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Evaluation of Antioxidant Activity of Acoholic Extracts from Pleurotus ostreatus (P2) In Vivo

In this study found treatment mice exposed to CCl4 with the alcoholic extract of Pleurotus ostreatus (P2) at (25) mg/ml appeared to exert a beneficial effect since the activities of catalase, was significantly (p<0.05) higher in liver treatment with alcoholic extract of P. ostreatus (P2) (37.290+2.638) μmol/mg than in aqueous extract for the same fungus (36.557+2.231) μmol/mg. Super oxide dismutase (SOD) was significantly (p<0.05) higher in liver treatment with alcoholic extract of P. ostreatus (P2) at (25) mg/ml (17.863+0.454)U/mg than in aqueous extract (17.863+0.454) U/mg for the same fungus and same concentration. Glutathione peroxidase (Gpx) was significantly (p<0.05) higher in liver treatment with alcoholic extract of P. ostreatus(P2) at (25) mg/ml (29.260+1.666)μmol/mg than in aqueous extract (24.660+1.130)μmol/mg for the same fungus and same concentration. Alcoholic extract of P .ostreatus (P2) at (25) mg/ml induce a non-apoptotic, apoptosis was (0.0657+0.0047%) ,in aqueous extract was (0.0770+0.0060%). Histopathological study appeared liver cells exposed to CCl4, CCl4 made severe degeneration and necrotic change in liver parenchyma by evidence of apoptosis in some hepatocytes , in sinusoids showed slight congestion with blood vessel and thrombus formation. Liver cells of mouse exposed to CCl4 and treated with alcoholic mushroom extract and appeared the liver cells returned like control. the tissue treatment by aqueous extract of P.ostreatus (P2) at (25) mg/ml appeared mononuclear cells aggregation.

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Publication Date
Fri Oct 01 2021
Journal Name
International Journal Of Drug Delivery Technology
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Publication Date
Sun Apr 30 2023
Journal Name
Al-kindy College Medical Journal
In Vitro Antimicrobial Activity of Essential Oil Derived from Callistemon viminalis Aerial Part

Background: Essential oils extracted from plants have been widely used in antimicrobial activity, particularly the Callistemon viminalis, with a high number of essential oils extracted.

Objectives: To identify the chemical composition of essential oil derived from Callistemon viminalis and evaluates its antimicrobial activity against selected bacterial and fungal strains.

Subjects and methods: During the study, the antimicrobial activity of different selected essential oils on some bacteria (Escherichia coli, Pseudomonas aeruginosa, Salmonella enteritidis, Staphylococcus aureus, and Streptococcus pneumonia) and fungus (Candida albicans) was evalua

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Publication Date
Tue Aug 31 2021
Journal Name
Iraqi Journal Of Science
Synthesis of Silver Nanoparticles Using L.Rosa Flowers Extracts: Thermodynamic and Kinetic Studies on the Inhibitoty Effects of Nanoparticles on Creatine Kinase Activity

      The present work investigates the synthesis of silver nanoparticles (AgNPs) by a biological method using L.Rosa flower extract and silver nitrate as precursors. Optimum conditions of synthesis were studies, such as pH, temperature, concentration of extract, concentration of silver nitrate, and stability with time. Characterization of AgNPs was carried out using UV-visible Spectroscopy, Scanning Electron Microscopy, X-Ray Diffraction, Fourier Transform Infrared and Transmission Electron Microscopy. The biosynthesized AgNPs exhibited inhibitory effects on creatine kinase activity in the sera of patients with myocardial infarction, compared with control subjects. Thermodynamic and kinetic studies of c

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Publication Date
Mon Jun 29 2015
Journal Name
Iraqi Journal Of Market Research And Consumer Protection
Study of Antioxidation Activity of Sulfated Polysaccharide Extracted From Green Algae Enteromorpha sp.: Study of Antioxidation Activity of Sulfated Polysaccharide Extracted From Green Algae Enteromorpha sp.

Samples of the green algae were collected from water of Shatt al-Arab in Garmat Ali in Basra. After purification, the green algae identified on Enteromorpha sp. The samples were dried and milled, then sulfated polysaccharides were extracted with hot water at 90°C precipitated with absolute ethanol, dialysed and lyophilized. The chemical composition was total sugars 56.4%, protein 1.3% and sulfur 19.7%. Antioxidation activity of sulfated polysaccharides was studied by four method and included estimation of ability of scavenging hydroxylated radicals, the results showed an increased in ability with increasing concentrations. Ability of scavenging and was 59.86% at the concentration of 2.5 mg/ ml, but BHT was 81.36%. Ability of scavenging

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Publication Date
Wed Dec 01 2021
Journal Name
Iraqi Journal Of Science
Evaluation of the antibacterial effects of Eucalyptus camaldulensis L., Glycyrrhiza glabra L. and Morus nigra L. extracts against some pathogenic bacteria in vitro

