Objective: To determine the effectiveness of hypothermia on renal functions for patients undergoing
coronary artery bypass graft CABG surgery.
Methodology: A purposive (non-probability) sample of (50) patients undergoing Isolated coronary artery
bypass graft surgery consecutively admitted to the surgical ward, and they were followed up in the
intraoperative, Intensive Care Unit (ICU) and in the postoperative (surgical ward). Post-operative renal function
test (glumeruler filteration rate (GFR) by using the Crockroft-Gault formula and serum creatinine level) was
determined first week post operative and post operative renal function was classified on the base of peak of
the serum creatinine level and decline of glomeruler filteration rate(GFR) as following : normal renal function
serum creatinine concentration and decline in(GFR) less than 25% from preoperative, moderate renal
dysfunction increase serum creatinine concentration and decline in(GFR) 25%-50% from preoperative, sever
renal dysfunction increase serum creatinine concentration and decline in(GFR) more than 50% from
preoperative test.
Results: results of this study show that (78%) from the sample develop post operative renal dysfunction and
the highly percentage of them are male (50%), advance age 60-70 (60%), smoking (47.0%), diabetes mellitus
DM (68%), cardiopulmonary bypass 180 and more (57.20%), New York Heart Association calcification NYHA
class III(47.5%) and patient without Intra Aortic Balloon Pump IABP(50,0%) . We conclude from the study that
highly percentage of patient undergoing isolated CABG may develop postoperative renal dysfunction even
when using hypothermic strategy as a protective measure and the patients with DM, male, advance age,
smoker, prolong time of CPB (more than 180 minutes), NYHA class III and patient without IABP are considered
as patient at high risk to develop postoperative renal dysfunction.
Recommendations: The researcher recommended that to find addition strategy rather than hypothermia
to protect renal function especially with the high risk patients during isolated CABG surgery.
(27)
(21)
(7)
(7)
(1)
Abstract: E2F6 is a member of the E2F family of transcription factors involved in regulation of a wide variety of genes through both activation and repression. E2F6 has been reported as overexpressed in breast cancers but whether or not this is important for tumor development is unclear. We first checked E2F6 expression in tumor cDNAs and the protein level in a range of breast cancer cell lines. RNA interference-mediated depletion was then used to assess the importance of E2F6 expression in cell lines with regard to cell cycle profile using fluorescence-activated cell sorting and a cell survival assay using (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT). The overexpression of E2F6 was confirmed in breast tumor cDNA samp
... Show More
(8)
(6)
(4)
(3)
(23)
(22)
Derivatives of Schiff-bases possess a great importance in pharmaceutical chemistry. They can be used for synthesizing different types of bioactive compounds. In this paper, derivatives of new Schiff bases have been synthesized from several serial steps. The acid (I) was synthesized from the reaction of dichloroethanoic acid with 2 moles of p-aminoacetanilide. New acid (I) converted to its ester (II) via the reaction of (I) with dimethyl sulphate in the present of anhydrous of sodium carbonate and dry acetone. Acid hydrazide (III) has been synthesized by adding 80% of hydrazine hydrate to the new ester using ethanol as a solvent. The last step included the preparation of new Schiff-bases (IV-VIII) by the reaction of acid hydrazide with
... Show More
(3)
(1)
The zeolite's textural properties have a significant effect on zeolite's effectiveness in the different industrial processes. This research aimed to study the textual properties of the NaX and FeX zeolites using the nitrogen adsorption-desorption technique at a constant low temperature. According to the International Union of Pure and Applied Chemistry, the adsorption-desorption isotherm showed that the studied materials were mixed kinds I/II isotherms and H3 type hysteresis. The Brunauer-Emmett-Teller isotherm was the best model to describe the nitrogen adsorption-desorption better than the Langmuir and Freundlich isotherms. The obtained adsorption capacity and Brunauer-Emmett-Teller surface area values for NaX were greater than FeX. Ac
... Show More
(3)
This research considers the preservation of environment through recycling old toys. This is achieved by transforming the old toys into educational clothing accessories for kindergarten stages. The research methodology adapts both descriptive and applied approaches. The research questionnaire targeted a sample of 35 teachers to collect information about the waste toys in kindergarten. Also, another sample of 30 teachers and mothers were targeted to measure the suitability of the clothing designs for the early childhood stages. The results shows that both teachers and mothers were well satisfied with clothing accessories designed with the toys waste. This concept contributes to limiting the pollution caused by toys and could save time, eff
... Show More