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The relationship between obesity and plasma level of factor V and fibrinogen

Background:  Obesity is a medical condition in which excess body fat has accumulated to the extent that it has an adverse effect on health. . It measured by BMI (body mass index), obesity is considered when the BMI is ≥ 30 kg/m2. It increases the risk of coronary heart disease, Diabetes Mellitus and Cancer. Chronic inflammation and impaired fibrinolysis in obesity may induce thrombosis.

Aim of study: assess the effect of BMI (body mass index) on plasma level of Factor V and fibrinogen in obese and normal weight subjects.

Methods: This study was started on December 2015 and completed on June 2016, and included 51 obese attended alyarmouk Teaching Hospital. As well 25 non-obese subjects, were recruited as a control, age range  from18to 50 years old .The hemostatic parameters done for them included the prothrombin time, activated partial thromboplastin time, FV activity, fibrinogen level, and platelet count.

Results: There were insignificant difference in the means of prothrombine time (PT),activated partial thromboplastine time(aPTT), Factor V activity( FV)  and Platelet count (PLT)of obese group compared to control  group with P value (0.63, 0.902, 0.44, 0.484) respectively. There was significant difference in  the mean  of fibrinogen of obese group compared to control  group with P value (0.006).The correlation between BMI and (PT, PLT, FV and fibrinogen)in obese and control study groups were statistically  insignificant with (P > 0.05)  , but a significant positive correlation between BMI and PTT in obese group was found with  (P=0.037). There was a significant negative correlation between FV and PT in obese and control groups (P =0.001).There was insignificant positive correlation between fibrinogen and PT in obese and control groups (P > 0.05). 

Conclusions: Significant difference in the mean of plasma level of fibrinogen concentration between obese group and normal weight group was found. Insignificant difference in the means of PT, aPTT, platelet count and FV activity between obese group and normal weight group were found.

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Publication Date
Sun Oct 01 2017
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Measuring of Plasma Melatonin Level in Patients with Preeclampsia

Background: disturbed physiological rhythm of blood pressure in preeclampsia is a common finding. The role of oxidative stress in pathogenesis of preeclampsia is well accepted. Melatonin is a powerful free radical scavenger so it's rapidly consumed by enhanced reactive oxygen species in preeclampsia causing non-dipping in blood pressure.
Objective: To evaluate the change in plasma melatonin levels in patients with preeclampsia and its relationship with blood pressure.
Patients and methods: In this prospective case control study a total of 40 primigravidae pregnant women were recruited during the period of 11 months between August 2015 and August 2016 in Baghdad teaching hospital, medical city, Iraq, divided into two groups:
Firs

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Publication Date
Sun Sep 26 2021
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Vitamin D level and telogen hair loss: A Case control study

Abstract

 

Background: Hair loss is a common skin condition. Hair is not a vital organ but losing it has a worse effect on the psychological state of the patient and may interrupt his daily social activities. Telogen effluvium founded to be the commonest noninflammatory cause to diffuse hair loss. Since nutritional disturbances are one of the triggering factors for it. It might be useful in the management of TE Due to the limited number of studies& little information is available on this subject possible role of vitamin D or its deficiency should be studied further.

Aim of the study:  to determine the association between Telogen effl

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Publication Date
Sun Jan 02 2011
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Association of Fibrinogen as a Myocardial Infraction Risk Factor in Men

Background: Acute myocardial infarction (AMI) is an irreversible myocardial injury and necrosis caused by serious and long term ischemia. Fibrinogen is considered as
one of the probable risk factors of myocardial infarction.
Patients and methods: 1.8-mL venous blood specimen from 40 patients with MI and 50 control subjects was obtained and put it into tubes containing 0.2 mol/L trisodium citrate. Plasma fibrinogen level was determined by the method of Clauss (Diagnostic Stago, France).
Results The mean age of patients was (45.2 ± 6) years in patients with premature myocardial infarction and (45.06±5) years in the control group (p =0.07). There were no statistically significant relationships between the

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Publication Date
Sun Mar 01 2009
Journal Name
Baghdad Science Journal
The Relationship Between Hyperglycemia and the Rheumatoid Factor in the Serum of Diabetic Patients

This study was conducted to determine the relationship between two most common diseases in Iraqis patients , which are Diabetic mellitus (DM) and Rheumatoid Arthritis (RA); seeking rheumatoid factor in hyperglycemic sera. The results revealed that ; 62.5% of hyperglycemic (HG) patients had positive rheumatoid factor (RF) . No difference in number between both gender of HG patients (20 males and 20 females ) , RF reaction was nearly similar in males and females of HG patients ( 12 &13 respectively ) . Only 40% out of patient controls had positive RF . None of the apparently healthy subjects had positive RF .

