Preferred Language
Articles
/
iqjmc-1888
Detection of BRAFV600E Biomarker In Patients With Colorectal Cancer Using Immunohistochemical Techniques / Clinico-Pathological Study
...Show More Authors

Background :

Colorectal cancer (CRC) is the 4th common gastrointestinal cancer. (BRAFV600E) is a member of RAF family of serine/threonine protein kinases that function to regulate the (MAPK) / (ERK) pathway. BRAFV600E mutated CRC are associated with right-sided primary tumors, older women and high-grade tumors.

Aims of the study:

Study the immunohistochemical expression of BRAFV600E biomarker in a sample of Iraqi patients with colorectal cancer and the correlation of BRAFV600E expression with other clinicopathological variables such as patient's age and tumor grade.

 

Materials and Methods :

in this prospective study a total of 90 colorectal cases of a sample of Iraqi patients were collected from teaching labs of AL-Yarmouk Teaching Hospital including 60 cases of colorectal carcinoma and 30 cases of colorectal adenoma.

 

Result: BRAFV600E biomarker was positive in 16.6% of colorectal carcinoma group and negative in colorectal adenoma group.

 

Conclusions:

BRAF expression was higher in older patients ages & higher tumor stages and there is no expression of BRAFV600E in adenoma cases.

 

 

Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Wed Jul 01 2015
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Experimental Study the role of LasA Protease of Pseudomonas aeruginosa in the Treatment of Bacterial Keratitis Caused by Staphylococcus aureaus
...Show More Authors

Background: LasA protease play a major role in the colonization of the bacteria to the cornea during bacterial keratitis by preventing other bacteria from colonization to the cornea, for example in the mixed infection with S. aureus the enzyme eradicate the bacteria by their lysis it and finally eliminate the competitive for P. aeruginosa bacteria.
Objective: To study the role of LasA protease of Pseudomonas aeruginosa in the treatment of experimental keratitis caused by S. aureus.
Patients and methods: One hundred - twenty clinical samples (corneal scraping) were collected from patients suspected with bacterial keratitis presenting to Ibn Al-Haitham Teaching Hospital from May 2013 until November 2013. The bacterial isolate of P. a

... Show More
View Publication Preview PDF
Crossref (1)
Crossref
Publication Date
Sat Sep 23 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Brain Tumor Detection Method Using Unsupervised Classification Technique
...Show More Authors

Magnetic  Resonance  Imaging  (MRI)  is  one  of  the  most important diagnostic tool. There are many methods to segment the

tumor of human brain. One of these, the conventional method that uses pure image processing techniques that are not preferred because they need human interaction for accurate segmentation. But unsupervised methods do not require any human interference and can segment   the   brain   with   high   precision.   In   this   project,   the unsupervised  classification methods have been used in order to detect the tumor  disease from MRI images.    These metho

... Show More
View Publication Preview PDF
Publication Date
Thu Oct 01 2020
Journal Name
Journal Of Engineering Science And Technology
Automatic voice activity detection using fuzzy-neuro classifier
...Show More Authors

Voice Activity Detection (VAD) is considered as an important pre-processing step in speech processing systems such as speech enhancement, speech recognition, gender and age identification. VAD helps in reducing the time required to process speech data and to improve final system accuracy by focusing the work on the voiced part of the speech. An automatic technique for VAD using Fuzzy-Neuro technique (FN-AVAD) is presented in this paper. The aim of this work is to alleviate the problem of choosing the best threshold value in traditional VAD methods and achieves automaticity by combining fuzzy clustering and machine learning techniques. Four features are extracted from each speech segment, which are short term energy, zero-crossing rate, auto

... Show More
View Publication Preview PDF
Scopus (4)
Scopus
Publication Date
Fri Nov 24 2023
Journal Name
Iraqi Journal Of Science
Edge detection for Diabetic Retinopathy using fuzzy logic
...Show More Authors

Diabetic retinopathy is an eye disease, because of pressure in eye nerve fiber. It is a major cause of blindness in middle as well as older age groups; therefore it is essential to diagnose it earlier. Some of the challenges are in the diagnosis of the disease is detection edges of the image, may be some important edges are missed outcome the noise around the corners.
Wherefore, in order to reduce these effects in this paper, we proposed a new technique for edge detection using traditional operators in combination with fuzzy logic based on fuzzy inference system. The results show that the proposed fuzzy edge detection technique better than of traditional techniques, where vascular are markedly detected over the original.

