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Potentials of Iron Oxide Nanoparticles (Fe3O4): As Antioxidant and Alternative Therapeutic Agent Against Common Multidrug-Resistant Microbial Species

     For the treatment of pathogenic bacterial infections, multidrug resistance (MDR) has become a major issue. The use of nanoparticles is a promising strategy for combating medication resistance in a variety of pathogens that cause deadly diseases. The goal of our research was to extract multidrug-resistant bacteria from wound infections and then use iron oxide nanoparticles (Fe3O4) as alternative therapeutic agents in vitro. Gram staining, morphological attributes evaluation, and biochemical testing were used to assess the microbes. The Kirby-Bauer disk diffusion method was used to test MDR-bacterial strains against several antibiotics; the majority of these isolates were resistant to ceftazidime, amoxicillin, Gentamicin, and tetracycline. the iron oxide nanoparticles were produced by the co-precipitation method and were confirmed by changing the color to dark black as well as the Scanning Electron Microscope (SEM) and Transmission Electron Microscope (TEM) analysis that shows the shape and average size between (29.03-56.54) nm. The highest effect of iron oxide nanoparticles (Fe3O4) on the growth of Proteus.mirabilis (P.mirabilis) was as it was found that the average diameter of the inhibition zone was 22.66±1.15 mm, followed by Staphylococcus.epidermidis (S.epidermidis), Acinetobacter.baumannii (A.baumannii) with the average diameter of the inhibitory zone it was 21.66±1.52 mm, 20.33±1.53 mm respectively, and Candida.albicans (C.albicans) was 18.33±1.15 mm at 100 µgmL-1 (stock). The synthesized iron oxide nanoparticles (Fe3O4) are used to capture rapidly microbes under the magnetic field effect. The antioxidant activity DPPH of the iron oxide nanoparticles (Fe3O4) showed 29.3%, 42.2%, 58.6%, 67.4%, and 74 % at a concentration (6.25, 12.5, 25, 50, 100) µgmL-1 respectively, it demonstrated that the scavenging percentage increase with increasing the iron oxide nanoparticles (Fe3O4) concentrations.

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Publication Date
Sat Aug 31 2019
Journal Name
Iraqi Journal Of Physics
Investigation the effect of post deposition thermal treatment on properties P3HT and P3HT:PCBM blend.

  This work reports the study of heat treatment effect on the structural, morphological, optical and electrical properties of poly [3-hexylthiophene] and its blend with [6,6]-phenyl C61 butyric acid methyl ester ( P3HT:PC61BM). X-ray diffraction (XRD) measurements show that the crystallinity of the films increased with annealing. The evaluation of surface roughness and morphology was investigated using atomic force microscope (AFM), and field emission scanning microscope(FESEM). The optical properties were emphasized a strong optical absorption of P3HT compared with the blend. Hall effect measurement was used to study the electrical properties which revealed there is an increase in the electrical conductivity and Hall mobility of th

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Publication Date
Sun Mar 20 2016
Journal Name
Al-academy
Design trends of the counterfeit product and the original competition: عبد الخالق سمين فتاح

The problem of the research represented by knowing the approaches which presented by knowing the design guides and the design styles which the imitation products enter upon it to be able to competitor the other original products .The research aim was to comparison the design approaches of the functional performance and the utilizations for the imitation and the original products , however the research limits contained study products samples of the kitchen electric equipments which available in local markets of Baghdad city for the period (2000 – 2013) .After the view of research back for the subject fundamental basics and investigating research sample to be complete to a group of results and conclusions and the most marked of her were

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Publication Date
Sun Apr 09 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Morphological and Histological Study of the Pancreas Gland in the Local Bat ( Pipisterllus kuhlii)

The present study aimed to investigate the morphological and histological structure of pancreas in the bat,(Pipistrellus kuhlii). Pancreas was represented by compact pancreatic tissue which is divided into three parts : head , body and tail, its color is whit to yellow. The pancreatic tissue is located in the abdominal cavity near to the mass of intestine in the mesenteric network , which is connected with the coiled region of the duodenum in one side and with the extended mesenteries between the dorsal part of stomach and the abdominal part of spleen from the other side. The pancreas gland is surrounded by a loose connective tissue, the trabeculae are extended from it and divided the gland into many lobules which are different in shape

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Publication Date
Wed Mar 29 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
A Comparative Biochemical Study of Proteins Profile in Iraqi Children and Adolescent with ?-Thalassemia

The aim of the present research is to study different protein fractions in sera of children and adolescent with  β –thalassemia major and minor and to compare the results with that of healthy control.One hundred fifty children and adolescents were enrolled in this study,including 50 patients with β- thalassemia major , 50 patients with  β- thalassemia minor as pathological control group and another apparently 50 healthy individuals as a control group. The age of all studied  groups ranged from (4-18)years.Total protein, albumin and immunoglobulins were estimated in sera of all subjects.  A Significant  decrease  was  found  in  the  total  protein and  albumin&nb

