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Role of Chloroquine phosphate on Acute phase reactant in patients with knee osteoarthritis
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Background: The acute phase response is a major pathophysiologic phenomena that accompanies inflammation whether acute or chronic. The complements 3 (C3), complement4
(C4) and C-reactive protein (CRP) are positive acute phase proteins (+ve APPs) their production is increased by hepatocyte in osteoarthritis (OA). Chloroquine (CQ) which is a diprotic weak base traditionally used to treat malaria.Todate, the phosphate salt of CQ is used to decrease +ve APPs.
Objective: To evaluate the role of chloroquine phosphate on acute phase proteins C3, C4 and Creactive protein in patients with knee OA.
Subjects and methods :A total of seventy four patients (45 female and 29male) were selected randomly from the outpatients clinic in Baghdad teaching Hospital, Medical City, Baghdad
suffering from knee OA were treated with oral dosage form of CQP for one month, twice daily. The levels of C3, C4 and C-reactive protein in serum of all patients were measured before and after treatment using ELISA technique.The serum level of C3, C4 and C-RP were calculated as mean ± standard error of mean (SEM); paired t-test was used; S= significant, P value < 0.05
Results :The levels of C3, C4 and C-RP were significantly reduced (P< 0.05) in serum of all patients after treatment with CQP for one month.
Conclusion :CQP is a disease modifying anti rheumatic drug (DMARD) used for patients suffering from KOA in order to reduce their C3, C4 and C-RP value and improves the disease
status.

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Publication Date
Tue Jul 01 2008
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Viral hepatitis markers screen in children with Acute Lymphoblastic Leukemia Experience of Children Welfare Teaching Hospital
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Background:
Patients treated for pediatric malignancy are at high risk of parenterally transmitted viral hepatitis.
Objectives:
To detect the seroprevalence of hepatitis B and C viral infections in children with Acute Lymphoblastic Leukemia & identify some variables that could affect its
prevalence in these patients.
Patients and Methods:
One hundred fifty pediatric acute lymphoblastic leukemia patients, presented to Children Welfare Teaching Hospital, Baghdad, during the period from March 11th
2007 to July 31st 2007 were enrolled in this study; they were 103 males, 47 females, aged (2.25 months- 16 years). Sera of these patients were investigated for hepatitis
markers including HBsAg and A

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Publication Date
Sat Jun 15 2024
Journal Name
Obstetrics & Gynaecology Forum
THE ROLE OF FUNGAL INFECTIONS IN THE PATHOGENESIS OF DIALYSIS-DEPENDENT AND NON-DIALYSIS-DEPENDENT PATIENTS WITH KIDNEY DISEASE
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Abstract The results of isolation, morphological and microscopic diagnosis, Chromic Agar, Vitik technology and Bact Alert showed that the diagnosis of fungi isolated from blood samples of end-stage renal patients who did not undergo dialysis and those who underwent dialysis was 60 samples for each type. The total number of fungal isolates isolated from people who did not undergo dialysis was 26 pathogenic fungal isolates, with a percentage frequency of 43.33%. In this study, 4 genera of pathogenic fungi were identified: Candida spp, Rhodotorula spp, Cryptococcus spp. and Aspergillus spp. The number of Candida isolates reached 13 isolates, with a frequency of 50%. The results also showed that the diagnosed species from the genus Rhodotorula

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Publication Date
Sat Jun 19 2021
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
The Role of Ginkgo biloba Extract as Monotherapy in Improving the Outcomes of Patients with Metabolic Syndrome: A Pilot Comparative Study with Metformin
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The present study evaluates the effects of Ginkgo biloba extract as monotherapy on the glycemic status, insulin resistance (IR), body mass index (BMI), and visceral adiposity index (VAI), in addition to the inflammatory markers, oxidative status and leptin level in patients with metabolic syndrome in comparison with metformin.

