Background: Colorectal cancer (CRC) is the third most prevalent cancer worldwide with 1.80 million new
cases and 862,000 deaths in 2018. Depending on the stage, upfront surgery is the main form of treatment,
followed by adjuvant chemotherapy. Many drugs were approved by the U.S. Food and Drug Administration
for the treatment of CRC, one of which is Capecitabine. During cancer treatment, patient-reported symptoms
and quality of life parameters can provide additional information to evaluate and compare the efficacy and
toxicity of the treatments. Despite the importance of this issue, there is no published data that evaluates this
vital parameter in Iraqi patients receiving anti-cancer drugs, in general, or those on Capecitabine, in particular.
Objective: To evaluate the relationship between quality of life in capecitabine-treated colorectal cancer
patients and their sociodemographic characteristics as well as drug-related adverse effects.
Methods: A cross-sectional, open-label study was conducted at Al-Amal and Oncology Teaching Hospitals
in Baghdad during the period from November 2021 to June 2022. A convenient sampling method was adopted
to enrol patients in the current study. Quality of life assessment was performed using the European
Organization for Research and Treatment of Cancer quality of life questionnaire (QLQ-C30). Microsoft Excel
2019 and the Statistical Package for the Social Sciences (SPSS, Version 25) were used for data entry and
analysis. The descriptive analysis focused on frequencies and percentages. Continuous variables were
presented as (mean ± Standard Deviation). Categorical data were presented as proportions and the Chi-squared
test was used to study the associations between variables. The level of significance was considered at P≤0.05.
Results: A total of 102 patients were enrolled in the current study. Generalized fatigue was the most common
adverse event (63.7%) of participants. Only 6.9% of participants had abnormal renal function tests. Some
capecitabine-treated patients had good quality of life, others did not.
Conclusion: The quality of life of capecitabine-treated colorectal cancer patients seems to be sensitive to their
sociodemographic characteristics and adverse effects of the drug
The modern business environment has witnesses tremendous developments as a result of the globalization of markets and economic openness and technological as well as the acquisition of the issue of corporate governance of great importance regarding it as one of the global innovations trends of control provisions on the management of companies as result of these developments ,increasing on competition between economic unit ,thus a decrease in market share because they do not take into account the response to the requirements of customers ,which kept her to search a modern management accounting methods to help them keep up with the changes and the availability of information for the various adminis
... Show MoreCoronavirus 2019 (COVID-19) pandemic led to a massive global socio-economic tragedy that has impacted the ecosystem. This paper aims to contextualize urban and rural environmental situations during the COVID-19 pandemic in the Middle East and North Africa (MENA) Region.
An online survey was conducted, 6770 participants were included in the final analysis, and 64% were females. The majority of the participants were urban citizens (74%). Over 50% of the urban residents significantly (
The place in which the person lives and his geographical and social environment have a great impact on building his personality, belief and culture, Islam has alerted the importance of the Muslim to make sure to choose the appropriate place in which he resides and dwells in that it is compatible with his religion and belief in order to ensure communication with Islamic knowledge in a way that enhances his belief Arabization occurs when a person makes himself an Arab by living the life of the Bedouins, and creates the morals of the Bedouins from the inhabitants of the Badia with its harshness, cruelty, ignorance and lack of understanding in religion and far from the sources of knowledge of Islamic knowledge. Blasphemy and polytheism, and
... Show MoreThis study aims to clarify areas of using information technology in accounting and its impact on the profession of auditors by reviewing the concept, types, areas and the importance of information technology and its implications on the audit profession as well as to clarify the extent of contribution of information technology in developing of procedures of the audit profession and what its requirement, also this study aims to enhance the theoretical side by identifying the views of a sample of auditors in Arab countries selected (Iraq, Syria, Jordan), for the extent of using of information technology in their work and level of their perception for the importance of that
The research aims to find out the impact of Lee’s cognitive strategy on the achievement of fifth-grade literary students in the module of history. The research community consists of the secondary female day schools of Al-Karkh Al-Oula Directorate General of Education. The size of the research sample comprises (45) female students of the fifth grade of the literary brunch, (21) students for the experimental group and (24) students for the control group. The researchers have chosen an experimental design with partial control to suit the current research and its goal. They used a unified tool to measure the achievement of female students, which consisted of (50) items characterized by sincerity and they extracted the stability of t
... Show MoreThis study was carried out in Artificial Insemination Center of Iraq to revealed FMD disease effect on some seminal attributer parameters of 14 imported Holstein bulls divided to three groups according to different reproductive efficiency (four High, five medium and five weak). Results showed that FMD disease had significant (P < 0.05) adverse effect on most seminal attributer parameters, mass, individual motility and sperm concentration / ml during post disease in first of two, four, all months of high, medium and weak semen quality bulls respectively .but semen volume didn’t influenced significantly with this disease. So semen collection should be suspended until resume normal fertility of sperm, after two, four month of high and
... Show MoreBackground: Bone regeneration in dehiscence and fenestration defect can be improved with the use of platelet rich fibrin (PRF) that provides a scaffold for new bone regeneration. This study was conducted to assess the effectiveness of PRF as a graft material and membrane in dehiscence and fenestration defects. Materials and Methods: This prospective clinical study included patients who received dental implants that demonstrated peri-implant defects which were augmented using Leukocyte- PRF (L-PRF) or Advanced-PRF (A-PRF). Twenty four weeks postoperatively the defect resolution and the density of regenerated bone were assessed by CBCT and re-entry surgery. The assessment also included measurement of primary and secondary implant stability
... Show MoreAnti-Toxoplasma gondii seropositive status among obese and diabetic patients has recently attracted substantial attention. The objective of this study was to assess the seropositive rate of T. gondii and its relation to high body mass index (BMI), diabetes, and metabolic syndrome among participants (n=100) who attended Al-Kadhimiya Teaching Hospital, Baghdad-Iraq. An observational analytical study was conducted from October 2019 to March 2020. Participants were divided into three groups based on their BMI; obese (n=38), overweight (n=32) and normal (n=30). In addition, they were divided into diabetic (n=45) and non-diabetic (n=55) based on clinical examination, laboratory examination, and medical interview. Another clas
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