Objective: The aim of this study is to detect the effect of continuous exposure to Sodium Nitrite on 8-oxoguanine
DNA glycosylase (OGG1) gene which responsible on DNA repairs. DNA repair play a major role in maintaining
genomic stability when DNA exposure to damage. Genomic stability is very important for keeping body cells
healthy and to prevent many types of tumor development. Many genes are responsible for this job; one of them is
OGG1 gene.
Methodology: In current study two groups of mice were chronically exposed to sodium nitrite for six months and
eighteen months while third group was used as a control. Then sizes of OGG1 were estimated.
Results: The results exhibited in the unexposed (control) mice had two different alleles for this gene while the
exposed animals showed more polymorphisms and this finding is independent to the period of exposure.
Conclusion obtained from this study indicated that sodium nitrite has ability to act on this gene that leads to
develop more polymorphisms.
Recommendations: Other research should be done in order to detect how nitrite can act on this gene
Özet
Dünyanın muhtelif yerlerinde yaşayan, farklı din, kültür ve etnik gruba mensup olan insanlar arasında nazar inancının mevcut olduğu bilinmektedir. Nazar inancı İslam dinine inananlar arasında olduğu gibi farklı semavi ve gayri semavi dinlere inanan insanlar arasında da mevcut olduğu çeşitli pratik ve uygulamalardan tespit edilebilir. İnsanlar, nazara gelmemek için çeşitli yollara başvurmaktadırlar. Kötü nazarlı insanlara karşı her zaman bir korku, rahatsızlık ve çekingenliğin var olduğu söylenebilir. Dolayısıyla birçok insan, nazara ve başına kötü bir şeyin gelmemesi için söz konusu nazarı kötü
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