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Publication Date
Sat Jun 30 2018
Journal Name
College Of Islamic Sciences
Location and level of ambition At the University of Sulaimaniyah

The study of the concept of the location of control and the level of ambition of important topics and represent a large area in the educational and psychological sciences, which gives importance to this study at the present time, is the complex and difficult conditions experienced by the Kurdish man, all age groups or social segments, and because of the changes It increases the rate of stress and hardship, which in turn raises the rate of psychological and physical disorder to prevent a healthy individual's compatibility, which has a fundamental impact on their personality, leading to a defect in some important organs of the personality.
   The research aimed to identify the location of control among students of the Uni

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Publication Date
Wed Jan 30 2013
Journal Name
Al-kindy College Medical Journal
Relationship between screen watching and overweight or obesity in a Sample of Iraqi adolescents

Background: Obesity represents a clear and
present danger to the health of children and
adolescents. Its prevalence among American
youth has doubled in the past 3 decades, and
there are now more overweight and obese
adults in the United States than adults of
normal weight.
Objectives of the study:
1- Finding whether screen watching among
adolescents has an effect on increasing
prevalence overweight and obesity.
2- The effect of other variables like physical
activity, eating in front of screen, eating under
stress on obesity and overweight among the
subjects sample.
Patients &Methods: During 3 months period a
cross sectional survey was conducted on 4
high schools at Baghdad with total

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Publication Date
Sat Jul 01 2023
Journal Name
Journal Of The Faculty Of Medicine Baghdad
The Relationship between Levels of Serum Vit. D and Kidney Function in Diabetic Nephropathy Iraqi Patient: The relationship between vitamin D and diabetes nephropathy

Background: According to several animal and human studies, Vitamin D appears to play a substantial role in the development of diabetic nephropathy, However, the possibility of vitamin D's Reno protective impact and influence on the reversal of already-existing renal damage remains speculative. Vitamin D deficiency and insufficiency are ubiquitous worldwide and have been linked to a variety of pathophysiological conditions, including diabetes, allergies, autoimmune illnesses, pregnancy difficulties, and, more recently, worse COVID-19 clinical outcomes. From a translational perspective, the goal of this review is to look into the potential function of vitamin D in the development of diabetic kidney diseases

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Publication Date
Wed Feb 20 2019
Journal Name
Political Sciences Journal
Federal and problematic relationship between the center and the region in Iraq

The US invasion of Iraq in 2003 unleashed the repressed national aspirations of the Kurdish people. After the colonial powers, especially Britain, failed to establish a homeland of scattered Kurds in Iraq, Turkey, Syria and Iran, Iraq's Kurds managed to establish a semi-independent state in the north of the country Which lasted decades against the central authority in Baghdad in protest against what they call the forced integration of Kurds in the Iraqi state, and to obtain more rights and privileges as partners in this country. The federal region in the Kurdistan region of Iraq has become a reality, and it is eager not to strengthen its authority in return for the authority of the central government, but to annex other areas inhabited b

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Publication Date
Wed Mar 29 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Evaluation of the Relation between Asthma, Obesity and Leptin Level in Iraqi Asthmatic Patients and the Main Risk Factors that are Associated with Leptin Level

This study tries to clear the correlation and association between asthma, obesity and leptin levels. Also it will work to indicate the main risk factors which play role in the elevation of leptin level within asthmatic patients.  This is a case control study conducted on (38) asthmatic patients and (20) healthy control who were closely similar by age, gender and BMI. The main statistical tests used were student t test, linear regression test and correlation test. Significance was set at P < 0.05. Sampling method used for this study was convenience sampling method.  The main results of this study show a significant association and positive correlation between age (old age  â‰¥ 40 ye

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Publication Date
Sun Feb 03 2019
Journal Name
Journal Of The College Of Education For Women
The Relationship between the age of the pregnant mother and the values hemoglobin blood and packed cell volume (PCV) in the Third Trimester for different age groups (descriptive study)

Pregnancy pose an additional burden on the body of the mother so as to meet their needs and the needs of the fetus and the body's need to iron increases excessively during pregnancy and iron is an essential element for the formation of hemoglobin blood Either hemoglobin is the key ingredient for red blood cells which carries oxygen to parts of the body, alas, most of the pregnant women begin their pregnancy inadequate stocks of iron in their bodies, which does not cover their need and requirement of the fetus, especially in the second and third trimesters of pregnancy When you reach the mother to the period in which they did not have the adequate amount of iron to produce hemoglobin become the mother was anemic So emerged the problem of

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