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The Diagnostic Yield of Open Lung Biopsy in relation to clinical and radiological features in Patients with Suspected Interstitial Lung Disease
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Background: The diagnosis of interstitial lung disease (ILD) is frequently delayed, because clinical clues are neglected and respiratory symptoms are ascribed to more common pulmonary diagnosis such as asthma and chronic obstructive pulmonary disease in the primary care setting.
Objective: To evaluate the diagnostic yield of open lung biopsy in patients with suspected ILD in relation to clinical and radiological features.
Patients and methods: Thirty-five patients were admitted with suspected interstitial lung disease (ILD), and scheduled for open lung biopsy (OLB) in Ghazi AL-Hariri hospital for surgical specialty, were included in this study. Data collected from the patient's files (who were subjected to open lung biopsies which had been histopathologically studied in the period from 1st of January 2013 to 31st of May 2015) and were studied retrospectively.
Results: There were 11 (31.4%) males and 24( 68.6%) females, the mean age was 46±14 years , dyspnea was the common presenting symptoms in patients 24(68.6%) , dry cough was the presenting symptoms in10 (28.6%)patients , bilateral diffuse crepitations were heard in 20 (57.2%) patients, bilateral fine basal crepitation were heard in 11 (31.4%) , clubbing with bilateral fine basal crepitations heard in 4 (11.4%) ,chest-x- rays findings were: lower zone infiltration in 11 (31.4%), reticulonodular infiltration in 10 (28.6), nodular infiltration in8 (22.9%) and opacities in6 (17.1%). CT findings were: basal infiltration in11 (31.4%), reticulonodular infiltration in 10 (28.6%), nodular infiltration in 8 (22.9%) and ground glass appearance s in 6 (17.1%). Histopathological examination (obtained from Open lung biopsy) results were: had usual interstitial pneumonia (idiopathic pulmonary fibrosis) 21(60%), 7 (20%) metastasis, 5 (14.3%) pulmonary TB and 2(5.7%) broncho-alveolar cell carcinoma.
Conclusion: Open lung biopsy can give a high diagnostic yield and confirm or alters the diagnosis in a significant number of patients with suspected interstitial lung diseases. The usual interstitial pneumonia pattern is the commonest histopathologic pattern seen in ILD patients.

 الخلفية: تشخيص أمراض الرئة الخلالي كثيرا ما يتأخر، لأنه يتم إهمال االاعراض السريرية والأعراض التنفسية, تعزى إلى تشخيص امراض  الرئة الأكثر شيوعاً مثل الربو ومرض انسداد الشعب الهوائية المزمن في إطار الرعاية الصحية الأولية.

الهدف: تقييم العائد التشخيصي لخزعة الرئة المفتوحة في المرضى الذين يعانون من اشتباه في امراض الرئة الخلالي  بالسمات السريرية والإشعاعية.

المواضيع والأساليب:  شملت الدراسة خمسة وثلاثون مريضا ممن لديهم  أمراض الرئة الخلالي المشتبه فيه، والمقررلهم خزعة الرئة المفتوحة (OLB) في مستشفى غازي الحريري للتخصصات الجراحية.تم جمع البيانات من ملفات المريض (الذي تعرض لفتح خزعات الرئة والتي درست الفحص النسيجي له للفترة من الأول كانون الثاني/يناير 2013 إلى 31 مايو عام 2015)، وقد تم  دراستهم  باثر رجعي .

النتائج: اظهرت النتائج الذكور 11 (31.4%) والإناث 24(68.6%) ، كان متوسط العمرلهم 46±14 سنة، ضيق التنفس كان اكثر الأعراض الشائعة في 24 مريض  (68.6%) ، والسعال الجاف عند 10مرضى (28.6%) ، سماع قرقعة منتشرة  في كلا الرئتين  في20 مريض  (57.2%) ، سماع قرقعة  القاعدية في  كلا الرئتين في 11  مريض(31.4%)، تضخم اظافر اليد مع قرقعة قاعدية سمعت في 4 مرضى (11.4%)   ، وكانت نتائج أشعة الصدر ترشح في الجزء الاسفل للرئة عند  11مريض (31.4%)، ترشح شبكي- عقدي في  مرضى10 (28.6)، ترشح عقدي في 8 مرضى (22.9%) ونسبة تظليل في 6 مرضى (17.1%).  وكانت نتائج الأشعة المقطعية: ترشح القاعدية في11 مريض (31.4%)، ترشح شبكي عقدي في 10مرضى (28.6%)، ترشح عقدي في 8 مرضى (22.9%) ومظهر  زجاج الأرض s في 6مرضى (17.1%). وكانت نتائج الدراسة النسيجية التي تم الحصول عليها من خزعة الرئة المفتوحة: كان 21 (60%) الالتهاب الرئوي الخلالي المعتادة (تليف رئوي مجهول السبب)، 7مرضى ورم خبيث ثانوي (20%)، السل الرئوي5 (14.3%)وورم  الخلية السنخية القصيبية 2(5.7%).