View Publication Preview PDF
Publication Date
Tue Nov 30 2021
Journal Name
Iraqi Journal Of Science
Modified Vegetation Detection Index Using Different-Spectral Signature
...Show More Authors

The Normalization Difference Vegetation Index (NDVI), for many years, was widely used in remote sensing for the detection of vegetation land cover. This index uses red channel radiances (i.e., 0.66 μm reflectance) and near-IR channel (i.e., 0.86 μm reflectance). In the heavy chlorophyll absorption area, the red channel is located, while in the high reflectance plateau of vegetation canopies, the Near-IR channel is situated. Senses of channels (Red & Near- IR) read variance depths over vegetation canopies. In the present study, a further index for vegetation identification is proposed. The normalized difference vegetation shortwave index (NDVSI) is defined as the difference between the cubic bands of Near- IR and Shortwave infrared

... Show More
View Publication Preview PDF
Scopus (7)
Crossref (3)
Scopus Crossref
Publication Date
Sat Feb 20 2010
Journal Name
Indian Journal Of Science And Technology
Investigation on picosecond laser ablation of dental material using FIB/SEM techniques
...Show More Authors

View Publication
Scopus (1)
Crossref (1)
Scopus Crossref
Publication Date
Mon Dec 18 2017
Journal Name
Al-khwarizmi Engineering Journal
Path Planning of an autonomous Mobile Robot using Swarm Based Optimization Techniques
...Show More Authors

This paper presents a meta-heuristic swarm based optimization technique for solving robot path planning. The natural activities of actual ants inspire which named Ant Colony Optimization. (ACO) has been proposed in this work to find the shortest and safest path for a mobile robot in different static environments with different complexities. A nonzero size for the mobile robot has been considered in the project by taking a tolerance around the obstacle to account for the actual size of the mobile robot. A new concept was added to standard Ant Colony Optimization (ACO) for further modifications. Simulations results, which carried out using MATLAB 2015(a) environment, prove that the suggested algorithm outperforms the standard version of AC

... Show More
View Publication Preview PDF
Crossref (18)
Crossref
Publication Date
Tue Apr 01 2014
Journal Name
Journal Of Economics And Administrative Sciences
Evaluation Age and Gender for General Census of the population in Iraq by using nonparametric Bayesian Kernel Estimators
...Show More Authors

The process of evaluating data (age and the gender structure) is one of the important factors that help any country to draw plans and programs for the future. Discussed the errors in population data for the census of Iraqi population of 1997. targeted correct and revised to serve the purposes of planning. which will be smoothing the population databy using nonparametric regression estimator (Nadaraya-Watson estimator) This estimator depends on bandwidth (h) which can be calculate it by two ways of using Bayesian method, the first when observations distribution is Lognormal Kernel and the second is when observations distribution is Normal Kernel

... Show More
View Publication Preview PDF
Crossref
Publication Date
Tue Mar 30 2021
Journal Name
Journal Of Economics And Administrative Sciences
Designing a Quality System using the Goals Programming Method -An Applied Research
...Show More Authors

Due to the continuous development in society and the multiplicity of customers' desires and their keeping pace with this development and their search for the quality and durability of the commodity that provides them with the best performance and that meets their needs and desires, all this has led to the consideration of quality as one of the competitive advantages that many industrial companies compete for and which are of interest to customers and are looking for. The research problem showed that the Diyala State Company for Electrical Industries relies on some simple methods and personal experience to monitor the quality of products and does not adopt scientific methods and modern programs. The aim of this research is to desi

... Show More
View Publication Preview PDF
Crossref
Publication Date
Wed Apr 01 2009
Journal Name
Journal Of The Faculty Of Medicine Baghdad
The Possible Cytoprotective Effects of Antioxidant Drugs (Vitamin E and C) Against the Toxicity of Doxorubicin in Breast Cancer Patients
...Show More Authors

Background: Breast cancer is the culmination of a multi-step process that occurs over a period of several years or decades and as a cause of death, is a salient "free radical" disease. Aim: The present study aims on investigating the possible protective role of antioxidant drugs (vitamins E and C) to cardiac cells against the oxidative stress induced damage during doxorubicin chemotherapy in patients with breast cancer.
Patients and methods: Thirty two patients with different stages of breast carcinoma attending to Baghdad Teaching Hospital and ten healthy control subjects with age range between (29-61) years, mean (43.6±1.37) were included in this study. The patients were randomized into 3 groups, they

... Show More
View Publication Preview PDF
Crossref