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Magnetic resonance imaging in assessment of liver lesions in patients with extrahepatic primary cancer

Background: Liver imaging is commonly undertaken in patients with cancer history because, after lymph nodes, the liver is the most frequently involved organ by metastases
Objectives: The aim of the study was to evaluate the role of liver MRI (magnetic resonance imaging) in characterization and detection of liver lesion in patients with extrahepatic primary
Methods: this is a cross sectional study of 70 patients with extrahepatic liver primary cancer who had their treatment in oncology teaching hospital underwent routine abdominal ultrasound to detect liver lesion(s) and suspicious cases then referred to MRI which was done in Ghazi Alharri and oncology teaching hospital from the period from 1st of September 2015 to end of November 2016, the patients age range from 31 to 75 years
Results: hemangioma is the most common solitary liver lesion in patients with extrahepatic primary cancer which represent 27% of lesions detected followed by simple cyst which represent 13% of the lesions, in another hand solitary metastasis seen in 7% of solitary lesions while metastasis is the leading cause behind multiple hepatic lesions and represent about 38% of lesions seen ,unlike solitary lesions, hemangioma is a rare cause and seen in 7% of cases
Conclusion: MRI is a required adjuvant tool in evaluation of suspicious liver lesion ,its value was illustrated in characterization and diagnosis of liver lesions depending on their appearance in T1 ,T2 and fat suppression T2 sequences in addition to assess their enhancement pattern after dynamic IV( intravenous) contrast injection.

الخلفية: يتم عمل تصوير الكبد عادة للمرضى الذين يعانون من السرطان، لأنه العضو الأكثر اصبابة بانتشار السرطان بعد العقد الليمفاوية.

المقدمة: الهدف من هذه الدراسة هو تقييم دور تصوير الكبد بالرنين المغناطيسي في كشفو توصيف افات الكبد في المرضى الذين يعانون من سرطان اولي خارج الكبد.

المرضى والطرق: هذة هي دراسة مقطعية ل 70 مريضا يعانون من سرطان اولي خارج الكبد والذين كان علاجهم في مستشفى الأورام التعليمي في مدينة الطب ثم خضعوا لفحص الرنين المغناطيسي في مستشفى الشهيد غازي الحريري  ومستشفى الأورام خلال الفترة من 1 سبتمبر 2015 إلى نهاية نوفمبر 2016 وهم من الفئة العمرية بين  31-75 عاما.

النتائج: يمثل الورم وعائي الدموي الأكثر شيوعا من الاورام الانفرادية في الكبد في المرضى الذين يعانون من سرطان خارج الكبد والتي تمثل 27٪ من الآفات اكتشفت يليه كيس بسيط والذي يمثل 13٪ من الآفات الانفرادية المكتشفة، من جهة أخرى انتشار الورم الاولي الوحيد يمثل 7٪ من الآفات الانفرادية، والعكس تماما حيث يكون السبب الرائد وراء الآفات الكبدية المتعددة ويمثل حوالي 38٪ من آفة الكبدد المتعددة ، في حين اخر ان الأورام الوعائية تمثل 7٪ من الحالات المتعددة.

الاستنتاجات: الرنين المغناطيسي هو أداة مساعدة ومطلوبة في تقييم الآفة الكبد المشبوهة، وتتجلى قيمته في توصيف وتشخيص آفات الكبد اعتمادا على مظهرهم في مقاطعT1 ، T2، ومقاطع T2قمع الدهون بالإضافة إلى تقييم نمط اخذها للصبغة بعد الحقن في الوريد والذي يسمي بالفحص الديناميكي .

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Publication Date
Sat Dec 31 2016
Journal Name
Al-kindy College Medical Journal
A Comparison of Sagittal Sections of Short T1inversion Recovery and T2 Weighted Fast Spin Echo Magnetic Resonance Sequences for Detection of Multiple Sclerosis Spinal Cord Lesions

Background: Multiple sclerosis is a chronic autoimmune inflammatory demyelinating disease of the central nervous system of unknown etiology. Different techniques and magnetic resonance image sequences are widely used and compared to each other to improve the detection of multiple sclerosis lesions in the spinal cord. Objective: To evaluate the ability of MRI short tau inversion recovery sequences in improvementof multiple sclerosis spinal cord lesion detection when compared to T2 weighted image sequences. Type of the study: A retrospective study. Methods: this study conducted from 15thAugust 2013 to 30thJune 2014 at Baghdad teaching hospital. 22 clinically definite MS patients with clinical features suggestive of spinal cord involvement,

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Publication Date
Sun Jan 03 2016
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Role of Ultrasound and computed tomography in assessment of abdominal lymphadenopathy and splenomegally in lymphomas

Background: lymph nodes involvement is the most common presentation of abdominal lymphoma; their diagnosis is based on variety of imaging modalities, histopathology of different areas of involvement and stage of the disease.
Objective: to compare the value of abdominal ultrasound (US) and computed tomography (CT) scan in already diagnosed cases of lymphoma and evaluation of lymph nodes and splenic involvement in patients with proved lymphoma.
Patients and methods: thirty patients with lymphoma were gathered from hematological unit in Baghdad teaching hospital retrospectively depending on their histopathology that revealed either Hodgkin lymphoma (HL) or non-Hodgkin lymphoma (NHL) and they were examined by ultrasound and CT scan of

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Publication Date
Wed Jan 02 2013
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Investigation the effect of the alcoholic extract of Zingiber officinale on liver enzymes and oxidative stress during ischemia reperfusion injury

Background: Hepatic ischemia-reperfusion (I/R) injury may occur in a variety of clinical set­tings and this remains a significant problem. Oxygen free radi­cals, produced on reperfusion have been shown to play a major role in hepatic I/R injury. Various therapeutic effects have been described for Zingiber officinale. Additionally, it has been presented that Zingiber officinale has protective effect against ischemia reperfusion injury to various organs. Therefore, it seems possible that the administration of Zingiber officinale might protect the liver against the ischemia reperfusion  injury.

