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CMV infection among HIV / AIDS patients in Iraq

Background: The aim of the study was to determine the prevalence of CMV infection among HIV / AIDS patients in relation to disease progression, and to study the mortality during the period of the study.
Patients and Methods: The study included 155 HIV/AIDS patients (148 HIV- infected and seven AIDS patients) and 122 apparently "healthy" controls. CMV (IgG and 1gM) antibodies were determined by ELISA. The patients were followed up for a period of nine months, and retested frequently for development of active CMV infection.
Results: The prevalence of CMV (IgG) antibodies in the HIV/AIDS patients was 100%. A significant higher prevalence of CMV (IgM) among AIDS patients (42.9°/6) than among HIV infected patients (0.0%) and "healthy" controls (0.8%). No deaths were reported among asymptomatic HIV infected patients while the mortality among AIDS patients was (42.9%). Only one patient (7.7%) out of 13 asymptomatic HIV infected developed active CMV infection 10 years later by testing for CMV (IgM) in 1991 and 2001.
Conclusion: Demonstration of active CMV is of prognostic value in detection of development of AIDS and survival of patients.

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Publication Date
Tue Mar 14 2023
Journal Name
Iraqi Journal Of Science
Frequency of CMV- Infection among Hemodialysis Patients in Tikrit City

It has been well documented that hemodialysis patients have impaired immune response, which may result in higher prevalence rates of viral infections, including CMV. Infections in these patients may be due to primary infection or, more commonly, by reactivation of latent virus or re-infection with exogenous virus, which may be introduced by blood transfusion. The aim of this study was to evaluate the frequency of CMV-IgG and IgM antibodies among hemodialysis patients. The current research included 116 hemodialysis patients (69 male and 47 female) who attended to Tikrit Teaching Hospital for the period from beginning of October/2013 to the end of April/2014. CMV-IgG was found in 102 out of 116 (87.9%), while CMV- IgM was detected in 10 ou

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Publication Date
Mon May 01 2006
Journal Name
East Mediterr Health J
Prevalence of HCV/HIV co-infection among haemophilia patients in Baghdad

Abstract To estimate the seroprevalence of HCV infection among HIV-infected haemophiliacs and to demonstrate the most prevalent HCV genotype, 47 HIV-infected haemophilia patients were screened for anti-HCV antibodies. By performing polymerase chain reaction and DNA enzyme immunoassay, HCV-RNA was detected with subsequent genotyping. Seroprevalence of anti-HCV antibodies was 66.0%. Of 31 HCV/HIV co-infected patients, 21 (67.7%) had no history of blood transfusion. We detected 4 HCV genotypes: 1a, 1b, 4 and 4 mixed with 3a, HCV-1b being the most frequent. Contaminated factor VIII (clotting factor) could be responsible for disease acquisition.

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Publication Date
Wed Jul 01 2009
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Knowledge of Secondary School Students on HIV/AIDS in Kirkuk Province / Iraq.

Background: The acquired immunodeficiency syndrome (AIDS) is a disorders caused by cellular and humoral immune dysfunction from infection by the human immunodeficiency virus (HIV 1 and HIV 2).
Patients and Methods: The study was carried out in Kirkuk governorate on 5090 secondary school students from different localities of the city, for the period from the beginning of October 2005 to the end of March 2006. A special questionnaire was applied for each student containing age, sex, class, parent’s education, mode of transmission & methods of prevention.
Results: There was no significant difference between male and female regarding the etiology of AIDS.The knowledge of secondary school students was

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Publication Date
Sun Apr 30 2023
Journal Name
Iraqi Journal Of Science
The Correlation between CMV Infection and Hypertension in Iraqi Patients

In order to study the correlation between CMV infection and increase in blood pressure among Iraqi patients, 201 blood samples were collected including; 88 male, 113 female hypertensive patients and 40 control samples. Patients sera were grouped into patients who are under medication (T), and patients who do not take any treat-ment for hypertension(NT). Samples were tested for CMV-IgM/IgG by ELISA, ren-in enzyme and interleukin-6(IL-6) levels were determined by ELISA too. The opti-cal density readings difference for CMV-IgG were significant between (T) and (NT) groups as well as when each group compared to control, level of renin enzyme showed significant difference between patients group(T and NT) and between each group compared to the

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Publication Date
Thu May 05 2022
Journal Name
Al-kindy College Medical Journal
Prevalence of Cytomegalovirus Infection among Suspected Infants in Baghdad: Prevalence of CMV Infection

Background: Cytomegalovirus (CMV) virus is a recognized important cause of congenital CMV infection which carries a significant risk for symptomatic disease and developmental defects in newborns. Its prevalence varies from place to other and time to time. This study is conducted to estimate its prevalence in Baghdad among infants suspected of having a congenital infection and to study the associated findings.   

