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iqjmc-1500
A trial Of Immunisation Against Cutaneous Leishmaniasis
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Background: Cutaneous leishmaniasis is an endemic protozoal disease in Iraq. Recovery from the disease confers a solid and permanent immunity. Vaccination with a living inoculum of promastigotes isolated from culture reduce the incidence of disease.
Objective: To show the efficacy of different types of antigens for protection of Balb/c mice against cutaneous leishmaniasis.
Methods: Thirty Balb Ic mice were divided in to six groups, groups 1-4 were immunized with different types of antigens (heat killed, freezing-thawing, formalin fixed and ultrasonicated). Received June 2005 Group 5 was treated with freshly harvested viable promastigotes from liquid medium as positive Accepted Nov. 2005 control and group 6 was kept as negative control. Leishmanin test was used for estimation of hypersensitivity of skin. Results: Immunization with antigens preparation revealed that, the immunized mice became resistant to infection.
Conclusion: Immunization of mice against cutaneous leishmaniasis is possible by using different types of antigens. Key words: Immunisation, cutaneous leishmaniasis, mice.

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Publication Date
Sun Feb 21 2021
Journal Name
Iraqi Journal Of Science
The antimicrobial effects of alcoholic leaves extract of salvia officinalis against multidrug resistant pseudomonas aeruginosa
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Publication Date
Thu Mar 30 2023
Journal Name
Iraqi Journal Of Science
Efficacy of Amphotericine B Ddrug Against Promastigote and Axenic Amastigote of Leishmania Dononvani in Vitro
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Leishmania are protozoan parasites belonging to the family Trypanosomatidae that cause high morbidity and mortality levels with a wide spectrum of clinical syndrome. This study aimed to investigate the effect of liposomal amphotericine B (AmBisome) drug on promastigote and axenic amastigote stages of Leishmania donovani isolate (MHOM/IQ/2005/MRU15)in comparison with pentostam SbV drug. Different concentrations of AmBisome and SbV drugs were investigated against Leishmania donovani promastigote and axenic amastigote. The ICR50R values of SbV and AmBisome drugs on promastigote were10.12 mg/ml and 2.21μg/ml, respectively, while they were 0.77μg/ml for axenic amastigote for both drugs. The present study concluded that axenic amastigote was

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Publication Date
Sun Apr 30 2023
Journal Name
Iraqi Journal Of Science
Efficacy of Amphotericine B drug Against Promastigote and Axenic Amastigote of Leishmania tropica in Vitro
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Leishmania are protozoan parasites belonging to the family Trypanosomatidae that cause high morbidity and mortality levels with a wide spectrum of clinical syndrome. This study aimed to investigate the effect of liposomal amphotericin B (AmBisome) drug on promastigote and axenic amastigote stages of Leishmania tropica. From the 20 isolates of cutaneous leishmaniasis collected from patients attended to the AL-Karama Teaching Hospital in Baghdad during the period from October 2013 until February 2014, only three isolates successfully transformed to motile promastigote stage in the culture media. The most active one is included in this study. Different concentrations of liposomal amphotericin B (AmBisome) and pentostam Sb (V) drugs were inv

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Publication Date
Fri Feb 26 2021
Journal Name
Iraqi Journal Of Science
The Antimicrobial Effects of Alcoholic Leaves Extract of Salvia Officinalis Against Multidrug Resistant Pseudomonas Aeruginosa
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Two isolates of Pseudomonas aeruginosa were isolated from patients with Urinary Tract Infection (UTI). The aim of this study was to determine the antimicrobial effect of alcoholic leaves extract of Salvia officinalis on Multidrug resistant (MDR) P. aeruginosa. Using the well diffusion test, the alcoholic leaves extract at 100mg/ml and 200 mg /ml was shown to possess antimicrobial activity against the tested microorganism. The inhibition zones of S. officinalis at 200 mg/ml, and 100 mg/ml of the extract showed diameters of 23mm and 20mm, respectively. But the diameters of the inhibition zones caused by treatment with the antibiotics Ciprofloxacin, Ticarcillin + Clavulanic acid, and Cefotaxime w

