Background: Reports denote that changes in day length enhance or suppress components of immune function in several mammalian species. The aim of present experimental study is
directed to test the hypothesis deals with the effect of photoperiods on some immune limbs responsiveness.
Materials and Methods: Twenty six male and female BALB/C mice, 5-7 weeks old, 14- 18gm weight divided into two groups, test groups (n.=8 mice for each sex) and control
groups (n.=5 for each sex). Test groups were kept in a dark room for a month, while control groups were kept in a room where the photoperiod was day light: darkness 12:12hr. All
studied groups immunized with o.2ml (10% sheep red blood cells) on day 4 and 8 of the last 12 days of the experiment. The weight of all animals were measured at the beginning and the
end of the experiment. Arthus reaction, delayed type hypersensitivity and serum antibody titer were assessed on day 11 and 12 of program.
Results: Significant increased (P<0.005) in body weight, index level of Arthus reaction, delayed type hypersensitivity and serum antibody titer in the test groups in comparison with
the control groups.
Conclusion: Data are consistent with the hypothesis that immune parameters are enhanced in short photoperiods or continuous darkness
Infection with cryptosporidiosis endangers the lives of many people with immunodeficiency, especially HIV patients. Nitazoxanide is one of the main therapeutic drugs used to treat cryptosporidiosis. However, it is poorly soluble in water, which restricts its usefulness and efficacy in immunocompromised patients. Surfactants have an amphiphilic character which indicates their ability to improve the water solubility of the hydrophobic drugs. Our research concerns the synthesis of new cationic Gemini surfactants that have the ability to improve the solubility of the drug Nanazoxide. So, we synthesized cationic Gemini surfactants. N1,N1,N3,N3-tetramethyl-N1,N3-bis(2-octadecanamidoethyl)propane-1,3-diaminium bromide (CGSPS18) and 2,2‘-(etha
... Show MoreNowadays laser in medicine is a rapidly growing field in both researches and applications and many studies have been done in bacteriology against different types of lasers. The effect of the laser depends on many factors, one of the laser factors was the wavelength. The red wavelength band has been considered as a stimulated wavelength for prokaryotic and eukaryotic cells. In this study, three clinical species of Gram-negative bacteria (E. coli, Proteus mirabilis, and Pseudomonas aeruginosa) were exposed to 650 nm band of red region wavelength by a diode laser. The effect of that wavelength appeared on the growth curves for each species along 3 days after laser treatment. The energy density (E.D.) 2.8 J/cm2 gave a positive effect on grow
... Show MoreThe result showed that hot water and ethanol extracts of Nigella sativa contain alkaloids ,saponins, flavonoids,tannins,glycosides,terpins and steroids. Albino mice were administered orally with 0.1 of the extract at dose of 100 mg/kg, body weight the results showed high level of white blood cell ,total and differential count of WBC,phagocytosis index, mitotic index, Arthus and delayed type hypersensitivity. The result, also showed high level of hemoglobin (Hb) and the packed cell volume (PCV) the alcoholic extract has been found more efficient than hot water extract on mice.
The rapid change in economic is a serious challenge facing all countries around the world, even developed ones. This challenge is increasing as the world enters the age of knowledge in which different knowledge and technologies have emerged and the distance between the emergence of scientific knowledge and its actual application on the ground has been reduced as well as the growing role of science and technology in community development. One of the most important technology amongst these technologies is nanotechnology, where this technology plays a major role in the development of products and modern devices and reduces cost with quality improvement. This technology is cross-cultural, requires a comprehensive knowledge structure and depe
... Show MoreAn extraction-spectrophotometric technique has been applied and approved for the estimation of orphenadrine citrate in the presence of paracetamol in a binary synthetic mixture and in combined drugs. The procedure is built on the formation of a soluble red colour orphenadrine citrate – eriochrom black T (EBT) ion pair complex at pH 1.40, while the paractamol not paired. The produced red colour ion-pair complex was extracted with chloroform and showed maximum absorption at 509 nm. For quantitative evaluation Beer’s law applied to plot the absorbance against concentration, the relation was a linear in the concentration range of 0.10-6.00 µg/ mL with the molar absorptivity 4.4025 x104 L / mol. cm. The limit of detection and
... Show MoreIn this research, we did this qualitative and quantitative study in order to improve the assay of aspirin colorimetrically using visible spectrophotometer. This method depends on aqueous hydrolysis of aspirin and then treating it with the ferric chloride acidic solution to give violet colored complex with salicylic acid, as a result of aspirin hydrolysis, which has a maximum absorption at 530nm. This procedure was applied to determine the purity of aspirin powder and tablet. The results were approximately comparative so that the linearity was observed in the high value of both correlation coefficient (R= 0.998) and Determination Coefficient or Linearity (R2= 0.996) while the molar absorpitivity was 1.3× 103 mole
In the current research, the work concentrated on studying the effect of curvature of solar parabolic trough solar collector on wind loading coefficients and dynamic response of solar collector. The response of collector to the aerodynamic loading was estimated numerically and experimentally. The curvature of most public parabolic trough solar collectors was investigated and compared. The dynamic response of solar collector due to wind loading was investigated by using numerical solution of fluid-structure interaction concept. The experimental work was done to verify the numerical results and shows good agreement with numerical results. The numerical results were obtained by using finite element software package (ANSYS 14). It was found
... Show More