Objectives : To determine whether Zingiber officinale prevents hepatic ischemia-reperfusion injury to the liver.

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Publication Date
Mon Apr 01 2013
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Oxidative Stress and Some Liver Functions Parameters in Patients with Symptomatic Cholelithiasis

Background : Gallstone disease is one of a common surgical problem and one of the most common gastrointestinal diseases throughout the world but its pathogenesis remains unclear. Many theories have been put forward to explain the mechanism of stone formation. The living organism has enzymatic and non-enzymatic antioxidant systems neutralizing the harmful effects of the endogenous oxygen free radicals products. Under certain conditions, the oxidative or anti-oxidative balance shifts towards the oxidative status as a result of increase in oxygen free radicals and/or impairment in antioxidant mechanism.

Objective :To evaluate the oxidative stress markers (total antioxidants capacity and malondialdeh

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Publication Date
Tue Dec 01 2020
Journal Name
Baghdad Science Journal
Prevalence of Diabetes Mellitus in Hepatitis C Patients in Wazirabad Tehsil of Gujranwala District of Pakistan: hepatitis C in Diabetic patients

Hepatitis, a condition of liver’s inflammation that can be self-limiting or, in certain chances, it may lead to liver cancer, fibrosis or cirrhosis. Hepatitis viruses mainly cause hepatitis in the world. People with hepatitis C have predominant chances to develop diabetes as HCV virus participates in causing type 2 diabetes. HCV virus causes pathogenesis in two ways: it either directly destroys the β cells of pancreas or contributes to the specific autoimmunity of β cells. The present cross sectional study was done in Wazirabad Tahsil of Gujranwala District to analyze the percentage of patients suffering from hepatitis C who had the risk of diabetes mellitus. For this research work, demographic information and data about any other me

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Publication Date
Wed Jan 02 2013
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Species of Malassezia associated with psoriatic patients

Background: Malassezia spp. are lipophilic unipolar yeasts recognized as commensals of skin that may be pathogenic under certain conditions. Yeasts of the genus Malassezia are known to be members of the skin micro flora of human and other warm-blooded vertebrates. Psoriasis is a common cutaneous disease of unknown etiology, may be triggered by infections, including those due to fungi.
Materials and methods:
Twenty three patients with psoriasis were included in this study, who attended Al-Kadhumyia teaching hospital / Dermatology department, from the 30th of October 2010 to the 1st of April 2011. Fifteen (15) were males and eight (8)  were females, with the mean ag

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Publication Date
Sun Apr 03 2011
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Serum lipid profile in patients with primary fibromyalgia

Background: Fibromyalgia syndrome (FMS) is a chronic musculoskeletal disorder characterized by wide spread body pain, chronic fatigue, 

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Publication Date
Thu Sep 12 2019
Journal Name
Al-kindy College Medical Journal
The Role of Metformin in patients with Primary Hypothyroidism

Background: Insulin resistance is present in 50% or more of patients with primary hypothyroidism. Metformin can decrease TSH levels in these patients by a complex matter, this can be of great help in clinical practice.

Objective: This study was designed to evaluate the effect of metformin in reducing TSH levels in patients with primary hypothyroidism.

Methods: Hundred patients with primary hypothyroidism, 82 females, 18 males were included in this study, everyone was followed up for two months after adding metformin 850 mg twice daily in addition to thyroxin.

Results: 36 patients (36%) have a normal baseline TSH and no change after 2 months, 64 pa

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Publication Date
Sun Jul 03 2011
Journal Name
Journal Of The Faculty Of Medicine Baghdad
The Role of Resistin in Patients with Primary Fibromyalgia

Background: Fibromyalgia syndrome (FMS) is a common rheumatologic syndrome with multiple manifestations and associated with many diseases, it characterized by chronic wide
spread muscular pain and tenderness. Resistin is an adipokine discovered in 2001 and considered as a link between obesity and type 2 diabetes by antagonizing and resisting the
action of insulin as it name encompass ;resistin (resist insulin) . It is secreted mainly from adipose tissue in mice and from white blood cells besides the adipose tissue in humans.
Research reviled that resistin has a role in some inflammatory diseases like Rheumatoid Arthritis (RA).
Objective: The objective of this study is to measure Resistin concentration and

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Publication Date
Sat Aug 01 2015
Journal Name
Modern Applied Science
A New Method for Detecting Cerebral Tissues Abnormality in Magnetic Resonance Images

We propose a new method for detecting the abnormality in cerebral tissues present within Magnetic Resonance Images (MRI). Present classifier is comprised of cerebral tissue extraction, image division into angular and distance span vectors, acquirement of four features for each portion and classification to ascertain the abnormality location. The threshold value and region of interest are discerned using operator input and Otsu algorithm. Novel brain slices image division is introduced via angular and distance span vectors of sizes 24˚ with 15 pixels. Rotation invariance of the angular span vector is determined. An automatic image categorization into normal and abnormal brain tissues is performed using Support Vector Machine (SVM). St

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