Background: Nephrotic syndrome in children is a clinical manifestation of different histopathological subtypes.
Objectives: The objectives were to study the different histopathological subtypes of idiopathic nephrotic syndrome and to study their clinical and biochemical parameters at the time of diagnosis for children admitted to Children Welfare Teaching Hospital.
Methods: A Retrospective study M’as done on 160 children with idiopathic nephrotic syndrome who were diagnosed and/or treated at Children Welfare Teaching Hospital and were followed up in the pediatric nephrology consultation clinic betM'een April 2004 and April 2006.
Results: The study group included 40 children with idiopathic nephrotic syndrome r Who underwent renal biopsy. There were 26(68.7%) males and 14(31.2%) females.
Age at onset ranged between (1-15) years, median age (3.5) years. Facial oedema M’as fcnmd in 90%, hypertension in 45% patients, gross hematuria in 27.5 and persistent microhematuria in 45%. Sixteen (40%) patients had focal and segmental glomemlosclerosis on renal biopsy, nine (22.5%) patients minimal change nephrotic syndrome, eight (20%) patients mesangioproliferative glomerulonephritis, and seven (17.5%) patients had membranoproliferative glomerulonephritis.
Conclusion: Focal and segmental glomemlosclerosis was the most common histopathological subtype in our study group. Further large studies is needed to find out changing trends of histopathology in childhood nephrotic syndrome
The coronavirus-pandemic has a major impact on women's-mental and physical-health. Polycystic-ovary-syndrome (PCOS) has a high-predisposition to many cardiometabolic-risk factors that increase susceptibility to severe complications of COVID-19 and also exhibit an increased likelihood of subfertility. The study includes the extent of the effect of COVID-19-virus on renin-levels, glutathione-s-transferase-activity and other biochemical parameters in PCOS-women. The study included 120 samples of ladies that involved: 80 PCOS-patients, and 40 healthy-ladies. Both main groups were divided into subgroups based on COVID-19 infected or not. Blood-samples were collected from PCOS-patients in Kamal-Al-Samara Hospital, at the period between Decembe
... Show MoreThe study aimed to evaluate Glucagon-Like Peptide-1 levels in Polycystic ovary syndrome (PCOS) infertile female with Diabetes Mellitus (DM) and compare the results with control group, also, to find the correlation for GLP-1 with Luteinizing hormone (LH), Follicle stimulating hormone (FSH) and LH/FSH ratio that may be used in prediction atherosclerosis in these patients. The study included nineteen women with age ranged (30-40) years and BMI ranged between (30-35) Kg/m 2. Subjects were divided into two groups: group (1) consist of (45) females as a healthy control and group (2) consist of (45) infertile females with PCOS and DM as complication. Fasting serum glucose was determined by using commercial kits (Biolabo SA-France); LH, FSH, prolac
... Show MoreThe article examines metaphors as one of the fundamental means used by D. Rubina when writing the novel “Parsley Syndrome” to form images of dolls as equal heroes of the work. The author of the article continues research related to the work of Dina Ilinichna Rubina, a representative of modern Russian prose.
Acute respiratory distress syndrome (ARDS) is defined as a type of respiratory failure that is caused by a variety of insults such as pneumonia, sepsis, trauma and certain viral infections. In this study, we investigated the effect of an endocannabinoid, anandamide (AEA), on ARDS induced in the mouse by
Background: Polycystic ovary syndrome is a heterogeneous disorder and its etiology appears to be complex and multifactorial; characterized by hyperandrogenism, chronic anovulation and infertility. It’s associated with evidence of low-grade chronic inflammation, as indicated by the presence of elevated levels of high sensitive C- reactive protein levels, interleukin-6 and tumor necrosis factor-α. The source of excess circulating tumor necrosis factor-α in obese Polycystic ovary syndrome patient is likely to be the adipose tissues while in lean women increased visceral adiposity has been proposed as a source of excess tumor necrosis factor-α.Objectives: to evaluate the levels of high sensitive C- reactive protein, tumor necrosis facto
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