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A trial Of Immunisation Against Cutaneous Leishmaniasis
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Background: Cutaneous leishmaniasis is an endemic protozoal disease in Iraq. Recovery from the disease confers a solid and permanent immunity. Vaccination with a living inoculum of promastigotes isolated from culture reduce the incidence of disease.
Objective: To show the efficacy of different types of antigens for protection of Balb/c mice against cutaneous leishmaniasis.
Methods: Thirty Balb Ic mice were divided in to six groups, groups 1-4 were immunized with different types of antigens (heat killed, freezing-thawing, formalin fixed and ultrasonicated). Received June 2005 Group 5 was treated with freshly harvested viable promastigotes from liquid medium as positive Accepted Nov. 2005 control and group 6 was kept as negative control. Leishmanin test was used for estimation of hypersensitivity of skin. Results: Immunization with antigens preparation revealed that, the immunized mice became resistant to infection.
Conclusion: Immunization of mice against cutaneous leishmaniasis is possible by using different types of antigens. Key words: Immunisation, cutaneous leishmaniasis, mice.

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Publication Date
Mon Nov 27 2023
Journal Name
Korean Journal Of Orthodontics
Effectiveness of laser-engineered copper-nickel titanium versus superelastic nickel-titanium aligning archwires: A randomized clinical trial
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Publication Date
Sat Jun 15 2019
Journal Name
Journal Of Baghdad College Of Dentistry
The Efficiency Of Physics Forceps In Comparison To The Conventional Dental Extraction Forceps: A randomized Clinical Trial
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Background: Tooth extraction is one of the most commonly performed procedures in dentistry. It is usually a traumatic process often resulting in immediate destruction and loss of alveolar bone and surrounding soft tissues. Various instruments have been described to perform atraumatic extractions which can prevent damage to the paradental structures. The physics forceps is one of those innovations in dental extraction technologies that claim to provide an efficient means for atraumatic dental extractions. Materials and method: A randomized clinical trial was conducted to compare the physics forceps with the conventional forceps for the removal of 28 mandibular single rooted teeth under the following parameters: incidence of crown, root, b

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Publication Date
Tue Jan 01 2019
Journal Name
Indian Journal Of Public Health Research & Development
A 4-Day Plaque-Regrowth Anti-Plaque Effect of a Combination of Green Tea and Salvadora Persica L.: A Randomized Controlled Crossover Clinical Trial
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Publication Date
Tue Aug 25 2020
Journal Name
Journal Of Clinical Medicine
Self-Limiting versus Rotary Subjective Carious Tissue Removal: A Randomized Controlled Clinical Trial—2-Year Results
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Background: the aim of this study was to assess the 2-year pulp survival of deep carious lesions in teeth excavated using a self-limiting protocol in a single-blind randomized controlled clinical trial. Methods: At baseline, 101 teeth with deep carious lesions in 86 patients were excavated randomly using self-limiting or control protocols. Standardized clinical examination and periapical radiographs of teeth were performed after 1- and 2-year follow-ups (REC 14/LO/0880). Results: During the 2-year period of the study, 24 teeth failed (16 and 8 at T12 and T24, respectively). Final analysis shows that 39/63 (61.9%) of teeth were deemed successful (16/33 (48.4%) and 23/30 (76.6%) in the control and experimental groups, respectively wit

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Publication Date
Sun Apr 01 2007
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Doxycycline In Pityriasis Rosea: Placebo- Controlled Clinical Trial
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Background: Pityriasis rosea is an acute, self-limiting skin disease, probably of infective origin. Doxycycline is a broad-spectrum antibiotic, and most probably has an
immunomodulator and an anti-inflammatory effect.
Objective: To assess the efficacy of doxycycline in the treatment of pityriasis rosea in patients evaluated between January 2001 and May 2002.
Patients and methods: This was a placebo-controlled clinical trial. One hundred and twenty patients with pityriasis rosea were included in the study; all of them were above 12 years of
age. They had been divided into 2 groups, the treatment group consisted of 60 patients and received doxycycline capsule. 100,mg orally for 14 days and the placebo group

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Publication Date
Wed Aug 30 2023
Journal Name
Al-kindy College Medical Journal
Viable Strategies to Increase Clinical Trial Patient Diversity
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In the United States, the pharmaceutical industry is actively devising strategies to improve the diversity of clinical trial participants. These efforts stem from a plethora of evidence indicating that various ethnic groups respond differently to a given treatment. Thus, increasing the diversity of trial participants would not only provide more robust and representative trial data but also lead to safer and more effective therapies. Further diversifying trial participants appear straightforward, but it is a complex process requiring feedback from multiple stakeholders such as pharmaceutical sponsors, regulators, community leaders, and research sites. Therefore, the objective of this paper is to describe three viable strategies that can p

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Publication Date
Sun Jan 03 2010
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Cutaneous complications of insulin therapy in patients with Type1 diabetes mellitus
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Background: Common complications of subcutaneous insulin injection include lipoatrophy and lipohypertrophy which may lead to erratic absorption of the insulin with the potential for poor glycemic control and unpredictable hypoglycemia. Other cutaneous complications are local and systemic insulin allergy.
Patients and methods: The study included 150 patients with type1 diabetes mellitus attending thediabetic clinic of Children Welfare Teaching Hospital who were assessed for cutaneous
omplications of insulin therapy especially at the sites of the injections. Data collected evaluated using chi square and Pvalue.
Results: Out of 150 patients, the male to female ratio was 1:1.3, with mean age of 11.34 years

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Publication Date
Wed Apr 01 2009
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Chronic ulcerative Cutaneous Vasculitis of the legs Clinical and histopathological study
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Background: Cutaneous small vessel vasculitis characterized by necrosis and inflammation of upper dermal blood vessels. It presents with ulcers and systemic manifestations after extensive acute onset. Many patients have a form of cutaneous vasculitis that presents with chronic painful ulcerations & purpuras involving the ankles without systemic manifestations, with some similarity in clinical presentation to livedoid vasculopathy.
Patients and Methods: Thirteen patients were seen in the Department of Dermatology and Venereology, Baghdad Teaching Hospital, for a period extending from January 2004 to March 2005. They were evaluated clinically, histopathologically and other laboratory studies. In additio

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Publication Date
Wed Mar 10 2021
Journal Name
Baghdad Science Journal
Relationship of blood groups in humans and skin infection leishmaniasis
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I have studied the relationship between blood groups in humans and disease Cutaneous injury for the first time in Iraq study showed the presence of a significant statistical relationship between them leather Bmsoy in hospitals in Baghdad and its suburbs

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Publication Date
Sun Jul 29 2018
Journal Name
Iraqi Journal Of Science
Epidemiological and clinical study of leishmaniasis in Kirkuk city, Iraq
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leishmaniasis is a disease of global concern, Leishmania types and  distribution rates vary from country to another. For visceral leishmaniasis serum samples were examined by the kala-azar dipstick rapid test. Meanwhile smears were taken from lesions, air dried, fixed and Leishman stained then microscopically examined for amstigote stage in cutaneous leishmaniasis. From April 2014 to April 2015, 150 samples for cutaneous leishmaniasis (CL) and 108 serum sample for visceral leishmaniasis (VL) from in and out patients in Pediatric, Azadi Teaching and Kirkuk General Hospitals were examined. The incidence of visceral leishmaniasis was very low (2.7%) comparing to that in cutaneous leishmaniasis (64.6%). No significant differenc

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