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Role of Chloroquine phosphate on Acute phase reactant in patients with knee osteoarthritis
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Background: The acute phase response is a major pathophysiologic phenomena that accompanies inflammation whether acute or chronic. The complements 3 (C3), complement4
(C4) and C-reactive protein (CRP) are positive acute phase proteins (+ve APPs) their production is increased by hepatocyte in osteoarthritis (OA). Chloroquine (CQ) which is a diprotic weak base traditionally used to treat malaria.Todate, the phosphate salt of CQ is used to decrease +ve APPs.
Objective: To evaluate the role of chloroquine phosphate on acute phase proteins C3, C4 and Creactive protein in patients with knee OA.
Subjects and methods :A total of seventy four patients (45 female and 29male) were selected randomly from the outpatients clinic in Baghdad teaching Hospital, Medical City, Baghdad
suffering from knee OA were treated with oral dosage form of CQP for one month, twice daily. The levels of C3, C4 and C-reactive protein in serum of all patients were measured before and after treatment using ELISA technique.The serum level of C3, C4 and C-RP were calculated as mean ± standard error of mean (SEM); paired t-test was used; S= significant, P value < 0.05
Results :The levels of C3, C4 and C-RP were significantly reduced (P< 0.05) in serum of all patients after treatment with CQP for one month.
Conclusion :CQP is a disease modifying anti rheumatic drug (DMARD) used for patients suffering from KOA in order to reduce their C3, C4 and C-RP value and improves the disease
status.

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Publication Date
Sun Jul 02 2006
Journal Name
Journal Of The Faculty Of Medicine Baghdad
acute renal fail ure in rasheed unit
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background:

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Publication Date
Thu Nov 14 2019
Journal Name
Al-kindy College Medical Journal
Role Iron in Diabetes mellitus type 2 of the patients in province Diwaniya
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Background: Diabetes mellitus is a common health problem of the world. Iron may be a part of the cause of the disease and its Complications

Objectives: This study was designed to determine the relationship between the levels of iron indices  and diabetes mellitus type 2. Type 2

Type of the study: Cross –sectional study.

Methods: diabetes mellitus is clinical condition characterized by hyperglycemia due to the absolute or relative deficiency of insulin. It is also followed by pathological abnormalities like impaired insulin secretion, peripheral insulin resistance, and excessive hepatic glucose production. Although type 2 diabetes mellitus i

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Publication Date
Wed Dec 30 2020
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
The Role of Clinical Pharmacist in Reducing Drug Related Problems in Hemodialysis Patients
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Abstract

Prescribing drugs to patients to treat ailments or reducing their morbidity may not be enough, even if the drugs were all indicated and in the right dose. Clinical pharmacists play a pivotal role in conducting information and instruction to patients and conveying feedback to treating physician when appropriate, and the final goal is in the interest of the patient.  Identification and classification of drug related problems and discussing them with the health care providers.  Prospective, interventional, clinical study for 180 hemodialysis patients, and was designed as two phases, an observational phase to identify drug related problems and classifying them according to the latest Pharmaceutical

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Publication Date
Sun Jul 03 2005
Journal Name
Journal Of The Faculty Of Medicine Baghdad
PREGNANCY RATE AFTER OVULATION INDUCTION, SPERM INTRAUTERINE TRANSFER (SIUT) AND LUTEAL SUPPORT THERAPY IN LUTEAL PHASE DEFECT (LPD) INFERTILE PATIENTS.
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Summary:
Background: It is well known that the early removal of corpus luteum (CL) in pregnant women results in abortion . Defects in the function of CL lead to deficiency in the secretion of progesterone which adversely affect human embryo implantation .
Aim of the work: l)to determine progesterone concentration in the luteal phase defect (LPD) patients complaining from infertility and 2) to evaluate the clinical value of ovulation induction, sperm intrauterine insemination SIUT and luteal support therapy in the treatment of LPD patients.
Patients & Methods: One hundred and twelve LPD patients were involved in this study. The progesterone concentrations were performed by radioimmunoassay method on cycle day 21. Patients wer