الاستنتاج: خزعة الرئة المفتوحة يمكن أن تعطي نتيجة تشخيصيةعالية ,حيث تؤكد أو تغير التشخيص في عدد كبير من المرضى الذين يعانون من أمراض الرئة الخلالي المشتبه فيهم. النمط المعتاد من الالتهاب الرئوي الخلالي هو نمط الأنسجة الأكثر شيوعاً ينظر في مرضى أمراض الرئة الخلالي.

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Publication Date
Sat Jul 08 2017
Journal Name
Research Journal Of Pharmaceutical , Biological And Chemical Sciences
Assessment activity and Partial purification of Alkaline phosphatase (AIP) from sera of patients with celiac disease
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Publication Date
Sat Jan 11 2025
Journal Name
Journal Of Baghdad College Of Dentistry
ABO Blood Type in Relation in Relation to Caries Experience and Salivary Physicochemical Characteristic among College Students at Al-Diwania Governorate in Iraq
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Background: (ABO) Blood type have an effect on general health including oral health as salivary physicochemical characteristics differ among different type of blood and as consequence these affect the severity of dental caries. The aim of the present study is an assessment of the prevalence of caries experience among different blood type in relation to salivary physicochemical characteristic. Materials and Methods: Two hundred and fifty females' college students in Al-Qadisyia University aged 18 years old were selected on random basis; they were divided to four groups according to their blood type, Dental experience was diagnosed and recorded according to DMFs (Mülemman, 1976) Index, this allows recording decayed lesion by severity. A su

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Publication Date
Wed Dec 14 2016
Journal Name
Journal Of Baghdad College Of Dentistry
Personality Types in Relation to the Periodontal Health Status and Salivary Dehydroepiandrosterone among Teachers in Baghdad City
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Background: The individual differences in emotional and behavioral style can be examined through personality instruments. These differences may explain the health status of the individuals. The purpose of the present study was to assess the influence of Personality Types on gingival and periodontal health status among teachers in Baghdad city in relation to selected salivary hormone (Dehydroepiandrosterone). Materials and methods: Females teachers 534 of randomly selected schools were subjected to personality questionnaire using The Riso-Hudson Enneagram Type Indicator. Teachers were examined to estimate the periodontal status according to the Community Periodontal Index (CPI). A group of teachers were selected for salivary analysis of Dehy

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Publication Date
Sun Feb 25 2024
Journal Name
Baghdad Science Journal
Early Diagnose Alzheimer's Disease by Convolution Neural Network-based Histogram Features Extracting and Canny Edge
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Alzheimer's disease (AD) increasingly affects the elderly and is a major killer of those 65 and over. Different deep-learning methods are used for automatic diagnosis, yet they have some limitations. Deep Learning is one of the modern methods that were used to detect and classify a medical image because of the ability of deep Learning to extract the features of images automatically. However, there are still limitations to using deep learning to accurately classify medical images because extracting the fine edges of medical images is sometimes considered difficult, and some distortion in the images. Therefore, this research aims to develop A Computer-Aided Brain Diagnosis (CABD) system that can tell if a brain scan exhibits indications of

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Publication Date
Fri Dec 07 2018
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Effects of Aldosterone, Osteoprotegerin and Fibroblast Growth Factor-23 and Some Biochemical Markers in Chronic Kidney Disease Patients (Stage II-IV) among Patients with or without Cardiovascular Events
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Chronic Kidney Disease (CKD) is a public health problem and many studies support the link between kidney dysfunction and cardiovascular events.  Aldosterone has been shown for decades that a plasma aldosterone concentration is elevated in CKD. Whilst, Osteoprotegerin (OPG), after its capacity to protect bone, also osteoprotegerin is elevated in patients with chronic kidney disease (CKD), where it could predict the deterioration of kidney function, cardiovascular, vascular events and all-cause mortality. On the other hand, fibroblast growth factors (FGFs), in patients with CKD, its levels seem to increase progressively as kidney function worsens. The aim of the present study is to assess the correlations between serum osteoprotegerin