 Subjects and Methods: The study was carried out in Al-Alwyia pediatrics teaching hospital. Data were collected, and blood samples were taken for infants suspected to have intrauterine infections over a period of one year, from 1 October 2019 to 1 October 2020.  Immunoglobulin M (IgM) tests for CMV w

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Publication Date
Thu May 28 2020
Journal Name
Iraqi Journal Of Science
Dynamical Analysis Within-Host and Between-Host for HIV\AIDS with the Application of Optimal Control Strategy: Dynamical analysis within-host and between-host for an HIV\AIDS

The aims of this paper is investigating the spread of AIDS both within-host, through the contact between healthy cells with free virus inside the body, and between-host, through sexual contact among individuals and external sources of infectious. The outbreak of AIDS is described by a mathematical model consisting of two stages. The first stage describes the within-host spread of AIDS and is represented by the first three equations. While the second stage describes the between-host spread of AIDS and represented by the last four equations. The existence, uniqueness and boundedness of the solution of the model are discussed and all possible equilibrium points are determined. The local asymptotic stability (LAS) of the model is studied, wh

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Publication Date
Mon Apr 01 2019
Journal Name
Biochemical And Cellular Archives
Prevalence of Hbv, Hcv and Hiv-1, 2 infections among patients in Saladin governorate, Iraq

Hepatitis B and Hepatitis C viruses are the major health problem in the worldwide. In the Middle East, the prevalence of HBV in general population with the chronic infectionsis 2-5%,whereas the prevalence of HCV is about 1% in Arabian Gulf countries. World Health Organization (WHO) revealed that the risks of HBV and HCV transmissionas well as human immunodeficiency virus (HIV) through the transfusion of contaminated blood and blood products is high, because of the fragility of health services in these countries. Several viral diseases are transportby different modes like bloodtransfusion, sexual contact, and unsafe injections. The mostcommon blood-transmitted viruses are hepatitis B virus(HBV), hepatitis C virus (HCV) and humanimmunodeficie

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Publication Date
Sun May 15 2022
Journal Name
Al-kindy College Medical Journal
A serology conundrum – HIV infection in acute babesiosis infection could merely be a false positive result

Babesiosis is a tick-borne disease caused by Babesia microti. We present a case of false positive HIV in the setting of confirmed babesiosis infection. An understanding that patients with babesiosis can have a false positive HIV test result is important in management decisions.

 

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Publication Date
Fri Mar 01 2019
Journal Name
Research Journal Of Biotechnology
Etiopathogenesis of CMV in rheumatoid arthritis patients

Rheumatoid arthritis (RA) is one of the autoimmune diseases characterized by the synovial inflammation which causes organs and tissues damage especially synovial tissues and joints. The study included 50 serum samples from patients with rheumatoid arthritis (RA) when compared with 50 serum samples from healthy individuals as control with age range 35 – 60 years (41.3 ± 2.4 years vs. 41.0 ± 2.0 years, respectively). ELISA technique was used to assess the Anti-cyclic citrullinated peptide IgG antibody (anti-CCP IgG Ab) level, anti-rheumatoid factor IgG antibody (anti-RF IgG) and anti-Cytomegalovirus (anti-CMV IgG) antibodies frequencies in the studied groups. The present findings demonstrated that all RA patients have 100% seropositive fr

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Publication Date
Fri Jul 01 2022
Journal Name
Iraqi Journal Of Science
A comparison between Trichomoniasis Infection and other Vaginal Infection among Females in Baghdad Governorate- Iraq

Trichomoniasis is a parasitic disease caused by the protozoan Trichomonas vaginalis. It is the most common sexually transmitted protozoal infection. There is no estimated of infection intensity among reproductive-age females. Further studies of the infection intensity of trichomoniasis and other vaginal infection will highlight the importance of this pathogen as a public health problem. A total of 614 females from Baghdad city were screened for T. vaginalis from March 2015 to September 2015. Females aged 13–61 years old provided vaginal swab specimens. The vaginal fluids extracted from these swabs were checked for the presence of T. vaginalis and other vaginal infection using microscopic examination. Overall, 525 (85.5%) of 614 was scr

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