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The Diagnostic Yield of Open Lung Biopsy in relation to clinical and radiological features in Patients with Suspected Interstitial Lung Disease
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Background: The diagnosis of interstitial lung disease (ILD) is frequently delayed, because clinical clues are neglected and respiratory symptoms are ascribed to more common pulmonary diagnosis such as asthma and chronic obstructive pulmonary disease in the primary care setting.
Objective: To evaluate the diagnostic yield of open lung biopsy in patients with suspected ILD in relation to clinical and radiological features.
Patients and methods: Thirty-five patients were admitted with suspected interstitial lung disease (ILD), and scheduled for open lung biopsy (OLB) in Ghazi AL-Hariri hospital for surgical specialty, were included in this study. Data collected from the patient's files (who were subjected to open lung biopsies which had been histopathologically studied in the period from 1st of January 2013 to 31st of May 2015) and were studied retrospectively.
Results: There were 11 (31.4%) males and 24( 68.6%) females, the mean age was 46±14 years , dyspnea was the common presenting symptoms in patients 24(68.6%) , dry cough was the presenting symptoms in10 (28.6%)patients , bilateral diffuse crepitations were heard in 20 (57.2%) patients, bilateral fine basal crepitation were heard in 11 (31.4%) , clubbing with bilateral fine basal crepitations heard in 4 (11.4%) ,chest-x- rays findings were: lower zone infiltration in 11 (31.4%), reticulonodular infiltration in 10 (28.6), nodular infiltration in8 (22.9%) and opacities in6 (17.1%). CT findings were: basal infiltration in11 (31.4%), reticulonodular infiltration in 10 (28.6%), nodular infiltration in 8 (22.9%) and ground glass appearance s in 6 (17.1%). Histopathological examination (obtained from Open lung biopsy) results were: had usual interstitial pneumonia (idiopathic pulmonary fibrosis) 21(60%), 7 (20%) metastasis, 5 (14.3%) pulmonary TB and 2(5.7%) broncho-alveolar cell carcinoma.
Conclusion: Open lung biopsy can give a high diagnostic yield and confirm or alters the diagnosis in a significant number of patients with suspected interstitial lung diseases. The usual interstitial pneumonia pattern is the commonest histopathologic pattern seen in ILD patients.

 الخلفية: تشخيص أمراض الرئة الخلالي كثيرا ما يتأخر، لأنه يتم إهمال االاعراض السريرية والأعراض التنفسية, تعزى إلى تشخيص امراض  الرئة الأكثر شيوعاً مثل الربو ومرض انسداد الشعب الهوائية المزمن في إطار الرعاية الصحية الأولية.

الهدف: تقييم العائد التشخيصي لخزعة الرئة المفتوحة في المرضى الذين يعانون من اشتباه في امراض الرئة الخلالي  بالسمات السريرية والإشعاعية.

المواضيع والأساليب:  شملت الدراسة خمسة وثلاثون مريضا ممن لديهم  أمراض الرئة الخلالي المشتبه فيه، والمقررلهم خزعة الرئة المفتوحة (OLB) في مستشفى غازي الحريري للتخصصات الجراحية.تم جمع البيانات من ملفات المريض (الذي تعرض لفتح خزعات الرئة والتي درست الفحص النسيجي له للفترة من الأول كانون الثاني/يناير 2013 إلى 31 مايو عام 2015)، وقد تم  دراستهم  باثر رجعي .

النتائج: اظهرت النتائج الذكور 11 (31.4%) والإناث 24(68.6%) ، كان متوسط العمرلهم 46±14 سنة، ضيق التنفس كان اكثر الأعراض الشائعة في 24 مريض  (68.6%) ، والسعال الجاف عند 10مرضى (28.6%) ، سماع قرقعة منتشرة  في كلا الرئتين  في20 مريض  (57.2%) ، سماع قرقعة  القاعدية في  كلا الرئتين في 11  مريض(31.4%)، تضخم اظافر اليد مع قرقعة قاعدية سمعت في 4 مرضى (11.4%)   ، وكانت نتائج أشعة الصدر ترشح في الجزء الاسفل للرئة عند  11مريض (31.4%)، ترشح شبكي- عقدي في  مرضى10 (28.6)، ترشح عقدي في 8 مرضى (22.9%) ونسبة تظليل في 6 مرضى (17.1%).  وكانت نتائج الأشعة المقطعية: ترشح القاعدية في11 مريض (31.4%)، ترشح شبكي عقدي في 10مرضى (28.6%)، ترشح عقدي في 8 مرضى (22.9%) ومظهر  زجاج الأرض s في 6مرضى (17.1%). وكانت نتائج الدراسة النسيجية التي تم الحصول عليها من خزعة الرئة المفتوحة: كان 21 (60%) الالتهاب الرئوي الخلالي المعتادة (تليف رئوي مجهول السبب)، 7مرضى ورم خبيث ثانوي (20%)، السل الرئوي5 (14.3%)وورم  الخلية السنخية القصيبية 2(5.7%).