The study is a randomized, double-blind pilot study conducted during the period May to September, 2020. Fifty patients were recruited in the study and they were allocated into two groups (25 per each group): Ginkgo biloba and Metformin groups, they received (120 mg Ginkgo biloba extract/ capsule) and (500 mg Metformin/ capsule) respectively; orally as a single dose for 90 days. Blood samples were taken at z

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Publication Date
Wed Aug 30 2023
Journal Name
Baghdad Science Journal
Biochemical Action of Vaccines in Iraqi Patients with COVID-19 Infection
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      The aim of the present study is to compare the biochemical action of the three vaccines taken in Iraq: Pfizer Biontech, AstraZeneca Oxford and Sinopharm based on biochemical parameters. Seventy COVID-19 Iraqi patients ( males and females ) were participated in the present study and classified into 7 groups : Gc :  COVID-19 patients ( without vaccine ) , Gp1: COVID-19 patients took one dose of Pfizer Biontech, Gp2 : COVID-19 patients took two doses of Pfizer Biontech, Ga1 : patients took one dose of AstraZeneca Oxford vaccine , Ga2: patients took two doses of AstraZeneca Oxford vaccine , Gs1 : patients took one dose of Sinopharm vaccine and Gs2:

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Publication Date
Sun Jul 03 2016
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Indications and complications of peritoneal dialysis in children with acute renal failure, a single center experience
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Background: Peritoneal dialysis (PD) is the preferred and convenient treatment modality for acute renal failure (ARF) in children and hemodynamically unstable patients, because of its inherent advantages: technique can be initiated simply and quickly, no highly trained personnel nor expensive and complex apparatus are required and systemic anticoagulation is not needed.
Objectives: is to highlight the role of peritoneal dialysis in management of children with acute renal failure and to determined its complications.
Patients and methods: A retrospective study was carried out from 20th April 2012 till1st May 2014 ,on children with acute renal failure admitted to nephrology unit in Child Welfare Teaching Hospi

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Publication Date
Fri Jan 01 2021
Journal Name
Materials Today: Proceedings
Impact of phosphate ester addition on the cytotoxicity of heat cured denture base material
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This study aims to evaluate and compare the cytotoxicity and biocompatibility of a modified heat-cured acrylic denture base material containing 15% phosphoric acid 2-hydroxyethyl methacrylate ester (PA2HEME) with those of nonmodified PMMA. Discs with a diameter of 12 mm and a thickness of 2 mm were prepared using a heat-cured PMMA denture base material and divided into control and experimental groups. The experimental group was modified with 15% phosphoric acid 2-hydroxyethyl methacrylate ester (PA2HEME). The modified and nonmodified materials were tested via FTIR, and the effect of modification on surface roughness was evaluated with AFM. An in vitro test was conducted to examine the cytotoxicity and biocompatibility of heat-cured acry

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Publication Date
Sat Dec 21 2024
Journal Name
Journal Of Physical Education
The Effect Of Absolute Strength Training On Knee Injuries Rehabilitation And Special Strength In Muay Thai Fighters
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Publication Date
Wed Oct 10 2018
Journal Name
Al-kindy College Medical Journal
Microfracture Arthroscopy Efficacy In Treatment Of Articular Cartilage Insult Of Knee
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Background: The treatment of articular cartilage defects is one of the most clinical challeng for orthopedic surgeons. Articular cartilage is a highly organized tissue with complex biomechanical properties and substantial durability. However, it has a poor ability for healing, and damage from trauma or degeneration can result in morbidity and functional impairment. debilitating joint pain, dysfunction, and degenerative arthritis                                                                           Objectives: The purpose of study is to show effectiveness of micro fracture arthroscopy as a method of treatment for such problem . Type of the study: Cros

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Publication Date
Sat Oct 01 2022
Journal Name
Baghdad Science Journal
The Role of Serum Chitinase-3-Like 1 Protein (YKL-40) Level and its Correlation with Proinflammatory Cytokine in Patients with Rheumatoid Arthritis
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Chitinase-3-like 1 protein (YKL-40) is a glycoprotein primarily produced in the arthritic joint and plays a crucial role in inflammatory processes. The aim of the study is to establish the role of YKL-40 as a biomarker for rheumatoid arthritis (RA) compared to proinflammatory biomarkers and disease activity. The study included 58 patients and 18 control. Diseases activity score (DAS-28) and clinical disease activity index (CDAI) were measured. Serum level of YKL-40, tumor necrosis factor-α (TNF-α), interleukin-1B (IL-1β), erythrocyte sedimentation (ESR), rheumatoid factor (RF), C-reactive protein (CRP), and anti-citrullinated protein antibody (ACPA) were assessed. The results showed that the median serum YKL-40 level which was 5.42 

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Publication Date
Sat Jan 01 2011
Journal Name
Journal Of Environmental Engineering
Influence of Clay Lens on Migration of Light Nonaqueous Phase Liquid in Unsaturated Zone
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