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Publication Date
Thu Jun 01 2017
Journal Name
Journal Of Economics And Administrative Sciences
Customers emotional blackmail and reduce it the new product- study of the opinions of a sample of customers who deal with peak economy for household items in najaf al Ashraf
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The challenges facing today's multi-customer and this is due to the multiplicity of products and speed in launching new products so search came to reveal the  reveal the of the new product classification standards through a relationship (good products, low interest products, useful products and products desired) and the customer emotionally blackmail through deportation (fear, obligation and guilt). dentified the problem of the research in several questions focused on the nature of the relationship between the variables of research, and for that outline supposedly to search it expresses the head of one hypothesis and branched out of which four hypotheses subset, but in order to ensure the validity of the ass

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Publication Date
Fri Jun 16 2023
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Clinical significance of Osteoprotegerin, Vitamin D, Obestatin and some biochemical variables in Kidney failure Patients
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Chronic kidney disease (CKD) is described as an abnormalities of renal function, existing for a long period of time. By reason of the early grades of Chronic kidney disease can be experiences no symptoms, its premature identification is strenuous. initial stage CRD can cause various complications, such as anemia, matabolyic disorders of bone mineral. The study was done to assess the effect the chronic renal disease stage on the Osteoprotegerin, 1,25 dihydroxyvitamin D, Obestatin levels and some biochemical parameters in patients not undertaken dialysis therapy. In this case-control study fifty-five patients with Kidney failure and fourty healthy people were examined. Circulating concentrations of Osteoprotegerin, 1,25 dihydroxyvitamin D

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Publication Date
Thu Jan 30 2020
Journal Name
Al-kindy College Medical Journal
Conversion Rate from Laparoscopic to open Cholecystectomy in AL-kindy Teaching Hospital, Baghdad
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Background: laparoscopic cholecystectomy (LC) is getting popularity for the treating of symptomatic gall bladder disease; conversion from laparoscopic to open cholecystectomy (OC) is also common.

Objective : To find out the prevalence of causes, risk factors of conversion from LC to OC among  patient suffering from gall bladder disease, and  to explore the most common causes of conversion from laparoscopic to open cholecystectomy.

Methods: This prospective study was conducted in the department of general surgery at Alkindy teaching hospital from first of January 2016 to the end of December 2017 .Nine hundred twenty patient were included. Patient age, gender, his

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Publication Date
Sun Apr 01 2012
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Treatment Of Subclinical Epileptic Discharges Affects Cognitive Functions In Epileptic Patients.
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Background: EEG recording showed a definite relationship between epileptiform EEG discharges and cognitive impairments (transient cognitive impairment “TCI”), since interictal spikes, which correspond to a large intracellular depolarization with evoked action potentials, in many ways mimic a “miniseizure.” Interictal spikes can result in transitory cognitive impairment with the type of deficit dependent on where in the cortex the spike arises. The interictal spikes, particularly if frequent and widespread, can impair cognitive abilities, through interference with waking learning and memory, and memory consolidation during sleep.
Objectives: the aim of this study is to evaluate the effect of subcli

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Publication Date
Tue Nov 30 2021
Journal Name
Research Journal Of Pharmacy And Technology
Diagnostic approach to Perimenopausal bleeding by Pipelle or Dilatation and Curettage
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Perimenopausal bleeding, is a very common problem, which is an alarming symptom for both; women and their doctors because of the rising fears of cellular changes or tumor of endometrium. In our study we tried to prove that collecting endometrial samples using the outpatient method of Pipelle is as effective as collecting the endometrial samples in the traditional method of Dilation and Curettage (DandC) in operation theatre which necessitates general anesthesia. Ninety four patients more than 40 years old were included in the study, all of them were complaining of abnormal uterine bleeding (pregnant ladies and ladies using hormonal contraception were excluded from the study) and endometrial samples were collected first in outpatient

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