الاستنتاج: خزعة الرئة المفتوحة يمكن أن تعطي نتيجة تشخيصيةعالية ,حيث تؤكد أو تغير التشخيص في عدد كبير من المرضى الذين يعانون من أمراض الرئة الخلالي المشتبه فيهم. النمط المعتاد من الالتهاب الرئوي الخلالي هو نمط الأنسجة الأكثر شيوعاً ينظر في مرضى أمراض الرئة الخلالي.

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Publication Date
Wed Oct 01 2008
Journal Name
Journal Of The Faculty Of Medicine Baghdad
INCIDENCE OF POST-OPERATIVE DEEP VEIN THROMBOSIS IN PATIENTS WITH LOWER LIMB OPEN FRACTURE
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Background: Venous thromboembolic (VTE) disease with i t ' s h i g h morbidity and mo r t a l i t y is currently one of the most serious postoperative complication, (DVT) can lead to
fatal pulmonary embolism (PE). or the development of post thrombotic syndrome.
Patients and methods: This is a prospective study which was carried on 85 patients had s i n g l e lower l i m b open fracture with no other major i n j u r i e s in other sites of body
(with the exception of superficial wounds or b r u i s e s ) .They were d i v i d e d i n t o groups according to age, gender, weight, type of fracture, methods of immobilization, duration of
h o s p i t a l i z a t i o n , duration of operation. All the patients includin

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Publication Date
Sun May 10 2020
Journal Name
Baghdad Science Journal
Prevalence of Quinolones Resistance Proteins Encoding Genes (qnr genes) and Co-Resistance with β-lactams among Klebsiella pneumoniae Isolates from Iraqi Patients
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This study investigated the prevalence of quinolones resistance proteins encoding genes (qnr genes) and co-resistance for fluoroquinolones and β-lactams among clinical isolates of Klebsiella pneumoniae.  Out of 150 clinical samples, 50 isolates of K. pneumoniae were identified according to morphological and biochemical properties. These isolates were collected from different clinical samples, including 15 (30%) urine, 12 (24%) blood, 9 (18%) sputum, 9 (18%) wound, and 5 (10%) burn. The minimum inhibitory concentrations (MICs) assay revealed that 15 (30%) of isolates were resistant to ciprofloxacin (≥4µg/ml), 11 (22%) of isolates were resistant to levofloxacin (≥8 µg/ml), 21 (42%) of isolates were re

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Publication Date
Sun Oct 07 2012
Journal Name
Journal Of Educational And Psychological Researches
The effect of music therapy in lowering high blood pressure in patients with diseases of sugar
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      Faces of the individual in his life many stressful events, which includes expertise undesirable, and events may involve a lot of sources of tension and the risk factors and threats in all areas of life, and this would make the stressful events play a role in the genesis of many diseases physical.            

The high blood pressure is one of the most Actual manifestations of mental stress in the present scale physical disorders which may frequently in men relative to women, which may be caused by spasms in the blood vessels.      

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Publication Date
Sun Dec 02 2018
Journal Name
Journal Of The College Of Education For Women
Political Thought in Russia During the 21st Century, Targets and Features
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The features of strategic thought transformation in Russia based on attempt confirm the Russian influenced on Region of Eastern Europe through series of common defense treaties and mutual security between USSR and another states this treaties emphasis size on direct Russian supervision on these states in addition, Russia in trusted to formation communism regimes in its vital space, Russia inherited the status of former USSR in political and economic levels.