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Publication Date
Tue Jun 11 2019
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
The Protective Effect of Ethanolic Extract of Mentha spicata Against Irinotecan-Induced Mucositis in mice
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Irinotecan induced-mucositis is an inflammatory event of intestine caused by an increase in concentration of active metabolite 7­ethyl­10-hydroxycamptothecin (SN­38) in the intestine. Irinotecan must first be converted by a carboxylesterase (CES) to the active metabolite (SN­38), which is subsequently glucuronidated by the hepatic enzyme to SN38G. The SN-38G is deconjugated in the intestine to SN-38 via ?-glucuronidase produced by the intestinal bacterial flora, which accounts for SN-38 delayed intestinal mucositis of irinotecan. To study the protective effect of mentha in irinotecan-induced mucositis, intestinal mucositis induced by I.P injection of irinotecan (75mg/Kg/day) for 4 days. Mentha ethanolic extract orally administered to

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Publication Date
Mon Apr 04 2016
Journal Name
Journal Of Entomology And Zoology Studies
Defensive behavior in lemon butterfly Papilio demoleus L.(Lepidoptera: Papilionidae) against predation
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Publication Date
Wed Oct 01 2014
Journal Name
Journal Of Physical Education
Limiting standards for some defending tests against shooting for basketball juniors players
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The changes that happen in training progress especially in skill side demands tests researchers found poorness for patterns to special tests in defending skills against shooting although applying these tests on other samples without considering the age , so the problem of research came controlling the tests of defense against shooting that serve juniors players and match the original society to serve the basketball game . The research sample chosen for juniors players for Baghdad clubs in season (2011-2012) the sample numbered (82) players represented (7) clubs that their percentage (82%) , after gaining the data processed statically and we reached to conclusion that : defending tests against shooting applied first time in Iraq in Iraq envi

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Publication Date
Sun Jun 01 2014
Journal Name
Baghdad Science Journal
Complete Blood Count and Cinnamic acid activity against Cytoxan in albino mice.
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The aim of study to evaluated cinnamic acid and its activity on complete blood count(RBC,WBC,HG,HCV,MCH,MCHC and Plat.)and removed the cytoxan damage which caused bone marrow failure and leukemia and other that due to linked the cytoxan in 7- nitrogen of guanine based of DNA that lead to dead cells. Two concentration from pure cinnamic acid (5.6, 2.8 mg ? mice weight) in first step to choice the perfect concentration in comparison with each negative control ,positive control of cytoxan and the comparison group represent vitamin C. The second step to understand cinnamic acid mechanism activity towards cytoxan by used pre- cytoxan and post – cytoxan in interaction with perfect concentration of cinnamic acid dose (2.8 mg ? mice we

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Publication Date
Mon Jun 17 2019
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Transfer Factors as an Immunenhancer Against Adenovirus in Experimental Infection in Chicken
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 A group of birds were passively immunized by a transfer factor extracted from lymphocytes sensitized to adenovirus and then they were challenged by the virulent virus (adenovirus isolated from hydropericardium infected birds). The results indicatede that the groups of birds that received the transfer factor or sensitized lymphocytes were protected from having any grossly pathological changes and having a high level of anti adenovirus antibodies.

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Publication Date
Mon May 22 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Effect of Plant Extract of Zingiber officinale and Antibiotic Against some Types of Bacteria Causing Diarrhea
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   The study was conducted to evaluate the antibacterial activity of water and alcoholic extracts (cold and hot) of plant Zingiber officinale against different types of bacteria includeing (Staphylococcus aureus ØŒ Staphylococcus epidermis ØŒ Escherichia coli ØŒ Pseudomonas aeruginosa
  ØŒProteus spp.and Klebsilla pneumoniae).  High effect of the hot (water and alcoholic) extracts of plant Zingiber officinale was on the different types of bacteria.          Investigation of presence of active compounds (Alkaloids, Glycoside, Tannins, Saponine and Resine) in this plant parts was carried out.        Sensitivity test of the isolate

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