Preferred Language
Articles
/
iqjmc-1948
the Immunohistochemical Study of Stathmin-1 as A Prognostic factor In Non-small cell lung carcinoma
...Show More Authors

Abstract   

 

Background

Stathmin1 (also known as metablastin) is a major microtubule-depolymerizing protein that involved in cell cycle progression and cell motility.

 Stathmin1 has been found to be up-regulated in some cancers and correlated with cell differentiation and proliferation.  

Stathmin1 is a major cytosolic phosphoprotein that regulates microtubule dynamics and is associated with malignant phenotypes in various cancers, including non-small cell lung cancer.

 

Objective

 To evaluate the role of Immunohistochemical expression of stathmin1 in non-small lung carcinoma and its correlation to different prognostic factors or parameters.

 

Materials and methods

This retrospective study carried on formalin fixed paraffin embedded surgical specimens of lung tumors  Applying the Immunohistochemical techniques by using the primary antibodies to stathmin1, statistical analysis done and assessment of correlation with different clinical and pathological parameters measured.

 

 Results

Fifty cases of Non-small lung carcinomas that 42% adenocarcinoma,44% squamous cell carcinoma 10% adenosequamous and 4% non-small lung carcinoma 84 % were Stathmin-1 positive.

 No significant correlation between Stathmin-1 expression with age and gender of patients but Stathmin-1 expression were correlated with parameters including type and grade of tumor.

High expression was noted in poorly differentiated tumors.

 

Conclusions

Measurement of stathmin1 level may be a beneficial prognostic biomarker for non-small lung tumors especially those of poorly differentiated tumors

Stathmin1 expression in non-small cell lung carcinoma significantly correlated with poor tumor differentiation and could be considered as independent prognostic factor.

Crossref
View Publication
Publication Date
Tue Apr 01 2014
Journal Name
Journal Of The Faculty Of Medicine Baghdad
The effect of blood lead level on packed cell volume in a sample of Iraqi population.
...Show More Authors

Background: Low hemoglobin levels and lead exposure remain significant health issues in many parts of the world, often occurring together, however most of the researches concentrate on the effect of high levels of lead .This study aimed to demonstrate the effect of blood lead level on hemoglobin and packed cell volume (PCV).
Patients and Methods: Fifty eight adult volunteers were enrolled in this study with age range between 23 and 55 years, working in the different departments in medical college of Baghdad University. Whole blood was withdrawn in EDTA tubes. Hemoglobin and PCV were measured and blood lead level was estimated using blood lead testing system including lead care kit and lead care analyzer.
Results: After measuring bl

... Show More
View Publication Preview PDF
Crossref
Publication Date
Tue Jan 02 2007
Journal Name
Journal Of The Faculty Of Medicine Baghdad
An evaluation of methods of inducing sputum production in patient with suspected lung cancer
...Show More Authors

Background : the major focus of respiratory cytology is the diagnosis of lung cancer , carcinoma of the lung is now reported to be the most commonly diagnosed non- Cutaneous malignancy in the world. Iraq has faced the increase in incidence of this lethal type of cancer. Sputum cytology is a convenient method of screening and diagnosing primary epithelial tumor of the lung which is of many types include fresh smear ,Sacccomanno smear, and mailing container method.
Methods : Sputum cytological study was done on 50 patients suspected to have pulmonary carcinoma prepared by fresh smear method ,Saccomanno method ,and mailing container
method.One, two,or three samples taken from each patient.Slides were prepared

... Show More
View Publication Preview PDF
Crossref
Publication Date
Fri Jan 10 2025
Journal Name
Journal Of Baghdad College Of Dentistry
Assessment of the Immunohistochemical expression of EBV in oral lichen planus
...Show More Authors

Background: Oral lichen planus (OLP) is a chronic immunologic disease. The etiology of OLP is unknown, viral antigens (for example EBV) have been proposed as etiologic agents. OLP may get transformation to malignancy so research on the presence of these in OLP lesions seems to be necessary. The aim of this study was to evaluate EBV expression immunohistochemically in OLP. Materials and Methods: Tissue specimens of 30 formalin fixed, paraffin-embedded tissue Blocks histologically diagnosed oral lichen planus was performed to evaluate EBV expression. Results: Expression of EBV was detected in epithelium of (46.6%) in the study samples in (OLP). no statistically significant correlation was found with clinical parameters except for a significan

... Show More
View Publication Preview PDF
Publication Date
Mon Mar 07 2022
Journal Name
Journal Of Educational And Psychological Researches
The Structural Model of the Relationship between Emotional Creativity and Self-Efficacy among Students at the Preparatory Year Tabuk University
...Show More Authors

This research aimed to identify the structural model of the relationship between emotional creativity and self-efficacy among male and female students of the preparatory year at Tabuk University. The current study adopted the descriptive correlational approach, as it is appropriate to the nature of the study. The study tools contained (60) items that measure the relationship between emotional creativity and self-efficacy among the male and female students of the preparatory year at Tabuk University. The study sample was chosen by the stratified random method of the study community, where the study sample reached (183) male and female students of the preparatory year at the University of Tabuk. The results of the study showed that there a

