Objectives: Determine the age and gender distribution of children who experience diabetes mellitus (DM) under
the age of 15 years and the presence of some associated factors that might be a predisposing factor for the
disease including obesity.
Methodology: A cross-sectional study was conducted at diabetic clinic in Children Welfare Teaching Hospital
in Baghdad City during 2006. The study sample included diabetic children less than 15 years of age. Data were
taken from the patients' record and by direct interview with the patients' parents. Information included
demographic data, as well as past history of the patient and his/her family relative to diabetes and other immune
diseases.
Results: Data analysis showed that there was an equal distribution of patients among the three age groups (I-5,
6-10-, and 11-15 years) in a rate of 33% for each. Females had higher incidence rate (660/o) than males. Onset of
the disease was mostly at age group I-3 years (32%) followed by age group 4-6 years (30%). IIistory of viral
illness was present in 24% of patients and a positive family history of DM was found in 23% of them, and a
family history of autoimmune disease was positive in 13% of cases. Body weight at the first visit to the clinic
was mainly below the 50th percentile (42% within the 25th percentile) and only 4% of patients had a body
weight within the 75th percentile.
Recommendations: Health education about the disease and provision of health centers those are easily
accessible for early diagnosis and treatment and uninerrupted insulin supply.
miRNAs regulate protein abundance and control diverse aspects of cellular processes and biological functions in metabolic diseases, such as obesity and diabetes. Lethal-7(Let-7) miRNAs specifically target genes associated with diabetes and have a role in the regulation of peripheral glucose metabolism. The present study aimed to describe the gene expressions of the let-7a gene with the development of diabetes in Iraq and the difference in the expression of this gene in patients with diabetes and healthy individuals. The association between age and gender with the development of diabetes was studied in this study and the results were compared with those of healthy individuals in the group of control. Based on the obtained results, there was
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