Background: Guillain-Barre syndrome (GBS) is the most common cause of acute motor paralysis in children where most of electrophysiological findings reveal demyelinating neuropathy. However, an axonal form of Guillain-Barre syndrome had been reported too.
Objectives: Assess the role of neurophysiological study (EMG and NCS) in the diagnosis of Guillain-Barre syndrome subtypes in children and estimate the frequency of subtypes whether demyelinating or axonal form of Guillain-Barre syndrome.
Subjects and methods: Two study groups of either sex was involved, thirty (30) Guillain-Barre patients with different ages and thirty(30) normal healthy subjects matched for age and gender served as control group. Each subject submitted to sensory and motor nerve conduction study (NCS) and electromyography (EMG) of both upper and lower limbs.
Results:The results of this study revealed that 24 (80%), 5 (16.7%), 1 (3.3%) had Acute inflammatory demyelinating polyneuropathy, Acute motor axonal neuropathy and Acute motor sensory axonal neuropathy respectively. The most affected age group was (3-6) years, and the majority of patients had a preceding infection in the past 3 months. Furthermore, 29 patients out of 30 had lost deep tendon reflexes and the H-reflex was absent in 22 (73.3%), however, the F-wave was absent in lower limbs more than upper limbs (46.6%) and (26.6%) respectively. The distal motor latency was abnormal in 121 (82.3%) nerves out of 147 total examined nerves.
Conclusion:Acute inflammatory demyelinating polyneuropathy (AIDP) is the most frequent subtype of GBS, the change in sensory and motor NCS parameters was higher in lower limbs than upper limbs. Proximal segments are more vulnerable to demyelination rather than intermediate or distal nerve segments.
The study area is part of the city of Samawa in Al Muthanna Governorate in southern Iraq. The study area is located to the west of Samawa city bounded by the north latitudes 31⁰11'-31o42' and east longitudes 44o58'- 45⁰16'and its groundwater resources are developed for supply and irrigation purposes. In order to evaluate the quality of groundwater in the study area, twenty three groundwater samples were collected and analyzed for physical and chemical parameters. Hydrochemical analysis showed that the groundwater of the study area is excessively mineralized and very hard. The increase in flow length of groundwater in the study area caused a change in water
... Show MoreMonocytes are considered a key mediator of inflammatory cytokine secretions during inflammation. This study evaluates CD 14 expression in gastritis tissue biopsies of H. pylori and none H. pylori gastritis. This cross-sectional study involved 60 gastritis patients that have been classified into H. pylori positive (n=30) and H. pylori negative (n=30). Formalin fixed paraffin embedded tissue blocks were sectioned and immune-peroxidase staining with anti-CD14, then compared between study groups and clinical parameters. The results showed a marked difference in the percentage of expression in mild and severe intensity of inflammation sub-groups, the results showed a higher percentage of CD14 immunoreactivity (18.29±5.84 vs. 10.2±3.89, p=0.
