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A Study Of Angiogenesis In Human Colorectal Tumors By Using Anti-Cd34 Antibody. (Assessment By Light Microscope And Computer–Aided Image Analysis System)

Background:
Angiogenesis plays a crucial role in tumorigensis; several reports have described a significant increase in microvessel density (MVD) in colorectal carcinogenesis There are
several methods to measure the angiogenesis in neoplasms, but immunohitochemistry seems to be the mainstay of all. This method enable us to measure the tumor microvessel densities highlighted by using antibodies directed against endothelial cell markers like CD31,CD34 or others; then assessment of MVD by manual count of the number of microvessels in what appears to be the most vascular area of the tumor(called the hot spot) using a protocol described by Weidner et al.Automated cellular imaging system is used to analyze
immunohistochemically stained slides .studies have shown that the device offers accurate precision and reproducibility of immunostained slide analysis exceeding that possible with
manual evaluation which was the prevalent method.
Aims of the study:
To assess the angiogenesis in normal, adenomatous (benign) and malignant colorectal tissues using CD34 and the microvessels will be measured both manually by hot spot
method as the MVD and by the use of computerized image analysis system as fraction area ,we correlate between microvessels density and fraction area with various
clinicopathological parameters in colorectal cancer (CRC), and to a compare between the results which obtained from both methods.
Methods:
Paraffin embedded archival materials from 50 cases including three normal resection (non tumoruos) margins, 12 benign colonic lesions and 35 colonic adenocarcinoma were
used . 5mm section were cut and they were stained by anti CD34 antibody Angiogenesis was measured as MVD by two methods : manually by light microscope and by a computer
image analysis system (as fraction area). Then the MVD and fraction area were correlated with different clinicopathological parameters.
Results :
This study demonstrate that there is a statistical difference in MVD and fraction area in both hot spot method and CIAS respectively between benign and malignant tumors . P value
< 0.05 in hot spot method and less than 0.001 in CIAS and there was highly significant correlation between MVD and fraction area with the grade . There was significant increase
in MVD and fraction area from well differentiated to moderately differentiated and to poorly differentiated .There was no significant correlation between MVD and lymph node
involvement by hot spot method but CIAS proved a significant correlation between fraction area and lymph node involvement.Both methods (hot spot and CIAS) proved no
significant correlation with age , sex , size of the tumor , site of the tumor , stage of the tumor and the number of lymph node involverment.

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Publication Date
Sun Jan 01 2023
Journal Name
Aip Conference Proceedings
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Publication Date
Sun Jun 01 2014
Journal Name
Baghdad Science Journal
Building a Reliable Steganography System Using Random Key in a spatial Domain of Image

With time progress importance of hiding information become more and more and all steganography applications is like computer games between hiding and extracting data, or like thieves and police men always thieve hides from police men in different ways to keep him out of prison. The sender always hides information in new way in order not to be understood by the attackers and only the authorized receiver can open the hiding message. This paper explores our proposed random method in detail, how chooses locations of pixel in randomly , how to choose a random bit to hide information in the chosen pixel, how it different from other approaches, how applying information hiding criteria on the proposed project, and attempts to test out in code, and

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Publication Date
Wed Jun 28 2023
Journal Name
Engineering Applications Of Computational Fluid Mechanics
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Publication Date
Sun Jun 04 2017
Journal Name
Baghdad Science Journal
Human Computer Interface for Wheelchair Movement

This paper aims to develop a technique for helping disabled people elderly with physical disability, such as those who are unable to move hands and cannot speak howover, by using a computer vision; real time video and interaction between human and computer where these combinations provide a promising solution to assist the disabled people. The main objective of the work is to design a project as a wheelchair which contains two wheel drives. This project is based on real time video for detecting and tracking human face. The proposed design is multi speed based on pulse width modulation(PWM), technique. This project is a fast response to detect and track face direction with four operations movement (left, right, forward and stop). These opera

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Publication Date
Thu Sep 01 2022
Journal Name
Civil Engineering And Architecture
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Publication Date
Thu Sep 09 2021
Journal Name
Turkish Journal Of Physiotherapy And Rehabilitation,
The Violation of Religious Human Rights: A sample Analysis of an Offensive Image of Islamic Concept

The purpose of this paper is to investigate Religious Human Rights Violations. Religious liberty is essential for everyone, everywhere. Because religion is significant to everyone, everywhere. Humans are religious by nature. Our nature drives us to seek answers to deep questions about ultimate things. We cannot live a fully human life unless we are free to seek those answers and live according to the truths we discover. In this study, the researcher used Marsh and White model for analysis A sample of an offensive image of an Islamic concept from the book "Mohammad believes it or else." this book is a comic book written by pseudonym Abdullah Aziz and published by Crescent Moon Publishing company. The book is marked with anti- Mohammad, preju

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Publication Date
Wed Mar 18 2020
Journal Name
Baghdad Science Journal
On Light Mapping and Certain Concepts by Using m_X N-Open Sets

The aim of this paper is to present a weak form of -light functions by using -open set which is -light function, and to offer new concepts of disconnected spaces and totally disconnected spaces. The relation between them have been studied. Also, a new form of -totally disconnected and inversely -totally disconnected function have been defined, some examples and facts was submitted.

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Publication Date
Sun Sep 06 2015
Journal Name
Baghdad Science Journal
A study of the effect of new cobalt (II) complex and cyclophosphamide drug on (GPT, ALP) activity by using in vivo system

The present work involved a study the effect of cobalt(II) complex with formula [CoL(H2O)NO3] .4ETOH where L=Nitro [5-(P-nitro phenyl) -4-phenyl-1,2,4 traizole-3-dithiocarbamato hydrazide] aqua. (4) Ethanol and anti-cancer drug - cyclophosphamide on specific activity of two liver enzymes (GPT,ALP) by utilizing an in vivo system in female mice. On the enzymatic level an inhibition in the activity of GPT was noticed in different body organs such as liver, kidney and lung. The inhibition was noticed in both test and cyclophosphamide drug (cp). Mice were treated with three doses of cyclophosphamide (90,180, 250) ?g/ mouse for three days. The same doses were used for the cobalt (II) complex. The liver shows the highest rate of(GPT) inhibition co

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Publication Date
Mon Mar 01 2010
Journal Name
Basrah Journal Of Science
Publication Date
Wed Jan 12 2022
Journal Name
Iraqi Journal Of Science
Classification of Iraqi Anber Rice by Using Image Processing and KNN Algorithm

Image classification takes a large area in computer vision in term of quality or type or data sharing and so on Iraqi Anber Rice in they need this kind of work, where few in the field of computer science that deal with the types of Iraqi Anber rice, and because of the Anber Rice are grown and produced in Iraq only, and because of the importance of rice around the world and especially in Iraq. In this paper a proposed system distinguishes between the classes of Iraqi Anber Rice that Grown in different parts of Iraq, and have their own specifications for each class by using moment invariant and KNN algorithm. Iraqi Anber Rice that is more than Fiftieth class Cultivated and irrigated in different parts of Iraq, and because of the different

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