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Publication Date
Sun Oct 01 2006
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Bone Marrow Reticulin Content In Acute Leukemia
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Background: Increase in marrow reticulin has long been recognized in primary myelofibrosis, but little was known about the reticulin structure of leukemic marrows, there has been a tendency to accept an increase in marrow reticulin as evidence of myelofibrosis. Similarly, there has been a tendency to diagnose as "acute myelofibrosis" cases of acute leukemia with brisk reticulin and early collagen production. This study was undertaken to determine incidence, type and pattern of fibrosis in the bone marrow of patients with acute leukemia, both acute lymphoblastic and acute myeloid leukemia.
Method: thirty-five bone marrow biopsy specimens from patients with acute leukemia were examined histologically; connective tissue stains were appli

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Publication Date
Thu Mar 30 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Comparative Evaluation of Using Intranasal Desmopressin, Parenteral Diclofenac or their Combination in the Management of Acute Renal Colic Pain in Iraqi Patients
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         There is a suggestion that an antidiuretic hormone-induced decrease in diuresis might contribute to the rapid relief of the acute pain in renal colic. This study was designed to evaluate the efficacy of desmopressin nasal spray compared with diclofenac given intramuscularly in patients with acute renal colic. The study included 75 patients randomized into three different groups; group A received desmopressin (40 μg, nasal spray), group B diclofenac (75 mg) intramuscularly and group C, both desmopressin and diclofenac. Pain was assessed using a visual analogue scale (a 10-cm horizontal scale ranging from `no pain' to `unbearable pain') at baseline, 10, 20 and 30 min after administering t

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Publication Date
Wed Oct 01 2014
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Assessment of Serum Interleukin-2, -4 and C-reactive protein Levels in patients with Giardiasis and Cryptosporidiosis
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Background: Giardia lamblia and Cryptosporidium parvum are recognized as important health problem in different countries. Humans may infect by two parasites at different age groups. But more common in countries with poor sanitation and unsafe water.  Cellular and humoral response is engaged by the host to fight against parasitic infection, cytokines are produced by CD4 of payer's patches or generated from the mucosa lymphoid tissue as result of long duration antigen stimulation via trophozoites or cyst stage or others.    

Objectives: To evaluate the levels of IL-2, -4 and C- reactive protein in the sera of patients with     &nbsp

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Publication Date
Tue Jul 01 2008
Journal Name
Journal Of The Faculty Of Medicine Baghdad
The role of Bcl-2 protein, Bax protein and there ratio in peripheral blood lymphocytes of asthmatic patients
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Background: Asthma is an inflammatory airway disease; this inflammatory response can be attributed to reduced lymphocyte apoptosis in peripheral blood and in airway tissues.
The mechanism behind this could be attributed to decreased Bcl2 protein and increase Bax protein in peripheral blood lymphocytes of asthmatic patients.
Aim: to explore the mechanism behind decreased lymphocyte apoptosis in peripheral blood of asthmatic patients at cellular level.
Method: Ninety four subjects; (44) control and (50) patients were included in this study during the period from (2003) to (2004). The aspirated lymphocytes for each individual
were prepared and stained by immunocytochemistry to study the percentage of antiapop

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Publication Date
Sun Sep 30 2001
Journal Name
Iraqi Journal Of Chemical And Petroleum Engineering
Two Phase Flow in Large Diameter Pipe
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Publication Date
Fri Dec 14 2018
Journal Name
Journal Of Legal Sciences
Procedural support In the initial investigation phase
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يعد الإسناد الإجرائي من الركائز الأساسية في الإجراءات  الجنائية وعلى الرغم من ذلك بلم تكن هناك دراسات واسعة ، اذ عد الفقه والقضاء هذا الموضوع من الشكليات المسلم بها في الإجراءات  الجنائية فانه لم تتضمن غالبية التشريعات الإجرائية الجنائية النص صراحة على تعريف الإسناد الإجرائي وترك ذلك للفقه ، فالمشرع العراقي لم يحدد مفهوم الإسناد الإجرائي في قانون اصول المحاكمات الجزائية رقم (23) لسنة 1971 المعدل وكذلك في

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