           Shortly we can see that Russia witnessed large Transformation in political strategic thought as a result of change in internal strategic environment and change of nature understanding which influenced on Russia. This

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Publication Date
Sat Jan 04 2025
Journal Name
Journal Of Baghdad College Of Dentistry
Establishment of the possible association between the presence of Helicobacter pylori in the saliva and gastric biopsy by using polymerase chain reaction technique in association with oral manifestation of peptic ulcer disease
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Background: Helicobacter pylori are important gastrointestinal pathogen associated with gastritis, peptic ulcers, and an increased risk of gastric carcinoma. There are several popular methods for detection of H. pylori (invasive and non-invasive methods) each having its own advantages, disadvantages, and limitations, and by using PCR technique the ability to detect H. pylori in saliva samples offers a potential for an alternative test for detection of this microorganism. Materials and methods: The study sample consists of fifty participants of both genders, who undergo Oesophageo-gastrodudenoscopy at the Gastroenterology Department of Al-Kindy Teaching Hospital Baghdad/ Iraq, during five months period from January 2014 to May 2014. They we

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Publication Date
Sun Apr 02 2017
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Surgical management of staple line leak after laparoscopic sleeve gastrectomy
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Background: Laparoscopic sleeve gastrectomy (LSG)is derived from the biliopancreatic diversion with duodenal switch operation(BPD-DS). Specific and potentially severe complications of LSG are bleeding from the staple line and staple line leakage (SLL). A staple line leak may result in severe morbidity with potential sepsis and multi- organ failure.
Objectives: To review our experience with the definitive surgical management of staple line leak Post sleeve gastrectomy and its outcomes.
Patients and methods: retrospective review of patients who underwent definitive surgical treatment of staple line leak post sleeve gastrectomy from May 2014 till June 2016 at Saint Raphael center of morbid obesity, Primary surgery was laparoscopic sle

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Publication Date
Fri Jun 17 2022
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Development of 5-FU Loaded poly lactic-co-glycolic acid Nanoparticles for Treatment of Lung Cancer
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Non-Small Cell Lung Cancer (NSCLC) accounts for about 84% of all lung cancer types diagnosed so far. Every year, regardless of gender, the NSCLC targets many communities worldwide. 5-Fluorouracil (5-FU) is a uracil-analog anticancer compound. This drug tends to annihilate multiple tumour cells. But 5-FU's most significant obstacle is that it gets very easily metabolized in the blood, which eventually leads to lower anticancer activity. Therfore a perfect drug delivery system is needed to overcome all the associated challenges.

In this experiment, an attempt was made to prepare 5-FU loaded poly lactic-co-glycolic acid  nanoparticles using solvent evaporation method and subsequently observed the effect of molecular weight of poly l

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Publication Date
Thu Jun 25 2020
Journal Name
International Journal Of Drug Delivery Technology
The Effects of Salvia officinalis Gel as an Adjunct to Scaling and Root Planning in Patients with Periodontitis (Clinical and Immunological Study)
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Background: Phytotherapy is the usage of herbal species with medicinal properties for the management of various diseases. Gingivitis and periodontitis are diseases that involve the role of both the bacteria and the host immune response. Over the years, various researches have shown the importance of herbal products in the management of periodontal diseases. Aims of the study: To evaluate the efficacy of locally applied Salvia officinalis gel as adjunctive in the treatment of chronic periodontitis. Subjects and methods: Fourteen patients (10 males and 4 females) with chronic periodontitis were enrolled in the present study with total number of twenty-eight periodontal pockets utilizing a split mouth design, the pockets were divided i

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Publication Date
Sat Apr 02 2022
Journal Name
Neuroquantology
The Role of Neudesin as a Novel Biomarker – in Iraqi Patients with Parkinson's Disease and Osteoporosis
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Neuron-derived neurotrophic factor [NENF], a human plasma neurotrophic factor, also increases neurotrophic activity in conjunction with Parkinson's disease-related proteins in Neudesin. Although Neudesin (neuron-derived neurotrophic secreted protein) is a member of the membrane-associated progesterone receptor (MAPR) protein subclass, it is not evolutionary related to the other members of the same family. The expression of Neudesin is found in both brain and spinal cord from embryonic stages to adulthood, as w Neudesin levels in Parkinson's patients with osteoporosis disease and Parkinson's patients without osteoporosis disease, as well as the relationship between Neudesin levels, Anthropometric and Clinical Features (Age, Gender, BMI) and

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Publication Date
Mon Aug 01 2016
Journal Name
Journal Of Economics And Administrative Sciences
Evaluating health services in the private suites for governmental hospitals from the perspective of patients
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ABSTRACT                                                                                            

The study aims to identify the level of health services provided in private suites to government hospitals from the perspective of the recipi

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