... Show More
View Publication Preview PDF
Publication Date
Sun Mar 20 2016
Journal Name
Al-academy
The Impact of using the strategy of shape (V) on the Achievement of the students of the Department of Artistic Education: كريم حواس علي، نجلاء خضير حسان
...Show More Authors

This research aim at finding out the impact of using the strategy of shape V on the achievement of the students of the Department of Artistic Education in the subject of "Principles of scientific Research ". This strategy is one of the cognitive strategies used in this topic . To verify the aim of the research ,the two researchers have put the following null hypothesis:-There are no significant differences on the level of 0,05 among the average degrees of the students of the experimental group in their answers on the topics of the pre and post cognitive achievement tests of the subject of "principles of scientific Research " . The two researchers have adopted the experimental approach which consists of one group . the population of the r

... Show More
View Publication Preview PDF
Crossref
Publication Date
Tue Aug 01 2023
Journal Name
Baghdad Science Journal
Spectrophotometric Determination of Micro Amount of Chromium (III) Using Sodium 4-((4,5-diphenyl-imidazol-2-yl)diazenyl)-3-hydroxynaphthalene-1-sulfonate in the Presence of Surfactant, Study of Thermodynamic Functions and Their Analytical Applications
...Show More Authors

          Using sodium4-((4,5-diphenyl-imidazol-2-yl)diazenyl)-3-hydroxynaphthalene-1-sulfonate (SDPIHN) as a chromogenic reagent in presence of non-ionic surfactant (Triton x-100) to estimate the chromium(III)  ion if the wavelength of this reagent 463 nm to form a dark greenish-brown complex in wavelength 586 nm at pH=10,the complex was stable for longer than 24 hours. Beer's low, molar absorptivity 0.244×104L.mol-1.cm-1, and Sandal's sensitivity 0.021 µg/cm2 are all observed in the concentration range 1-11 µg/mL. The limits of detection (LOD) and limit of quantification (LOQ), respectively, were 0.117 µg/mL and 0.385µg/mL. (mole ratio technique, job's method) were employed to

... Show More
View Publication Preview PDF
Scopus (3)
Scopus Crossref
Publication Date
Mon Jan 01 2018
Journal Name
مجلة كلية التربية للبنات/ مجلة علمية ثقافية تربوية محكمة
الاتجاهات الموضوعية للبحوث المنشورة في مجلة كلية القانون / جامعة بغداد
...Show More Authors

Publication Date
Thu Jan 01 2009
Journal Name
Journal Of Educational And Psychological Researches
المفاهيم البيئية لدى طالبات كلية العلوم للبنات في جامعة بغداد
...Show More Authors

مشكلة البحث

    لقد تفاقمت مشكلة تلوث البيئة في السنوات الأخيرة من العقد الأخير والعقد الأول من القرنين العشرين والحادي والعشرين على التوالي بشكل يلفت النظر. إذ انتشر الاستعمال غير العقلاني للموارد الطبيعية من مياه ملوثة وسكن غير صحي وغير ملائم وسؤ التغذية وظروف الصحة العامة الرديئة وانتشار العوادم التي تحدثها المركبات والمولدات التي انتشرت في أحياء المدن العراقية لتزوي

... Show More
View Publication Preview PDF
Publication Date
Sun Jul 04 2010
Journal Name
Journal Of Educational And Psychological Researches
تقويم اداء تدريسيي دورات التأهيل التربوي واللغوي في جامعة بغداد
...Show More Authors

ان بناء اية حضارة يمثل جهداً انسانياً يشترك فيه كل الافراد والمؤسسات ويستلزم حشد القدرات لاسيما النخبة التي توجه الجهود وتعمل على الاستخدام الامثل للموارد في اطار حركة منظمة للمجتمع تنتج وسائلها وتحقق اهدافها ، وان حركة التاريخ والواقع تظهر ان التدريسي الجامعي هو صفوة النخبة والجامعة هي بؤرة المعرفة المؤسسية . ( عبود 2008 : 12 )                         &

... Show More
View Publication Preview PDF
Publication Date
Tue Apr 01 2008
Journal Name
Al-academy
واقع تعليم الموسيقى وتعلمها في كلية الفنون الجميلة/ جامعة بغداد
...Show More Authors

كَشفت التنقيبات في مدن العراق القديم كالوركاء وماري عـن بقايا أبنية المدارس الموسيقية ( ) . وفي العصر السومري الحديث ( 2000 – 1950 ق. م. ) حُفِظ ما يؤيد وجود مواد المنهج الموسيقي النظري والعملي لعملية التعليم في مدرسة المعبد أو القصر الملكي ، إضافة لبعض اللقى الآثارية كآلات فخارية خاصة بالطفل ، والتي بوساطتها كان يتم تعليم الطفل في البيت ( ) . واحتلت الموسيقى مكانة هامة في حضارات الشرق المختلفة المُتزامنة مع حضارات و

... Show More
View Publication Preview PDF