausea and vomiting were present in 22.6% for each. The majority had grade 1 toxicities and only 2 patients developed grade 3 diarrhea (4.7%).
Conclusion: The type and incidence of acute gastrointestinal toxicities in pelvic radiation therapy were mostly related to; Radiation dose, a combined used of chemotherapy with radiation therapy and surgery.

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Publication Date
Fri Jan 01 2021
Journal Name
E3s Web Of Conferences
Experimental Investigation of Bearing Capacity of Screw Piles and Excess Porewater Pressure in Soft Clay under Static Axial Loading
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In this study, the behavior of screw piles models with continuous helix was studied by conducting laboratory experimental tests on a single screw pile that has several aspect ratios (L/D) under the influence of static axial compression loads. The screw piles were inserted in a soft soil that has a unit weight of 18.72 kN/m3 and moisture content of 30.19%. Also, the soil has a liquid limit of 55% and a plasticity index of 32%. A physical laboratory model was designed to investigate the ultimate compression capacity of the screw pile and measure the generated porewater pressure during the loading process. The bedding soil was prepared according to the field unit weight and moisture content and the failure load was assumed correspondin

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Publication Date
Wed Nov 30 2022
Journal Name
Iraqi Journal Of Science
Paleoclimatic Insights on the Paleocene-Eocene Thermal Maximum in Central Iraq, Based on Calcareous Nannofossils, Ostracoda and Geophysical Data
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    The Paleocene-Eocene Thermal Maximum (PETM) event, which represented a sudden and abnormal rise in temperature during the early Cenozoic Era, is regarded as one of the most important global geologic phenomena. Two important index microfossils (nannoplankton and Ostracoda) were utilised to understand and predict the paleoenvironment and describe the changes during this period. The basis of the study was 12 cutting samples taken from Aaliji and the lower part of Jaddala formations of a subsurface section of (Ba-8) borehole in central Iraq. Some geophysical data were used to determine the upper and lower contacts of the Aaliji Formation and define the shale rate in the studied formations. The micropaleontologic investigation reveals

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Publication Date
Thu Jan 13 2022
Journal Name
Journal Of Water And Land Development
A study of the climate and human impact on the future survival of the Al-Sannya marsh in Iraq
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Polish Academy of Sciences

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Publication Date
Tue Mar 15 2022
Journal Name
Journal Of Baghdad College Of Dentistry
Effect of Resin Infiltration and Microabrasion on the Microhardness of the Artificial White Spot Lesions (An in Vitro Study)
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Publication Date
Mon Jan 01 2018
Journal Name
Research Journal Of Pharmacy And Technology
Molecular Genetic variability in the D-loop region for females with Breast Cancer and the effect of the Chemotherapy
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Publication Date
Mon May 29 2023
Journal Name
Rawal Medical Journal
Comparative prospective study of knee pain in medial pararpatellar and transpatellar entry for interlocking nail fixation of tibia fracture
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Objective: To compare two insertion techniques of intramedullary interlocking nails (medial parapatellar versus intrapatellar insertion) in patients with tibial fractures. Methodology: This study was performed at Al-Kindy Teaching Hospital from August 2020 until March 2022. All 32 patients with tibial fractures (29 males and 3 females) were included for tibial closed nail fixation and then followed up for 6 months. We categorized these patients into two groups; Group A (16 patients), those treated by medial parapatellar insertion of an interlocking nail, and Group B (16 patients) with transpatellar tibial nail insertion. All patients were treated by the same surgical team. Results: The range of movement in two weeks (from extension

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Publication Date
Tue Feb 28 2023
Journal Name
Iraqi Journal Of Science
Correlation Between Gene Expression of Interferon Regulatory Factor-5 and Disease Activity Index in Systemic Lupus Erythematosus Iraqi Patients
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      Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease characterized by elevated levels of circulating anti-nuclear autoantibodies and interferon-alpha (INFs-α). Interferon regulatory factor-5 (IRF5) plays an important role in the induction of type I interferon and pro-inflammatory cytokines, and participates in the SLE pathogenesis. This study aimed to investigate the role of IRF5 gene expression levels in a sample of SLE Iraqi patients and its correlation with disease activity, and to identify its diagnostic ability as a biomarker reflecting disease activity. Blood samples were taken from 45 participants diagnosed with SLE cases classified according to the American College of Rheumatology (ACR) criteria. T

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Publication Date
Wed Aug 30 2023
Journal Name
Iraqi Journal Of Science
Effect of Salinity Stress on Oxidative Stress Parameters and the Activity of Antioxidant Enzymes in Eight Durum Wheat Genotypes
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     This study was carried out at the Tissue Culture Laboratory, which belongs to the General Commission of Biotechnology, in order to evaluate the influence of NaCl-induced salinity stress on some oxidative parameters (MDA and H2O2) and antioxidant enzymes (CAT, APX, and SOD) in eight durum wheat genotypes (Doma1, Bouhoth11, Cham3, Bezater, Cham5, Aghamatales, Icaverve, and Icamber) in vitro, to determine the most salinity tolerant genotypes. Salinity stress was applied by adding different levels of NaCl to the growing medium (0, 50, 100, and 150 mM). The experiment was laid according to a complete randomized design (CRD) with sixteen replicates. Increasing

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Publication Date
Wed Oct 20 2021
Journal Name
Journal Of Engineering Research
Effect of several patterns of floating stone columns on the bearing capacity and porewater pressure in saturated soft soil
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One of the common geotechnical problems is the construction on soft soil and the improvement of its geotechnical properties to meet the design requirements. A stone column is one of the well-known techniques used to improve the geotechnical properties of soft soils. Sometimes thick layers of soft soil imposed the designer to use floating stone columns for improvement of such soil; in this case, the designer will be lost the end bearing of the stone column. In this study, the effects of several patterns of floating stone columns distribution under footing on the bearing capacity of soil and the distribution of excess porewater pressure are investigated. The soft soil used in this study has a very low undrained shear strength (cu) of

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Publication Date
Tue Jan 01 2019
Journal Name
Therapeutic Advances In Drug Safety
Deferasirox in thalassemia: a comparative study between an innovator drug and its copy among a sample of Iraqi patients
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Background:

The health care industry is witnessing an increasing trend in the use of generic medicines because of their presumed low cost compared with innovator medicines. The aim of this study was to determine and compare the performance of the copy drug Osveral®and its innovator drug deferasirox (Exjade®).

Methods:

A prospective observational study including 223 patients receiving the branded medicine Exjade®and 101 patients receiving the copy Osveral®was carried out. Data were assessed for a 1-year period and included clinical symptoms, serum ferrit

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