A series of experiments were conducted to evaluate the antibacterial effect of Cinnamomum zealynicum bark aqueous , methanol, and chloroform extracts against some gram positive and gram negative pathogenic bacteria which isolated from wound, throat infection, urine and stool during the period from December /2013 to February /2014 from Alkarama hospital in Wasit. All these isolates were identified by using VITEK2 compact system. Antibiotic sensitivity test of the bacterial isolates was determined for ten antibiotics. Chemical analysis showed that Cinnamomum zeylanicum bark extracts contained different active compounds (phenoles, alkaloids, tannins, glycosides, coumarins, saponins, resins flavones and essential oil). The laboratory tests of antibacterial activity , showed that Staphylococcus aureus was the most affected by the extracts under study then followed with Enterococcus faecalis, Streptococcus pneumoniae, Escherichia coli and Klebsiella pneumoniae respectively. Aqueous extract showed highest values in MIC (400 μg/ml) and MBC (450 μg/ml) for S aureus, followed by chloroform (350 μg/ml, MIC and 400 μg/ml, MBC), then methanol (335 μg/ml, MIC and 375 μg/ml MBC) while the lowest values were recorded for K. pneumonia (MIC 175, 200 and 250 μg/ml, and MBC 200, 250 and 300 μg/ml respectively). In other hand inhibition zones appeared at 200 μg/ml for S. aureus and E. faecalis, and at 300 μg/ml for E. coli and S. pneumonia, and at 400 μg/ml for K. pneumoniae for aqueous extract, while methanol extract inhibition zones started from 100 μg/ml for S. aureus, and at 200 μg/ml for S. pneumonia and E. faecalis, and at 300 μg/ml for K. pneumonia and E. coli. Chloroform extract showed inhibition zones for S. pneumonia, E. faecalis and S. aureus at 200 μg/ml and for E coli and K. pneumoniae at 300 μg/ml.
There is a continuous and massive need for newer cephalosporins that should have resistance against β-lactamases and can be used orally. An approach of using cephalexin, as a well-studied and potent antibacterial compound is considered to prepare new designed derivatives. These derivatives include the incorporation of amino acid moiety linked through an amide bond with the α-amino group of cephalexin. Certain aliphatic amino acids were used, such as glycine, alanine, valine and proline. The chemical structures of these derivatives were confirmed by IR spectroscopy and elemental analyses. All the synthesized compounds were subjected for preliminary evaluation of antimicrobial activity using well diffusion method, against certa
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Background: Ulcerative colitis is a chronic inflammatory condition characterized by relapsing and remitting episodes of inflammation limited to the mucosal layer of the colon.Loop ileostomy might be helpful in the management of the disease.
Objective: To evaluate the role of loop ileostomy in the management of ulcerative colitis.
Methods: Between Januarys 2008 and January 2018, patients with fulminant ulcerative colitis resistant to medical therapy had been referred to our surgical unit and were included in our study. Assessment of the patients’ medical status (serum electrolytes, total serum protein, complete blood count, erythrocyte sedimentation rate, general stool exam,and abdominal ultrasound
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Celiac disease (CD) is an autoimmune disorder characterized by chronic inflammation that essentially affects the small intestine and is caused by eating gluten-containing foods. This study sought to determine gene expression of NLRP3 Inflammasome in peripheral blood of Iraqi CD children using quantitative real-time PCR (qRT-PCR) assay. Thirty children with CD (12 males and 18 females) were enrolled in the study and their age range was 3-15 years. The diagnosis of the disease was confirmed by serological examinations and intestinal endoscopy. A control sample of 20 age-matched healthy children was also included. The children were stratified for age, gender, body max index (BMI), histological findings, and marsh classification. Furthe
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Amebiasis, related to the pathogenic parasite Entamoeba histolytica, is a prominent cause of diarrhea globally. Amebiasis is primarily a disease of impoverished communities in developing nations, although it has recently arisen as a significant infection among returning tourists and immigrants. Severe cases are linked to a high case fatality rate. Although polymerase chain reaction (PCR)-based diagnosis is becoming more widely available, it is still underutilized. Treatment with nitroimidazoles is now suggested, however novel parasite medication research is a top priority. To avoid problems, amebiasis should be considered before corticosteroid therapy. Because there is no effective vaccination, sanitation and availability to clean w
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The aim of this paper is to present method for solving ordinary differential equations of eighth order with two point boundary conditions. We propose two-point osculatory interpolation to construct polynomial solution.
The research attempts to identify the pattern of punctuation in contemporary Iraqi poetry through delving into the poetry of an Iraqi poet belonging to the seventieth generation, Namik Abdul Deeb, who belongs to the poets of Arab modernity in general, the research has reached many results, including that the signs of deletion were vocabulary marks any They are located in the center of the poetic singular, or inline markers, which are those that fall within the poetic line of the prose poem separating its vocabulary, or cross-sectional marks located within the poetic passages that are part of the poetic text, and finally text marks which are located within the poetic text and fragmented into Parts. The research also found that the work of
... Show MoreGranular carbon can be used after conventional filtration of suspended matter or, as a combination of filtration - adsorption medium. The choice of equipment depends on the severity of the organic removal problem, the availability of existing equipment, and the desired improvement of adsorption condition.
Design calculations on dechlorination by granular - carbon filters considering the effects of flow rate, pH , contact time, head loss and bed expansion in backwashing , particle size, and physical characteristics were considered assuming the absence of bacteria or any organic interface .
Iodine-131 has become an essential radionuclide used in nuclear medicine for clinical and research purposes. The increase use of this radionuclide in medicine for diagnostic and treatment of thyroid diseases creates a demand to obtain a feasible methodology for occupational or accidental monitoring of internal contamination. In this study, two techniques were employed to find an appropriate one of in vivo bioassay for evaluating Iodine-131 body content. A scanning Whole Body Counter (WBC) equipped with 6NaI (Tl) scintillation detector, an anthropomorphic phantom and point source were used. The results showed that the counter sensitivity, as a first approach (conventional method), had a logarithmic and significant correlation w
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