Objectives: Assessment outcome of DOTS (Directly observed therapy short course) program in Al-Sader City
Sector that was established by the WHO.
Methodology: Three cohorts groups of patients attending Baghdad TB institute and TB center in Al-Sader city
were followed retrospectively. The 1st cohort included (314) patients registered in year (2003), the 2nd cohort
included (327) patients registered in year (2004), the 3rd cohort included (321) patients registered in year
(2005). The collected data were analyzed for case detection, treatment outcomes, retreatment outcomes,
treatment success, and retreatment success in regard to time, age and sex.
Results: The following rates were extracted for the three cohort: Case detection rate within 1st, 2nd, and 3rd
cohort were (73.36%, 64.24%, and 71.49% respectively).Treatment outcomes (cured, completed treatment,
defaulters, treatment failure, died and transfer out) of new smear positive patients within the 1st, 2nd and 3rd
were (71.7%, 12.7%, 10.2%, 3.5%, 1%, 1%), (64.8%, 19.9%, 0.9%, 7%, 0.6%, 6.7%) and (61.4%, 24%, 3.1%, 5.9%,
0.6%, 5% respectively).Retreatment outcomes (cured, completed treatment, defaulters, treatment failure, died
and transfer out) within 1st, 2nd and 3rd cohort were (55.6%, 7.9%, 6.6%, 15.2%, 4%, 10.6%), (44.9%, 7.7%,
2.6%, 21.8%, 4.5%, 18.6%) and (41.8%, 14.6%, 11.4%, 19.6%, 1.9%, 10.8% respectively. Treatment success rate
within the 1st, 2nd and 3rd cohort were (84.39%, 84.7%, and 85.35%) respectively. Retreatment success rate
within the 1st, 2nd and 3rd cohort was (63.57%, 52.56%, and 56.32%) respectively.
Recommendation :Increase case detection rate through increase health awareness to the community about
the mode of transmission and risk of TB disease, Increase the training of health team so that they can follow up
of patients at home, Increase follows up of defaulters to be able to deal with them and a study for relapses
cases is recommended
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Epigenome-wide analysis of DNA methylation was performed for 20 patients at two timepoints during treatment. The prognostic significance of differentially methylated regions (DMRs) was assessed in independent cohorts of 139 and 1
Background: Ankylosing spondylitis (AS) is inflammation of the sacroiliac joints and spine, associated with clinical symptoms such as pain and stiffness in the vertebral column, after which, in a considerable number of individuals, new bone growth occurs. Objective: The current research study attempted to find out whether the presence of SNPs in TNF receptor [TNFRSF1A (rs767455), TNFRSF1B (rs1061622)] encoding genes could influence patients' outcomes to etanercept in a specimen of Iraqi AS patients. Patients and methods: Sixty patients with established AS receiving only etanercept were selected to be enrolled in this research with a mean age of 40.75 ± 8.67 years, 51 patients of them were males and only 9 patients were females. Patients we
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