... Show MoreThis research mainly focuses on the preparation of chitosan-alginate Nanoparticle by ionotropic gelation method using calcium chloride and sodium alginate to form nanocomposites of CH-ALg, examine their antibacterial activity against multidrug resistance (MDR) bacteria, and evaluate the stability of chitosan-alginate formula in different biological fluids, including simulated gastric fluid (SGF) and intestinal fluid (SIF). The average diameter of particles size prepared was measured by an Atomic force microscope (AFM) and it was 61.91 nm. Otherwise, the nature of functional groups present in CH-ALg nanoparticle was investigated by Fourier transforms infrared (FTIR) analysis. The stability of synthesized CH-ALg nanoparticle was
... Show MoreThis research aims to develop transdermal patches of Ondansetron hydrochloride (OSH) with different types of polymers, ethyl cellulose and, polyvinyl pyrrolidone k30 in a ratio (3:0.5,3:1,3:2,2:1,1:1) with propylene glycol 20%w/w as a plasticizer. Prepared transdermal patches were evaluated for physical properties. The compatibility between the drug and excipients was studied by Differential scanning calorimetry (DSC), where there is no interaction between the drug and polymers. From the statistical study, there is a statistical difference between all the prepared formulations p<0.05. In-vitro Release study of transdermal patches was performed by using a paddle over the disc. The release profile of OSH follow
... Show MoreABSTRACT: BACKGROUND: The main goal of facelift surgery is to reduce the effect of aging by reposition of face soft tissue in to more youthful orientation. There are many methods for SMAS plication which had different design and vector of pull. AIM OF STUDY: To evaluate the effectiveness and longitivity of 7 shaped SMAS plication in facelift. PATIENT AND METHODS: From January 2020 to march 2021, 10 female patients with age (45-60) years were presented with facial sagging, those patients were subjected to subcutaneous facelift with 7 shaped SMAS plication with fat greft in Al-Shaheed Ghazi Al-Harri Hospital and Baghdad burn medical center at Baghdad medical complex. RESULTS: The average follow up period was 6 to 12 months. The mean operative
... Show MoreObjective: The aim of this study was to formulate and in vitro evaluate fast dissolving oral film of practically insoluble bromocriptine mesylate to enhance its solubility and to improve its oral bioavailability by avoiding first pass effect as well as to produce an immediate release action of the drug from the film for an efficient management of diabetes mellitus type II in addition to an improvement of the patient compliance to this patient- friendly dosage form. Methods: The films were prepared by the solvent casting method using hydroxypropyl methylcellulose of grades (E3, E5, E15), polyvinyl alcohol (PVA), pectin and gelatin as film-forming polymers in addition to polyethene glycol 400 (PEG400), propylene glycol (PG) and glycerin were
... Show MoreSix Bifidobacterium isolates, isolated from breast – feed infant faces on reduced de Man Rogosa and Sharp medium (MRS - C). Isolates identified to species level on the basis of : microscopical properties, biochemical tests, fructose-6-phosphate phosphoketolase enzyme(F6PPK) activity and carbohydrates fermentation profile. Results showed that B. adolescentis was the predominant species (B4,B5and B6),the other species were B. breve(B3),B. longum (B1), B. dentium(B2).
Strains were screened for their inhibitory effects against pathogenic bacteria shiga toxin producing E.coli(STEC)O157:H7 using agar – well diffusion method.B3 and B6 showed clear inhibitory actions toward STEC,22 mm and 15 mm diameter of inhibition zone srespectively. W
Provides the style of benchmarking the best possible use whenevaluating the performance and evaluation, as well as improved performance,due to its consistency with the principles of good evaluation of theperformance, an extension of the completion of several functions of the timeand cost less, thereby increasing the efficiency of the management of theinstitutions, especially institutions, the media, as it became public the future ofthe message sender to the same time Zaorosaúl new media is challenging thetraditional media of what distinguishes this new interactive media and mass ledto this transition . However, the media Aljdidhoosaúl traditional mediacontinue to coexist and reinforce each Menhmaalakhr, for his wealth offreedom of opin
... Show MoreThe groundwater evaluation has been carried out in Khanaqin area in Diyala governorate to the east of Iraq. The analyzed hydrochemical parameters such as pH, electrical conductivity, total dissolved solids as well as cations and anions are used to describe groundwater quality and its suitability for different purposes. The study area covers (1920) km2. According to hydrogeological investigation (43) water points were inventoried and water levels in wells were measured. (34) Wells were sampled during 2013-2014 during water surplus and water deficit periods. The studied area is divided groundwater aquifers into two main units, the unconfined and confined aquifers. The values of pH, electrical conductivity (EC) and total dissolve
... Show MoreThe non-specific response of immunity has developed as the initial barrier for human protection from invading pathogens, which comprises certain pathogen recognition receptors (PRR) for instance toll-like receptors (TLRs). Toll like receptor 2 (TLR 2) is capable of recognizing pathogen associated molecular patterns (PAMP) coded by Mycobacterium tuberculosis. To evaluate TLR 2 level in sera of pulmonary tuberculosis (TB) patients. About 120 subjects, involving 80 patients with pulmonary TB including 40 multiple drug resistance (MDR), 20 recently diagnosed pulmonary TB (RD) and 20 recurrent TB patients named as old cases (OC), in addition to 40 apparently healthy individuals were studied as control group. Sera from 68 TB patients
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