Breast cancer constitutes about one fourth of the registered cancer cases among the Iraqi population (1)
and it is the leading cause of death among Iraqi women (2)
. Each year more women are exposed to the vicious
ramifications of this disease which include death if left unmanaged or the negative sequels that they would
experience, cosmetically and psychologically, after exposure to radical mastectomy.
The World Health Organization (WHO) documented that early detection and screening, when coped
with adequate therapy, could offer a reduction in breast cancer mortality; displaying that the low survival rates
in less developed countries, including Iraq, is mainly attributed to the lack of early detection programs coupled
with inadequate diagnostic and treatment facilities (3)
. Although mammography machines, as main screening
tools for breast cancer, are available in the major hospitals in each province in Iraq, yet those are mainly used
for diagnostic purposes in patients who present with palpable breast lumps. Obviously, due to cost effective
measures, lack of resources and the economical challenges that Iraq is facing, it is not expected that the
authorities could provide mammography devices across every health care centre in the country to be used for
screening of all Iraqi women.
Accordingly, promoting other feasible tools could support in solving that dilemma. Clinical Breast
Examination (CBE) for women, by highly trained health care providers in Primary Health Care Centers, along
with diagnostic mammography in the major hospitals for referred cases, could offer cost effective approaches
for early detection of breast cancer in Iraq. The resources required to provide these services are within the
reach of all countries with limited resources
(4)
.
The issue of raising awareness on breast cancer and its early detection measures needs to be addressed.
Observations reported in Iraqi studies obviously reflect the the limited knowledge of the general population
about the disease, its preventive measures and their ignorance regarding the significance of CBE and early
medical consultation (5, 6)
. Public health awareness campaigns should be endorsed by policy makers to encourage every Iraqi women to look for abnormal signs and symptoms in their breasts and to seek medical
advice promptly.
Introduction: Breast cancer is a significant global health concern, affecting millions of women worldwide. While advancements in diagnosis and treatment have improved survival rates, the impact of this disease extends beyond physical health. It also significantly influences a woman's lifestyle and overall well-being. Objectives: The current study intends to analyze the lifestyle of breast cancer patients who are receiving therapy or are being followed up at the Oncology Teaching Hospital in Medical City, Baghdad, Iraq. Method: The present study uses a descriptive design with an application of an evaluation approach. A convenience sample of 100 women with breast cancer was selected from the Teaching Oncology Hospital at the Medical C
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Background: Breast cancer is a highly heterogeneous disease globally. Trace elements such as copper and zinc have a role in many biochemical reactions as micro source, their metabolism is profoundly altered in neoplastic diseases especially breast cancer which is ranked as the first of female cancers
Objective: The aim of the present study is to study the impact of body mass index and some trace elements in Iraqi women with breast cancer.
Patients and methods: The group of the study consisted of 25 breast cancer patients; their age range was (25–65) years recruited from the Al-Kadhimia Teaching Hospital and 25 apparently healthy women age matched, over a period of 6 months from January 2015 until June 2015. After the diagnosis wa
Background: Breast cancer ranks the first among the Iraqi population since three decades and is currently forming a major public health problem being the second cause of death women. Novel management of breast cancer depends upon precise evaluation of their molecular subtypes; identified by Hormone (Estrogen and Progesterone) receptors and HER2 contents of the primary tumor.
Objective: To assess the rates of the different molecular breast cancer subtypes in the examined tissue specimens belonging to females diagnosed with breast cancer in Iraq; correlating the findings with those reported in the literature at the regional and global levels.
Patients and Methods: This retrospective study documented the findings of tissue biopsy exam
(1)
Background: with the dramatic increase in the use of chest computed tomography (CT) for diagnostic or screening purposes, incidental breast lesions faced more frequently; while most of these incidental breast findings are benign; nevertheless, breast cancer be existing.
Objectives: to determine the imaging characteristic of incidentally detected breast lesions in routine chest computed tomography and to review the outcome of further assessment of these abnormalities.
Patients and methods: a prospective study performed on (33 patients) during the period from October 2014 to November 2015 in AL Shaheed Ghazi Al Hariri hospital, Baghdad teaching hospital, and Radiology Institute at Medical city complex, Baghdad. All patients were fema
Objective:To Evaluate of Estradiol and Prolactin hormones levels for Breast Cancer women in
Baghdad City.
Methodology: The current study was conducted on 60 breast cancer women and 40 apparently
healthy subjects to evaluate the levels of estradiol and prolactin "hormones in the serum" of
({premenopausal & postmenopausal}) breast cancer and healthy controle women. Estradiol and
prolactin hormones estimated for all cases by using the IMMULITE 2000 instrument that performs
chemiluminescent immunoassays results are calculated for each sample.Data were analysed using
SPSS-18.data of two groups was comparison by the student's t-test.
Results: The results showed a non significant""(P>0.05) elevation in the –mean
STAG proteins, which are part of the cohesin complex and encoded by the STAG genes, are known as Irr1/Scc3 in yeast and as SA/STAG/stromalin in mammals. There are more variants as there are alternate splice sites, maybe three open reading frames (ORFs) code for three main proteins, including: SA1 (STAG1), SA2 (STAG2) and SA3 (STAG3). The cohesin protein complex has various essential roles in eukaryotic cell biology. This study compared the expression of the STAG1 gene in four different breast cancer cell lines, including: MCF-7, T-47D, MDA-MB-468, and MDA-MB-231 and normal breast tissue. RNA was extracted from these cell lines and mRNA was converted to cDNA, and then expression of the STAG1 gene was quantified by three sets of specific prim
... Show MoreBackground:Breast abscesses could be successfully treated by percutaneous aspiration of pus and irrigation of the cavity with saline solution.
Objective:To assess the feasibility and effectiveness of percutaneous needle aspiration of breast abscesses under local anesthesia in the outpatient clinic.
Patient and methods:A prospective study of forty three women with breast abscesses attended outpatient clinic at Tikrit teaching hospital and privit clinic for the period from January 2008 to January 2010.All patients had preliminary breast ultrasoundexamination. Percutaneous needle aspiration of pus under local anesthesia was done ,followed by systemic antibiotics. Repeated aspiration was carried out later when deemed necessary and foll
(1)
Background: In breast carcinoma, amplification &/or over-expression of HER-2/neu has been associated with a group of unfavorable prognostic factors. The Food & Drug Administration Agency approved Trastuzumab (Herceptin) for the therapy of metastatic breast cancer but only in patients with amplification &/or over-expression of this gene. Because of these advances, evaluation of HER-2/neu status in breast cancer specimens is of vital importance.
Patients and methods: thirty eight females with breast carcinoma were included in this study. All histologic sections were stained routinely with the hematoxylin and eosin stains and
immunohistochemically for HER2/neu. All cancers were graded and subcatego
Today, the prediction system and survival rate became an important request. A previous paper constructed a scoring system to predict breast cancer mortality at 5 to 10 years by using age, personal history of breast cancer, grade, TNM stage and multicentricity as prognostic factors in Spain population. This paper highlights the improvement of survival prediction by using fuzzy logic, through upgrading the scoring system to make it more accurate and efficient in cases of unknown factors, age groups, and in the way of how to calculate the final score. By using Matlab as a simulator, the result shows a wide variation in the possibility of values for calculating the risk percentage instead of only 16. Additionally, the accuracy will be calculate
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(1)