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Thyroid Disorders and the Level of Malondialdehyde
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Background: Free radicals have been implicated in many pathological processes, including ischemia, inflammation, and malignancy. The free radicals may affect tissues damage by lipid
peroxidation which generate malondialdehyde (MDA) as a by byproduct of the reaction. The objective of this study is to examine the dynamics of lipid peroxidation in patients with
thyroid disorders using the measurement of malondialdehyde level as a marker for the degree of thyroid disorder.
Methods: Two hundred and forty five subjects were enrolled in this study. Hundred and ninety five were patients with different thyroid disorders (88 yperthyroidism, 63 hypothyroidism and 44 thyroid carcinoma) the remaining 50 subjects were healthy ones without any apparent functional disorders served as a control. Malondialdehyde (MDA) level was estimated in the sera of all subjects.
Results: A significant increase in the level of serum MDA concentration was observed in patients with all types of thyroid disorders as compared with the control groups.
Conclusion: The findings obtained showed a high rate of lipid peroxidation.

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Publication Date
Sun Oct 01 2017
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Pre-operative serum TSH level estimation for predicting malignant nodular thyroid disease
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Publication Date
Mon Oct 17 2022
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Evaluation of the Role of Serum Malondialdehyde in the Pathogenesis of Diabetic Retinopathy
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Background:  The most typical consequence of diabetes mellitus is diabetic retinopathy. An important part of the etiology of diabetes and diabetic retinopathy is played by oxidative stress. Malondialdehyde is a dialdehyde that is moderately toxic and is frequently used as a marker for oxidative stress as well as lipid peroxidation.                    

Objectives: To assess the serum malondialdehyde levels in diabetic patients with and those without retinopathy and to compare these levels to controls .In additions to, investigate the relationship between serum malondialdehyde level and long glycemic control, the glycated hemoglobin (HbA1c).

Pati

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Publication Date
Tue Jan 02 2007
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Adrenal Disorders, Surgical Approaches and Postoperative complications
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Backgraound: Adrenal disorders in surgical practice are presented either as hyperfunctional disorders or non functional disorders (incidentalomas). Functionally, medullary tumors (pheochromocytoma) result in excess secretion of catecholamines(l), on the other hand, functioning adrenocortical tumors could secrete excess of cortisol (Cushing syndrome), aldosterone (Conn's syndrome) or sex hormones (virilizing syndromes). (2
The aim of our study is to identify and to show our experience in the surgical approach and postoperative complications of adrenal disorders.
Patients & methods: This is a prospective study of 20 cases diagnosed as having adrenal disorders, admitted and evaluated in Baghdad T

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Publication Date
Mon May 15 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Studies on the Relationship Between Chromium(III) ion and Thyroid Peroxidase Activity in Sera of Patients with Thyroid Dysfunction
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   The  objective of this study was to determine the concentration of trace element chromium(III) and thyroid peroxidase activity in human serum , and    to find a relationship between the concentration of chromium(III) and thyroid peroxidase activity in serum of patients with hypothyroidism, hyperthyroidism and healthy subjects. Serum thyroid peroxidase was measured by enzyme linked radioimmunoassay(ELISA) method and chromium determination was by atomic absorption spectrophotometer .Comparing the values of chromium concentration and thyroid peroxidase activity in both samples showed that there were significant positive correlations between chromium levels and thyroid peroxidase activity(P<0.01, r=0.11).

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Publication Date
Thu Jun 25 2020
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Effects of Two Different Doses of Zinc Sulfate on Serum Troponin I 3 Enzyme Level and Cardiac Malondialdehyde Contents in Mitoxantrone-Induced Cardiotoxicity in Rats
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Abstract

   Mitoxantrone is an antitumor agent used in the treatment of breast and prostate cancer, acute leukemia, lymphoma, and also in the treatment of multiple sclerosis due to its immunosuppressive properties. The mitoxantrone's cardiotoxicity is irreversible, dose-dependent, and it may occur years after treatment. Zinc is considered as an essential mineral for cell division and the synthesis of DNA and protein; furthermore, such mineral has an important role in states of cardiovascular diseases; and may have protective effects in coronary artery disease and cardiomyopathy.

