Objective: To determine the effectiveness of hypothermia on renal functions for patients undergoing
coronary artery bypass graft CABG surgery.
Methodology: A purposive (non-probability) sample of (50) patients undergoing Isolated coronary artery
bypass graft surgery consecutively admitted to the surgical ward, and they were followed up in the
intraoperative, Intensive Care Unit (ICU) and in the postoperative (surgical ward). Post-operative renal function
test (glumeruler filteration rate (GFR) by using the Crockroft-Gault formula and serum creatinine level) was
determined first week post operative and post operative renal function was classified on the base of peak of
the serum creatinine level and decline of glomeruler filteration rate(GFR) as following : normal renal function
serum creatinine concentration and decline in(GFR) less than 25% from preoperative, moderate renal
dysfunction increase serum creatinine concentration and decline in(GFR) 25%-50% from preoperative, sever
renal dysfunction increase serum creatinine concentration and decline in(GFR) more than 50% from
preoperative test.
Results: results of this study show that (78%) from the sample develop post operative renal dysfunction and
the highly percentage of them are male (50%), advance age 60-70 (60%), smoking (47.0%), diabetes mellitus
DM (68%), cardiopulmonary bypass 180 and more (57.20%), New York Heart Association calcification NYHA
class III(47.5%) and patient without Intra Aortic Balloon Pump IABP(50,0%) . We conclude from the study that
highly percentage of patient undergoing isolated CABG may develop postoperative renal dysfunction even
when using hypothermic strategy as a protective measure and the patients with DM, male, advance age,
smoker, prolong time of CPB (more than 180 minutes), NYHA class III and patient without IABP are considered
as patient at high risk to develop postoperative renal dysfunction.
Recommendations: The researcher recommended that to find addition strategy rather than hypothermia
to protect renal function especially with the high risk patients during isolated CABG surgery.
The Light and the Dark is the fourth novel in a series written by Charles Percy Snow where it tackles a phase of gifted scholar and remarkable individual Roy Calvert as he search for a source of power and meaning in life to relieve his inner turmoil. The character Roy Calvert is based on Snow's friend, Charles Allbery who exposes the message the character of Roy intends to convey in a certain phase of his life and the prophecy the novel carries amid catastrophe so widespread in the thirties of the twentieth century
This paper focuses on developing a self-starting numerical approach that can be used for direct integration of higher-order initial value problems of Ordinary Differential Equations. The method is derived from power series approximation with the resulting equations discretized at the selected grid and off-grid points. The method is applied in a block-by-block approach as a numerical integrator of higher-order initial value problems. The basic properties of the block method are investigated to authenticate its performance and then implemented with some tested experiments to validate the accuracy and convergence of the method.
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Abstract: E2F6 is a member of the E2F family of transcription factors involved in regulation of a wide variety of genes through both activation and repression. E2F6 has been reported as overexpressed in breast cancers but whether or not this is important for tumor development is unclear. We first checked E2F6 expression in tumor cDNAs and the protein level in a range of breast cancer cell lines. RNA interference-mediated depletion was then used to assess the importance of E2F6 expression in cell lines with regard to cell cycle profile using fluorescence-activated cell sorting and a cell survival assay using (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT). The overexpression of E2F6 was confirmed in breast tumor cDNA samp
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Derivatives of Schiff-bases possess a great importance in pharmaceutical chemistry. They can be used for synthesizing different types of bioactive compounds. In this paper, derivatives of new Schiff bases have been synthesized from several serial steps. The acid (I) was synthesized from the reaction of dichloroethanoic acid with 2 moles of p-aminoacetanilide. New acid (I) converted to its ester (II) via the reaction of (I) with dimethyl sulphate in the present of anhydrous of sodium carbonate and dry acetone. Acid hydrazide (III) has been synthesized by adding 80% of hydrazine hydrate to the new ester using ethanol as a solvent. The last step included the preparation of new Schiff-bases (IV-VIII) by the reaction of acid hydrazide with
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