Autism spectrum disorder (ASD) is a spectrum of behavioral anomalies
characterized by impairment in social interactions and communication deficits. A
potential role for immune dysfunction has been suggested in ASD. To test this
hypothesis, certain cytokines: IL-2, IL-10, IL-12, IL-17A and IFN-γ were
investigated in serum of all participants. The study includes: 39 child (male and
female) aged < 5 to10 years with confirmed diagnosis of autism using standard
assessment, age and gender matched 24 confirmed healthy children and 19 non
autistic siblings used as controls. Serum was isolated and cytokines were detected
using enzyme linked immunosorbent assay (ELISA). The observations indicate a
significant increas

Background: malignant pleural mesothelioma (MPM) is uncommon neoplasm arising from mesothelial cells of the pleura. The most important etiologic agent is typically related to exposure to minerals fibers such as asbestos and erionite. Computed tomography (CT) plays essential role in characterization, diagnosis and staging of MPM.
Objectives: to determine the value of CT scan in characterization of MPM and its impact on diagnosis, and staging of the disease with histopathological correlation.
Patients and methods: the CT scan of 27 patients who had diagnosed of MPM were retrospectively evaluated, additionally CT findings of histopathological subtypes were compared and determine staging of the disease according to their documented CT

Recently the polycystic ovary syndrome (PCOS) has been linked with DNA damage and genomic instability. Amis of this study to evaluated some parameters of genetic instability such as micronuclei and comet assay score in women with PCOS. Genotoxicity and cytotoxicity of DNA damage were evaluated by measured of micronuclei and comet assay in 25 patients with PCOS and 15 normal menstrual women as control group. The results showed higher significant differences in the level of micronuclei and comet score in patients with PCOS compared with normal women. We concluded that, the genetic instability more occurred in patients with PCOS when compared with control group.
Keywords: MN, comet assay, PCOS

Background: Retrograde Cardioplegia is a widespread method for myocardial protection in coronary bypass surgery and to abroad range of open heart surgical procedures in addition to antigrade Cardioplegia,
Objectives: Is to evaluate the use of retrograde cardioplegia and its advantages in coronary bypass surgery at Ibn Al-Nafees Teaching Hospital, Department of Cardiac Surgery,
Patients and methods: This is a retrospective study that was conducted at Ibn Al-Nafees Teaching Hospital from the first of January to the first of October 2015, fifty patients with coronary artery dieses were admitted to the hospital and coronary artery bypass graft (CABG) surgery was done under cardiopulmonary bypass using retrograde cardioplegic canula thr

Background: Coronary artery bypass graft is routinely performed on an arrested heart using cardiopulmonary bypass with aortic cross clamping and Cardioplegia. Off-pump coronary artery bypass graft (OPCABG) is being increasingly used in selected cases as an attempt to decrease morbidity and mortality.
Objective: The main objective of this study is to clarify those patients who are indicated for OPCABG despite it is surgically demanding technique and to evaluate the mortality and morbidity associated with such procedures.
Patients and methods: It is a retrospective study of 28 patients with coronary artery disease, in need for coronary artery bypass graft admitted and surgically treated at the Iraqi Centre fo

Background: carpal tunnel syndrome (CTS) a relatively common disease affecting ♀ more than ♂, usually at the age between 40 -60 , diagnosed by EMG & NCS, treated when moderate
to severe by surgical decompression of the median nerve.
Objective: To study the role of surgery in the management of CTS.
Patients & method: 124 patients collected from the neuro-surgical departments of the specialized surgical hospital from August 2001 till March 2007, all patients studied thoroughly
regarding age, sex, associated diseases, clinical features, EMG studies, surgery & out come & follow up for at least one year.
Results & discussion: there was around 2:1 ♀:♂ , with age predomena between 40-60

Background: Leukemia isba type of cancer of the blood or bone marrow that is characterized by an abnormal increase of white blood cells.

Background: Hodgkin disease was the first cancer in which the curative potential of combination chemotherapy was demonstrated. The affected patients are often young and there is a great potential for adding years of productive life by giving curative therapy even when the disease is advanced.
Objective: to describe the experience of the hematology unit,Baghdad Teaching Hospital, in the management of 40 adult patients with Hodgkin disease.
Patients and Methods: a retrospective cohort study of forty adult Iraqi patients with Hodgkin disease between 2005 and 2013 in the hematology unit. Patients were treated initially with 6-8 cycles of ABVD chemotherapy protocol (doxorubicine+ bleomycin+ vinblastin+ dacarbazine) , nine patients recei

Background: Autoantibodies to islet cell antigens are known predictors of type 1 diabetes and detected in latent autoimmune diabetes in adults.
Objectives: This study aimed to identify the metabolic and immunological disturbances in diabetic patients with positive and negative islet cell antibodies (ICAs)
Materials and methods: A total number of 235 known cases of diabetes mellitus type 1 (160) and type 2 diabetes (75) were admitted in the study. Serum ICA and immunoglobulins (IgA, IgM, IgG) as well lipid profile were measured.
Results: Positive ICAs was found in 40 out of 120 T1D (33.3%) and 28 out of 75 T2D (37.3%). All the patients were poorly controlled diabetes with the evidence of significant high