Objective: The current study is designed to investigate effects of two different doses of zinc sulfat

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Publication Date
Sun Jan 05 2014
Journal Name
Journal Of Educational And Psychological Researches
Attention Deficit Hyperactivity Disorders ADHD
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زاد الاهتمام بالأطفال ذوي اضطراب الانتباه المصحوب بالنشاط الزائد نظراً لانتشاره بين الأطفال في عمر المرحلة الابتدائية حيث تراوحت نسبته ما بين  3% إلى 20%  ومعظمهم من الذكور ، وأن انتشاره يقع في مختلف الطبقات الاجتماعية بالنسبة لعوائل هؤلاء الأطفال كما أن المشكلات المتعلقة به لا تنتهي بانتهاء مرحلة الطفولة ، وغالباً ما تمتد إلى مرحلة المراهقة حيث توصل ويز و هتكمانWeiss&Hechtman,1989  إلى أن هناك علامات م

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Publication Date
Thu Oct 01 2009
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Creatine Kinase Activity and Malondialdehyde in the Seminal Plasma of Normospermic Infertile Males
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Background: Normospermia might be a major problem to the doctor and the infertile couple because the male seminal sample has an accepted seminal parameters during the routine seminal examination and the female partner will be claimed for the infertility and she will suffered from coasty, painful, time consuming, non indicated investigations and treatments. Our purpose was to measure sperm creatine phosphokinase (CK) activity, which reflects cytoplasmic retention in immature spermatozoa and malondialdehyde in the seminal plasma which is a marker of oxidative stress in normospermic infertile males' seminal samples.
Patient and methods: Nine infertile men with aberrantly normal standard seminal analysis&nbsp

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Publication Date
Sun Sep 07 2014
Journal Name
Baghdad Science Journal
Correlation between malondialdehyde and metanephrine in patients with acute lymphoblastic leukemia
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Acute lymphoblastic leukemia (ALL) is one of the most common diseases , so in this study the serum level of malondialdehyde and its relationship with metanephrine was investigated in acute lymphoblastic leukemia patients over one month of treatment. Some biochemical parameters (serum glucose , total serum protein , malondialdehyde ,vitamin C, and metanephrine) changed as well as white blood cell count and blood hemoglobinlevelswere analyzed in sixty patients diagnosed with acute lymphoblastic leukemia over one month of treatment compared to healthy control group.Statistically significant increases (p<0.01) in white blood cell (WBC) count, mean concentrations of malondialdehyde (MDA) (p< 0.05) and metanephrine (p< 0.001) were observed in

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Publication Date
Sat Dec 07 2019
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Incidental Thyroid Carcinoma in Patients Treated Surgically for Thyroid Disease
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Background: The occurrence of incidental thyroid cancer (ITC) has increased by three times during the last decades and this rise could be attributed to many factors. To limit the prevalence of ITC with goiter especially nodular goiter, total thyroidectomy can become a procedure of choice.

Objective: To determine the extent of incidental thyroid carcinoma (ITC) and to plan a proper preoperative diagnostic work up and a convenient operative procedure for patients with different thyroid diseases.


Results:
ITC was found in 77 patients (19.15%). While, 63 patients with non-toxic MNG (15.6%), 12 patients with non-toxic solitary thyroid nodule (3%) and two patients (0.5%) wi

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Publication Date
Wed Feb 02 2022
Journal Name
Iraqi Journal Of Science
The role of Helicobacter pylori infection in skin disorders
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This study was amied to determine the relationship between Helicobacter pylori infection and skin disorders, sixty six patients who suffering from skin diseases (Urticaria and atopic dermatitis) who attended at Dermatological Clinic Al-Numan Teaching Hospital. Aged (6--62) years have been investigated and compared to Twenty two samples of apparently healthy individual's were studied as control group . All the studied groups were subjected to measurement of anti- Helicobacter pylori antibodies IgA by Enzyme linked immunosorbent assay (ELISA). The results of current study revealed that there were a significant elevation (P<0.05) in the concentration of H. pylori IgA antibodies in sera of patients with chronic urticaria and atopic dermat

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