Back ground: Although adult stem cells possess plasticity that permit differentiation along new lineages, production of exocrine and endocrine pancreatic cells and insulin-secreting beta-cells from adult non pancreatic stem cells has been considered controversial. We present that highly purified adult rat hepatic oval stem cells, which are capable of differentiation to hepatocytes and bile ducts epithelium, can also trans-differentiate into pancreatic exocrine-endocrine tissue, when homogenized hepatic tissue is implanted into subcutaneous tissue .
Methods and Materials: A total of 60 adult Swiss albino rats were divided into two groups . Group I , control group (30 animals) was injected with normal saline into the subcutaneous and pancreatic tissue, group II (30 animals) has been exposed to 90% subtotal pancreatectomy with implantation of hepatic tissue homogenate into marked areas of subcutaneous tissue .
Results: During the first three weeks the animals of group II showed both high blood glucose and serum AFP levels, then gradually started to decline and became normal around the period of six weeks and continued being normal till the end of experiment. The histological study showed regeneration and proliferation of small hepatic oval stem cells in the subcutaneous tissue around the second week and trans-differentiation of these cells into islet like cells and acinar like cells around the sixth week.
Conclusions: Hepatic oval stem cell has multipotent character and can differentiate into new-lineages and formation of different clonal cells, such as islet-like cells and acinar cells of the pancreas.
Bitter substances are identified by protein receptors located on surface of taste cell membranes. Mutational polymorphism of the bitter taste receptor (TAS2R38) is a significant determinant in phenylthiocarbamide (PTC) threshold perception. This research's objectives were to find TAS2R38 polymorphisms in Iraqi people and investigate any correlations between genotype and the PTC taste sensitivity. Bitterness sensitivity was determined by assessing the capacity to differentiate and the responsiveness to a representative strip of PTC. Cheek cells samples were collected for DNA extraction, PCR amplification and genotyping. PCR was performed to amplify the short region of the TAS2R38 gene containing the initial polymorphisms of inter
... Show MoreAnd the necessity for the progress of modern societies Because the scientific and objective characteristics that characterize modern societies and distinguish them from traditional societies, Is represented by the extent of its innovative achievements in the theoretical, applied and material scientific and spiritual fields. It should be noted that quality and innovation in modern societies is based on two main pillars, Standard measures for measuring and evaluating innovations to achieve their high quality, And the dissemination of the culture of innovation to spread awareness of the importance and conditions of success, and this is done by the advanced industrial countries, However, despite the great disparity between developed industri
... Show MoreBackground: the integrity of cardiovascular reflexes & autonomic activities can be assessed by different tests and different techniques. However most of these studies carried out on male subject & usually on young group only .very little researches available concerning the differences in cardiovascular reflexes between male & female in different age group.
Aim of study: is to investigate the differences in cardiovascular reflexes in young , old male & female in response to go head up tilting using totally non- invasive system .
Sub. & Methods: this study was carried out in AL-Najaf teaching hospital on 85 normal sub. , 41 males c6 44 females they were divided into two age groups (20-40 years) & (41-60 years)
Objective(s): The aim of the study was to identify the prevalence of overweight and obesity in adolescence and
to estimate the effect of socio- demographic and health behaviors that predicting obesity in adolescents.
Methodology: A cross-sectional descriptive study was being carried out at three public Arabic secondary
schools in Erbil city from October 1
st 2010 to January 30th 2011. A systematic randomly sample size of 461 students
was selected.
Results: In this study, the age of (46.2%, 122) of males students were ranged between (17- 18.9) years old compared
to females students (74.1%, 146) their age ranged between (15 -16.9) years old. About (3.4%, 9) of males
adolescents having overweight while all female ado
Federal oversight is successful in collecting taxes when it saves time and money, and the majority of federal systems tend to adopt direct administration in the application of federal tax laws to finance public expenditure. Central control will prevent tax competition between regions, and administrative corruption.
In Iraq, regional governments are responsible for collecting federal taxes and under the supervision of the Financial Control Bureau, and the reform of supervision requires the rehabilitation of the administration, the adoption of information systems, and the reduction of bureaucracy, and the transparency and federal coordination.
God, may He be glorified and exalted be He, has given every human being the right to life and a dignified life, and has warned against transgression against any of its sanctities without a legitimate right. No one, regardless of his status or authority, can deprive a person of his rights that the Sharia came to preserve, and whoever does that has declared all people to war, as all humanity is in solidarity. In raising the hand that is simplified to harm a person and oppress him unjustly and exalted in the land.
If this is the case, the Sharia came to establish the right of people, groups and individuals, to defend their sanctities, preserve their security, recover their usurped rights, repel the aggression of the aggressors, and oppre
Copper is a cheaper alternative to various noble metals with a range of potential applications in the field of nanoscience and nanotechnology. However, copper nanoparticles have major limitations, which include rapid oxidation on exposure to air. Therefore, alternative pathways have been developed to synthesize metal nanoparticles in the presence of polymers and surfactants as stabilizers, and to form coatings on the surface of nanoparticles. These surfactants and polymeric ligands are made from petrochemicals which are non- renewable. As fossil resources are limited, finding renewable and biodegradable alternative is promising.The study aimed at preparing, characterizing and evaluating the antibacterial properties of copper nanoparticle
... Show MoreThe impact of undergraduate research experiences on students' academic development and retention in STEM fields is significant. Students' success in STEM fields is based on developing strong research and critical thinking skills that make it essential for students to engage in research activities throughout their academic programs. This work evaluates the effectiveness of undergraduate research experiences with respect to its influence on student retention and academic development. The cases presented are based on years of experience implementing undergraduate research programs in various STEM fields at Colorado State University Pueblo (CSU Pueblo) funded by HSI STEM Grants. The study seeks to establish a correlation between students' reten
... Show More