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iqjmc-1057
Possible Association of HLA-DR and DQ Molecules with Autoimmune Hepatitis in Iraqi Patients
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Background: Human leukocyte antigen (HLA) is the most polymorphic genetic system in man. The genes of this region seem to influence susceptibility to certain diseases.
Patients and methods: Polymerase chain reaction-Sequence Specific Primers PCR-SSP is the method used to asses HLA-typing of 100 blood samples of 60 AIH patients and 40 healthy normal controls.
Results: An increased frequency of HLA-DR3, DR4 and DR7 was observed for patients group versus control group with P-value (0.0001, 0.05, and 0.001) respectively, while DR*0211 (DR2) may be formed the basis for protection against the disease. HLA-DQ on the other hand, yielded on association in Iraqi patients with AIH.
Conclusions: This finding demonstrated that HLA-DR3, DR4 and DR7 might play a role in AIH susceptibility.

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Publication Date
Sun Jul 02 2006
Journal Name
Journal Of The Faculty Of Medicine Baghdad
prevalence of hepatitis Band hepatitis C among blood donors in Al Anbar governorate
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Background:

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Publication Date
Fri Jan 13 2023
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Kidney functions and electrolyte disturbance among Iraqi patients with bladder cancer
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Background: Bladder cancer is among the most prevalent cancers worldwide, with 549,393 new cases reported in 2018. Approximately 3% of all new cancer diagnoses and 2.1% of all cancer deaths are due to urinary bladder cancer.

Objectives: This study aims to explore the efficiency of renal system functions as indicated by renal function tests and electrolyte levels among bladder cancer patients.

Methods: All patients in this case-control study were recruited from Ghazi Al-Hariri Hospital for surgical specialties in Baghdad during the period from December 2021 to June 2022. A total of 100 individuals were enrolled in this study and divided into two groups.

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Publication Date
Sat Sep 03 2022
Journal Name
International Journal Of Health Sciences
Correlation between oxidative stress and clopidogrel drug in Iraqi patients with coronary artery disease
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Background: Coronary Artery Disease (CAD) is one of the largest causes of mortality worldwide. Clopidogrel, antiplatelet drug, has been widely used for management of CAD. The current study aimed to investigate the effect of clopidogrel on the oxidative stress in CAD patients. Methods: One hundred CAD patients, who were followed-up for 5 days after receiving clopidogrel, and 50 healthy volunteers were included in this study. Parameters include catalase (CAT), total antioxidant capacity (TAC), total oxidant capacity (TOC), total protein, albumin, and globulins were determined before and after treatment with clopidogrel. Results: CAT, TAC, and Tp were significantly decreased (P<0.0001) in CAD patients compared to healthy control and

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Publication Date
Sun Oct 02 2011
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Carotid Intima-Media Thickness in 100 Iraqi Patients with Hand Osteoarthritis
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Background: Hand osteoarthritis (HOA) is a common joint disorder leading to considerable pain and with substantial impact on hand function. Carotid intima-media thickness (CIMT) is a measurable index of the presence of atherosclerosis. Increased CIMT is associated with increased cardiovascular mortality and morbidity, so early diagnosis and management may improve quality of life.
Objective: To assess the relationship between carotid intima-media thickness (CIMT) and hand osteoarthritis (HOA), and to evaluate the predictors of this relationship.
Patients and Methods: One hundred Iraqi HOA patients and 100 healthy controls were included in this study. Full history was taken and complete clinical examination was done for all patients

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Publication Date
Sun Oct 02 2011
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Factor V Leiden Mutation in Iraqi Patients with Deep Venous Thrombosis.
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Background: Factor V Leiden is considered the most common inherited risk factor for venous thrombosis in Caucasian populations, including those in the Eastern Mediterranean region. While several studies have addressed Factor V Leiden prevalence in patients with venous thrombosis in the Eastern Mediterranean countries, none have been reported from Iraq.
Objective: To study the prevalence of Factor V Leiden in an unselected group of Iraqi patients with Deep Venous thrombosis.
Materials and Methods: A total of 50 unselected patients with deep venous thrombosis referred to the Medical City Teaching Hospital in Baghdad, Iraq, as well as 40 age and sex matched controls, were enrolled. The evaluation included in addition to detailed histo