This study aimed to test the effect of using different concentrations of three different plants extracts to inhibit the growth of gram negative and gram positive bacteria by two technics. Eucalyptus camaldulensis bark, Glycyrrhiza glabra rhizomes and Morus nigra leaves ethanolic extract at (0,20,30,40 and 50 mg/ml) were used. The antimicrobial activity and the biofilm inhibition assay used with these extracts showed positive effect in inhibiting the growth of bacteria. E.amaldulensis extract showed the higher effect than G. glabra and M.nigra extracts in antimicrobial activity assay, while the effect of E. camaldulensis extract in biofilm inhibition assay was higher than G. glabra that was higher than M. nigra extracts for both gram nega

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Publication Date
Thu May 25 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Purification, Characterization and Antifungal Activity of Chitinase from Serratia marcescens Isolated from Fresh Vegetables

  Seven [35%] and five [25%] Serratia marcescens  isolates were obtained out of 20 samples of lettuce and 20 samples of spinach, respectively, taken from different locations in a farm in Baghdad city. The isolate that produced chitinase in higher level was chosen to purify chitinase through several stages of purification including: ammonium sulfate precipitation, DEAE- sephadex ion exchange chromatograpgy and sephadex G-200 gel filtration with 89.5- fold purification and 30% recovery.       The purified chitinase was characterized and the molecular weight of enzyme was 59000 daltons by using gel filtration chromatography. The optimum pH and temperature of the purified chitinase were 6.0 and 50°

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Publication Date
Wed Jun 10 2015
Journal Name
Ibn Al-haitham Journal For Pure And Applied Science
New Schiff Base Derived From Folic Acid and 3- Aminoacetophenone and its Metal Complexes with Some Transition Metals and Evaluation of Their Biological Activity

The ligand [Potassium (E)-(4-(((2-((1-(3-aminophenyl) ethylidene) amino)-4-oxo-1,4- dihydropteridin-6-yl) methyl) amino)benzoyl)-L-glutamate] was prepared from the condensation reaction of folic acid with (3-aminoacetophenone) through Schiff reaction to give a new Schiff base ligand [H2L]. The ligand [H2L] was characterized by elemental analysis CHN, atomic absorption (A.A), (FT-I.R.), (U.V.-Vis), TLC, E.S. mass (for spectroscopes), molar conductance, and melting point. The new Schiff base ligand [H2L], reacts with Mn(II), Co(II), Ni(II), Cu(II), Cr(III) and Cd(II) metal ions and (2-aminophenol), (metal : derivative ligand : 2-aminophenol) to give a series of new mixed complexes in the general formula:- K3[M2(HL)(HA)2], (where M=Mn(II) and

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Publication Date
Wed Jun 30 2010
Journal Name
Iraqi Journal Of Chemical And Petroleum Engineering
Characterization and Cracking Activity of Zeolite Prepared from Local Kaolin

The synthesis of zeolite NaX from locally available kaolin has been studied. The operating conditions for zeolite NaX production from kaolin with good crystallinity were as follows; a gel formation step of metakaolin in alkaline medium in presence of additional silica to crystallize the zeolite was achieved at 60 oC for 1 hr,and with stirring. In ageing step of the reactants at room temperature for 5 days and crystallization step at 87±2 oC for 24 hr. The catalytic activity of catalyst prepared from local kaolin was studied by using cumene cracking as a model for catalytic cracking and compared with standard HY zeolite and HX zeolite catalysts. The activity test was carried out in a laboratory continuous flow unit with fixed bed reactor

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Publication Date
Sun Dec 01 2019
Journal Name
Journal Of Medicinal And Chemical Sciences
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Publication Date
Fri Dec 01 2023
Journal Name
Baghdad Science Journal
Ni2+, Pt4+, Pd2+, and Mn2+ Metal ions Complexes with Azo Derived from Quinolin-2-ol and 3-amino-N-(5-methylisoxazol-3-yl) Benzenesulfonamide: Synthesis, Characterization, Thermal Study ,and Antioxidant Activity

 

Diazotization reaction between quinolin-2-ol and (2-chloro-1-(4-(N-(5-methylisoxazol-3-yl)sulfamoyl)phenyl)-2l4-diazyn-1-ium was carried out resulting in ligand-HL, this in turn reacted with the next metal ions (Ni2+, Pt4+, Pd2+, and Mn2+)  forming stable complexes with unique geometries such as (tetrahedral for both Ni2+ and Mn2+, octahedral for Pt4+ and square planer for Pd2+ ). The creation of such complexes was detected by employing spectroscopic means involving ultraviolet-visible which proved the obtained geometries, fourier transfer proved the formation of azo group and the coordination with metal ion through it. Pyrolysis (TGA &

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