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Publication Date
Wed Mar 16 2016
Journal Name
The Iraqi Journal Of Agricultural Sciences
PERFORMANCE EVALUATION OF FIELD AND GENETIC FOR SOME SIXTH RADIO GENERATION MUTANTS IN TOMATO

The study was conducted at the fields of the Department of Horticulture and Landscape Gardening, College of Agriculture, University of Baghdad " Abu Ghraib" during the growing seasons 2013-2014 to Evaluate the Vegetative growth , yield traits and genetic parameter of some tomato mutants. Results showed significantly increased of plant height in M6-2 mutant 245cm in Comparison with M6- 3 130 cm . M6-4 mutant significantly increasing of floral clusters 13 . Mutant M6-3 showed significantly increasing the average of, fruit weight 125.9g and plant yield 7.17 kg.plant-1 as comparison with M6-2 which showed decreasing of average of fruit weight and plant yield 79.40g and 4.38 kg.plant-1 respectively. Also results showed the highest Genetic variat

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Publication Date
Fri Sep 15 2023
Journal Name
Journal Of Baghdad College Of Dentistry
Osseointegration effects of whey protein (histological and histomorphological observations): An experimental study on rabbits

Background: Whey protein is the green-yellow colored, liquid portion of the milk, and it is also called the cheese serum, it is obtained after the separation of curd, during the coagulation of the milk. It contains a considerable amount of α-helix pattern with an evenly distributed hydrophobic and hydrophilic as well as basic and acidic amino acids along with their polypeptide chain. The major whey protein constituents include β-lactoglobulin (β-LG),α-lactalbumin (α-LA), immunoglobulins (IG), bovine serum albumin (BSA), bovine lactoperoxidase (LP), bovine lactoferrin (BLF) and minor amounts of a glycol macro peptide (GMP). Osseointegration can be defined as a process that is immune driven which leads to the formatio

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Publication Date
Thu Mar 30 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
The In Situ Expression of IL-6 and IL-1? in breast cancer patients

Breast cancer is the second most common cancer in women world. Multiple Cytokines appear to have a dominant role in human breast cancer formation. Estimation of the in situ expression of  IL-6 and IL-1β in breast cancer patients. A sixty patients with breast cancer BC were divided into two clinical subgroups, (30) with malignant breast cancer MBC and (30) with benign breast tumor as a control group according to histological examination. In situ hybridization technique used for detection of IL-6 and IL-1β mRNA sequence in two groups.  The results showed that percentages of mRNA expression of IL-6 and IL-1β were in (≥ 11-50%) for malignant breast cancer. This research also investigated that (73.3%) of beni

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Publication Date
Tue Jan 11 2022
Journal Name
Iraqi Journal Of Science
Evaluation of some Biochemical and Endocrine Profiles in transfusiondependent Iraqi major β - thalassemia patients

Endocrine Abnormalities in β-thalassemia major are common disturbing
complications, that need prompt management. Importance of this work was to
evaluate the some biochemical parameters and endocrine hormones related to
the pubertal maturity and fertility status in cases with thalassemia. A sixty patients
[38 males and 22 females] with β - thalassemia major against 30 healthy subjects
[17 males and 13 females] were enrolle . The Blood levels of, Leptin, Vitamin D,
thyroid function test, parathyroid hormone, ghrelin, and sex hormones were
determined in the blood. Body Mass Index (BMI) was also evaluate. Results
showed that besides lower BMI, all hormones assessed were significantly lower in
thalassemia β-major

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Publication Date
Sat Dec 31 2022
Journal Name
Mathematical Modelling Of Engineering Problems
Experimental and Numerical Study of Open Channel Flow with T-Section Artificial Bed Roughness

Experimental and numerical studies have been conducted on the effects of bed roughness elements such as cubic and T-section elements that are regularly half-channel arrayed on one side of the river on turbulent flow characteristics and bed erosion downstream of the roughness elements. The experimental study has been done for two types of bed roughness elements (cubic and T-section shape) to study the effect of these elements on the velocity profile downstream the elements with respect to different water flow discharges and water depths. A comparison between the cubic and T-section artificial bed roughness showed that the velocity profile downstream the T-section increased in smooth side from the river and decrease in the rough side

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Publication Date
Sun Mar 07 2010
Journal Name
Baghdad Science Journal
Structural and Optical Properties of SnS2:Cu Thin films prepared by chemical Spbay Pyrolysis

Thin filis have been prepared from the tin disulphide (SnS2 ), the pure and the doped with copper (SnS2:Cu) with a percentages (1,2,3,4)% by using ahemical spray pyrolysis techniqee on substrate of glass heated up to(603K)and sith thicknesses (0.7±0.02)?m ,after that the films were treated thermally with a low pressure (10-3mb) and at a temperature of (473K) for one hour. The influence of both doping with copper and the thermal treatment on some of the physical characteristics of the prepared films(structural and optical) was studied. The X-ray analysis showed that the prepared films were polycrystalline Hexagonal type. The optical study that included the absorptance and transmitance spectra in the weavelength range (300-900)nm

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