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Publication Date
Tue Apr 01 2014
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Fibromyalgia Syndrome among Iraqi Patients with Knee Osteoarthritis.
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Back ground: Fibromyalgia syndrome (FMS) is a common chronic musculo-skeletal disorder resulting in chronic widespread pain impacting on quality life.
Objectives: To assess the relationship between FMS and knee osteoarthritis (KOA) and to evaluate the predictors of this relationship if present.
Patients and Methods: One hundred Iraqi KOA patients and 100 healthy controls were included in this cross-sectional study. Full history was taken and complete clinical examination was done for all patients. Baseline characteristics [age, sex, duration, body mass index (BMI), waist circumference, family history (Hx) of KOA, smoking history, and drug history.] were also documented. Laboratory analysis included complete blood count, erythrocyte

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Publication Date
Wed Dec 30 2020
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Assessment of Quality of Life in a Sample of Iraqi Patients with Psoriasis.
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Psoriasis is a dermatological, chronic, immune-mediated condition. Psoriasis symptoms are not associated with physical burden only, but it may also have psychosocial effects on patients, diminished cognitive control, poor body image and impairments in everyday life. The value of quality of life is important since improving it is the principal goal for non-curative disease. The aim of the current study was to evaluate quality of life in a sample of Iraqi patients with psoriasis. This study is a cross-sectional study that involved 300 already diagnosed psoriasis patients who attended to the center of Dermatology and Venereology, Medical City/Baghdad. The mean age of patients was (35.156 ±10.549 years). The Arabic version of Dermatology Li

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Publication Date
Thu Jan 02 2014
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Experience with treatment of fifty eight Iraqi patients with Acute Myeloid Leukemia
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Background: Adults with Acute Myelogenous Leukemia (AML) have the lowest survival rate of all leukemias. Complete remission (CR) rate after induction therapy is about 55-85%, however 30% of patients fail to achieve remission and they remain alive only for about a year. Consolidation chemotherapy results in 5-year overall survival (OS) of about 30%.

Objectives: To study characteristics of adult patients with AML who attended Baghdad Teaching Hospital, their response to induction therapy and then to consolidation therapy, and their 5-year (OS) and disease free survival (DFS).

Results: Eleven patients who received attenuated induction therapy had a median survival of 6-8 mon

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Publication Date
Tue Mar 30 2021
Journal Name
Iraqi Journal Of Science
Dysregulation of Micro RNA-155 as a Biomarker in Iraqi Patients with Prostate Cancer
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Chronic inflammation can induce proliferative events and posttranslational DNA modifications in prostate tissues through oxidative stress. The miR-155 expression is abnormally increased in tumors. Therefore, this study aims to explore the clinical significance of serum TNF-α and IL-1α as well as miR-155 expression in prostate cancer (PC) patients.

A total of 50 blood samples from patients diagnosed with prostate cancer were collected from the Oncology Department, Baghdad Teaching Hospital, along with samples from 50 healthy volunteers. Serum TNF-α and IL-1α levels in Iraqi males with prostate cancer were estimated by using enzyme-linked immunosorbent

assay (ELISA). The total RNA was extracted from all subjects and con

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Publication Date
Thu Apr 01 2021
Journal Name
Biochemical And Cellular Archives
STUDY OF LYSYL OXIDASE-1 AND KIDNEY FUNCTION IN SERA OF IRAQI PATIENTS WITH DIABETIC NEPHROPATHY
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This study aimed to compare lysyl oxidase-1 level in diabetic patients with and without renal dysfunction, that LOX-1 may be an indicator for the early stage of diabetic nephropathy (DN). In addition to finding it is a relationship with kidney functions in Iraqi diabetic patients with and without renal dysfunction. Blood was obtained from 25 healthy individuals as a control group (G1), 25 diabetic patients with renal dysfunction, and 25 diabetic patients without renal dysfunction. Age range 40-60 years for all subjects. BMI (25-27) Kg/m2 . The serum was used for the analysis of LOX-1, FBG, urea, creatinine and uric acid. Whole blood is used for the determination of HbA1C. Results of FBG and HbA1C revealed a significant increase in G2 and G

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